Evaluation of histological and biomechanical properties on engineered meniscus tissues using sonication decellularization
Sonication decellularization treatment requires proper evaluations on its ability to decellularize meniscus tissue efficiently. This study was done to evaluate the histological and biomechanical properties within meniscus scaffolds. Van Gieson staining was done to evaluate the efficiency of cell re...
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| Format: | Proceeding Paper |
| Language: | English English |
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Institute of Electrical and Electronics Engineers Inc.
2017
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| Online Access: | http://irep.iium.edu.my/61885/ http://irep.iium.edu.my/61885/2/61885_Evaluation%20of%20Histological%20and%20Biomechanical%20Properties_SCOPUS.pdf http://irep.iium.edu.my/61885/17/61885_Evaluation%20of%20Histological%20and%20Biomechanical%20Properties.pdf |
| _version_ | 1848785756138504192 |
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| author | Mohamad Ghazali, Aina Mardhiyah Sha'ban, Munirah Noor Azmi, Azran Azhim |
| author_facet | Mohamad Ghazali, Aina Mardhiyah Sha'ban, Munirah Noor Azmi, Azran Azhim |
| author_sort | Mohamad Ghazali, Aina Mardhiyah |
| building | IIUM Repository |
| collection | Online Access |
| description | Sonication decellularization treatment requires
proper evaluations on its ability to decellularize meniscus tissue efficiently. This study was done to evaluate the histological and biomechanical properties within meniscus scaffolds. Van Gieson staining was done to evaluate the efficiency of cell removal in
meniscus tissues. The consequences of treatment on viscoelastic properties are vital for scaffolds quality and were properly investigated. Picrosirius red and Safranin-O/Fast green staining was carried out to detect extracellular matrix materials (ECM). Sonication decellularization treatment has the ability to
demonstrated complete nuclei removal compare to control
samples as well as maintaining viscoelastic properties, namely stiffness, compression and residual force. Thus, sonication decellularization treatment had successfully produced and prepared a meniscus bioscaffold candidate in which its biomechanical strength is sustained through protection of ECM properties. |
| first_indexed | 2025-11-14T16:58:12Z |
| format | Proceeding Paper |
| id | iium-61885 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-14T16:58:12Z |
| publishDate | 2017 |
| publisher | Institute of Electrical and Electronics Engineers Inc. |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-618852018-06-26T04:24:39Z http://irep.iium.edu.my/61885/ Evaluation of histological and biomechanical properties on engineered meniscus tissues using sonication decellularization Mohamad Ghazali, Aina Mardhiyah Sha'ban, Munirah Noor Azmi, Azran Azhim TP248.13 Biotechnology Sonication decellularization treatment requires proper evaluations on its ability to decellularize meniscus tissue efficiently. This study was done to evaluate the histological and biomechanical properties within meniscus scaffolds. Van Gieson staining was done to evaluate the efficiency of cell removal in meniscus tissues. The consequences of treatment on viscoelastic properties are vital for scaffolds quality and were properly investigated. Picrosirius red and Safranin-O/Fast green staining was carried out to detect extracellular matrix materials (ECM). Sonication decellularization treatment has the ability to demonstrated complete nuclei removal compare to control samples as well as maintaining viscoelastic properties, namely stiffness, compression and residual force. Thus, sonication decellularization treatment had successfully produced and prepared a meniscus bioscaffold candidate in which its biomechanical strength is sustained through protection of ECM properties. Institute of Electrical and Electronics Engineers Inc. 2017-07 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/61885/2/61885_Evaluation%20of%20Histological%20and%20Biomechanical%20Properties_SCOPUS.pdf application/pdf en http://irep.iium.edu.my/61885/17/61885_Evaluation%20of%20Histological%20and%20Biomechanical%20Properties.pdf Mohamad Ghazali, Aina Mardhiyah and Sha'ban, Munirah and Noor Azmi, Azran Azhim (2017) Evaluation of histological and biomechanical properties on engineered meniscus tissues using sonication decellularization. In: 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 201), 11th-15th July 2017, Jeju Island; South Korea. http://ieeexplore.ieee.org/document/8037259/ |
| spellingShingle | TP248.13 Biotechnology Mohamad Ghazali, Aina Mardhiyah Sha'ban, Munirah Noor Azmi, Azran Azhim Evaluation of histological and biomechanical properties on engineered meniscus tissues using sonication decellularization |
| title | Evaluation of histological and biomechanical properties on
engineered meniscus tissues using sonication decellularization |
| title_full | Evaluation of histological and biomechanical properties on
engineered meniscus tissues using sonication decellularization |
| title_fullStr | Evaluation of histological and biomechanical properties on
engineered meniscus tissues using sonication decellularization |
| title_full_unstemmed | Evaluation of histological and biomechanical properties on
engineered meniscus tissues using sonication decellularization |
| title_short | Evaluation of histological and biomechanical properties on
engineered meniscus tissues using sonication decellularization |
| title_sort | evaluation of histological and biomechanical properties on
engineered meniscus tissues using sonication decellularization |
| topic | TP248.13 Biotechnology |
| url | http://irep.iium.edu.my/61885/ http://irep.iium.edu.my/61885/ http://irep.iium.edu.my/61885/2/61885_Evaluation%20of%20Histological%20and%20Biomechanical%20Properties_SCOPUS.pdf http://irep.iium.edu.my/61885/17/61885_Evaluation%20of%20Histological%20and%20Biomechanical%20Properties.pdf |