Methicillin-resistant staphylococcus aureus (MRSA): epidemiology and SCCmec typing

Staphylococcus aureus is a major human pathogen. It causes a wide range of infections in the hospital setting as well as in the community environment. A broad variety of infections, ranging from minor pyodermas to life-threatening infections can be caused by S. aureus. The adaptive power of S. aureu...

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Main Authors: Mohamamd Alarosi, Nasreen, Mustafa Mahmoud, Mohammed Imad Al-Deen
Format: Book
Language:English
Published: IIUM Press, International Islamic University Malaysia 2017
Subjects:
Online Access:http://irep.iium.edu.my/61967/
http://irep.iium.edu.my/61967/1/61967_Methicillin-resistant%20staphylococcus%20aureus%20%28MRSA%29.pdf
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author Mohamamd Alarosi, Nasreen
Mustafa Mahmoud, Mohammed Imad Al-Deen
author_facet Mohamamd Alarosi, Nasreen
Mustafa Mahmoud, Mohammed Imad Al-Deen
author_sort Mohamamd Alarosi, Nasreen
building IIUM Repository
collection Online Access
description Staphylococcus aureus is a major human pathogen. It causes a wide range of infections in the hospital setting as well as in the community environment. A broad variety of infections, ranging from minor pyodermas to life-threatening infections can be caused by S. aureus. The adaptive power of S. aureus to antibiotics lead to the emergence of methicillin-resistant S. aureus (MRSA) in the early 1960s. The cause of resistance to methicillin is the acquisition of the mecA gene, which is situated on a mobile genetic element, the staphylococcal cassette chromosome mec (SCCmec). Five major variants of SCCmec, types I to V, are distinguished. One of the most important techniques used to investigate the molecular epidemiology of S. aureus is SCCmec typing. This technique has been used to study the evolution of the MRSA and to study their subsequent worldwide dissemination. This research book reviews the literature for previous research on MRSA epidemiology, antibiotic resistance and SCCmec typing methods. It also covers characterization of MRSA isolates obtained from patients attending Tengku Ampuan Afzan Hospital (HTAA) in Kuantan, Pahang, Malaysia.
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format Book
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institution International Islamic University Malaysia
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language English
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publisher IIUM Press, International Islamic University Malaysia
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spelling iium-619672022-01-26T03:13:14Z http://irep.iium.edu.my/61967/ Methicillin-resistant staphylococcus aureus (MRSA): epidemiology and SCCmec typing Mohamamd Alarosi, Nasreen Mustafa Mahmoud, Mohammed Imad Al-Deen R Medicine (General) Staphylococcus aureus is a major human pathogen. It causes a wide range of infections in the hospital setting as well as in the community environment. A broad variety of infections, ranging from minor pyodermas to life-threatening infections can be caused by S. aureus. The adaptive power of S. aureus to antibiotics lead to the emergence of methicillin-resistant S. aureus (MRSA) in the early 1960s. The cause of resistance to methicillin is the acquisition of the mecA gene, which is situated on a mobile genetic element, the staphylococcal cassette chromosome mec (SCCmec). Five major variants of SCCmec, types I to V, are distinguished. One of the most important techniques used to investigate the molecular epidemiology of S. aureus is SCCmec typing. This technique has been used to study the evolution of the MRSA and to study their subsequent worldwide dissemination. This research book reviews the literature for previous research on MRSA epidemiology, antibiotic resistance and SCCmec typing methods. It also covers characterization of MRSA isolates obtained from patients attending Tengku Ampuan Afzan Hospital (HTAA) in Kuantan, Pahang, Malaysia. IIUM Press, International Islamic University Malaysia 2017 Book PeerReviewed application/pdf en http://irep.iium.edu.my/61967/1/61967_Methicillin-resistant%20staphylococcus%20aureus%20%28MRSA%29.pdf Mohamamd Alarosi, Nasreen and Mustafa Mahmoud, Mohammed Imad Al-Deen (2017) Methicillin-resistant staphylococcus aureus (MRSA): epidemiology and SCCmec typing. IIUM Press, International Islamic University Malaysia, Kuala Lumpur, Malaysia. ISBN 978-967-418-734-7 http://iiumpress.iium.edu.my/bookshop
spellingShingle R Medicine (General)
Mohamamd Alarosi, Nasreen
Mustafa Mahmoud, Mohammed Imad Al-Deen
Methicillin-resistant staphylococcus aureus (MRSA): epidemiology and SCCmec typing
title Methicillin-resistant staphylococcus aureus (MRSA): epidemiology and SCCmec typing
title_full Methicillin-resistant staphylococcus aureus (MRSA): epidemiology and SCCmec typing
title_fullStr Methicillin-resistant staphylococcus aureus (MRSA): epidemiology and SCCmec typing
title_full_unstemmed Methicillin-resistant staphylococcus aureus (MRSA): epidemiology and SCCmec typing
title_short Methicillin-resistant staphylococcus aureus (MRSA): epidemiology and SCCmec typing
title_sort methicillin-resistant staphylococcus aureus (mrsa): epidemiology and sccmec typing
topic R Medicine (General)
url http://irep.iium.edu.my/61967/
http://irep.iium.edu.my/61967/
http://irep.iium.edu.my/61967/1/61967_Methicillin-resistant%20staphylococcus%20aureus%20%28MRSA%29.pdf