Thymoquinone suppression of the human hepatocellular carcinoma cell growth involves inhibition of IL-8 expression, elevated levels of TRAIL receptors, oxidative stress and apoptosis

Thymoquinone suppression of the human hepatocellular carcinoma cell growth involves inhibition of IL-8 expression, elevated levels of TRAIL receptors, oxidative stress and apoptosis

Hepatocellular carcinoma (HCC) is the fourth most common solid tumor worldwide. The chemokine interleukin-8 (IL-8) is overexpressed in HCC and is a potential target for therapy. Although the transcription factor NF-κB regulates IL-8 expression, and while thymoquinone (TQ; the most bioactive constitu...

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Bibliographic Details
Main Authors: Ashour, Abdelkader Elbadawy Abbas, Abd-Allah, Adel R. A., Korashy, Hesham M., Attia, Sabry M., Alzahrani, Abderlrahman Z., Saquib, Quaiser, Bakheet, Saleh A., Abdel-Hamied, Hala E.
Format: Article
Language:English
English
Published: Springer US 2014
Subjects:
RM Therapeutics. Pharmacology
Online Access:http://irep.iium.edu.my/63263/
http://irep.iium.edu.my/63263/1/8129_Thymoquinone%20suppression%20of%20the%20human.pdf
http://irep.iium.edu.my/63263/2/8129_Thymoquinone%20suppression%20of%20the%20human_SCOPUS.pdf

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