Understanding the significance variables for fabrication of fish gelatin nanoparticles by Plackett-Burman design
The aim of this experiment is to screen and to understand the process variables on the fabrication of fish gelatin nanoparticles by using quality-design approach. The most influencing process variables were screened by using Plackett-Burman design. Mean particles size, size distribution, and zeta p...
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| Format: | Proceeding Paper |
| Language: | English English |
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IOP Publishing
2017
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| Online Access: | http://irep.iium.edu.my/61900/ http://irep.iium.edu.my/61900/1/FGNP_2018_IOP_Conf._Ser._Mater._Sci._Eng._290_012006.pdf http://irep.iium.edu.my/61900/7/61900_Understanding%20the%20significance%20variables%20for%20fabrication_scopus.pdf |
| _version_ | 1848785758746312704 |
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| author | Subara, Deni Jaswir, Irwandi Al-Khatib, Ma'an Fahmi Rashid Noorbatcha, Ibrahim Ali |
| author_facet | Subara, Deni Jaswir, Irwandi Al-Khatib, Ma'an Fahmi Rashid Noorbatcha, Ibrahim Ali |
| author_sort | Subara, Deni |
| building | IIUM Repository |
| collection | Online Access |
| description | The aim of this experiment is to screen and to understand the process variables on the fabrication of fish gelatin nanoparticles by using quality-design approach. The most influencing process variables were screened by using Plackett-Burman design. Mean particles
size, size distribution, and zeta potential were found in the range 240±9.76 nm, 0.3, and −9 mV, respectively. Statistical results explained that concentration of acetone, pH of solution during precipitation step and volume of cross linker had a most significant effect on particles size of fish gelatin nanoparticles. It was found that, time and chemical consuming is lower than previous research. This study revealed the potential of quality-by design in understanding the effects of process variables on the fish gelatin nanoparticles production. |
| first_indexed | 2025-11-14T16:58:14Z |
| format | Proceeding Paper |
| id | iium-61900 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-14T16:58:14Z |
| publishDate | 2017 |
| publisher | IOP Publishing |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-619002024-05-02T06:26:40Z http://irep.iium.edu.my/61900/ Understanding the significance variables for fabrication of fish gelatin nanoparticles by Plackett-Burman design Subara, Deni Jaswir, Irwandi Al-Khatib, Ma'an Fahmi Rashid Noorbatcha, Ibrahim Ali TP Chemical technology TP248.13 Biotechnology The aim of this experiment is to screen and to understand the process variables on the fabrication of fish gelatin nanoparticles by using quality-design approach. The most influencing process variables were screened by using Plackett-Burman design. Mean particles size, size distribution, and zeta potential were found in the range 240±9.76 nm, 0.3, and −9 mV, respectively. Statistical results explained that concentration of acetone, pH of solution during precipitation step and volume of cross linker had a most significant effect on particles size of fish gelatin nanoparticles. It was found that, time and chemical consuming is lower than previous research. This study revealed the potential of quality-by design in understanding the effects of process variables on the fish gelatin nanoparticles production. IOP Publishing 2017 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/61900/1/FGNP_2018_IOP_Conf._Ser._Mater._Sci._Eng._290_012006.pdf application/pdf en http://irep.iium.edu.my/61900/7/61900_Understanding%20the%20significance%20variables%20for%20fabrication_scopus.pdf Subara, Deni and Jaswir, Irwandi and Al-Khatib, Ma'an Fahmi Rashid and Noorbatcha, Ibrahim Ali (2017) Understanding the significance variables for fabrication of fish gelatin nanoparticles by Plackett-Burman design. In: International Conference on Advances in Manufacturing and Materials Engineering 2017 (ICAMME17), 8-9 August 2017, Kuala Lumpur, Malaysia. http://iopscience.iop.org/article/10.1088/1757-899X/290/1/012006 10.1088/1757-899X/290/1/012006 |
| spellingShingle | TP Chemical technology TP248.13 Biotechnology Subara, Deni Jaswir, Irwandi Al-Khatib, Ma'an Fahmi Rashid Noorbatcha, Ibrahim Ali Understanding the significance variables for fabrication of fish gelatin nanoparticles by Plackett-Burman design |
| title | Understanding the significance variables for fabrication of
fish gelatin nanoparticles by Plackett-Burman design |
| title_full | Understanding the significance variables for fabrication of
fish gelatin nanoparticles by Plackett-Burman design |
| title_fullStr | Understanding the significance variables for fabrication of
fish gelatin nanoparticles by Plackett-Burman design |
| title_full_unstemmed | Understanding the significance variables for fabrication of
fish gelatin nanoparticles by Plackett-Burman design |
| title_short | Understanding the significance variables for fabrication of
fish gelatin nanoparticles by Plackett-Burman design |
| title_sort | understanding the significance variables for fabrication of
fish gelatin nanoparticles by plackett-burman design |
| topic | TP Chemical technology TP248.13 Biotechnology |
| url | http://irep.iium.edu.my/61900/ http://irep.iium.edu.my/61900/ http://irep.iium.edu.my/61900/ http://irep.iium.edu.my/61900/1/FGNP_2018_IOP_Conf._Ser._Mater._Sci._Eng._290_012006.pdf http://irep.iium.edu.my/61900/7/61900_Understanding%20the%20significance%20variables%20for%20fabrication_scopus.pdf |