Microencapsulation of fish oil using supercritical antisolvent process
In order to improve the encapsulation process, a newly supercritical antisolvent process was developed to encapsulate fish oil using hydroxypropyl methyl cellulose as a polymer. Three factors, namely, temperature, pressure, and feed emulsion rate were optimized using response surface methodology. Th...
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| Format: | Article |
| Language: | English English |
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Elsevier
2017
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| Online Access: | http://irep.iium.edu.my/61760/ http://irep.iium.edu.my/61760/1/JFDA-Fahim-Zaidul-2017.pdf http://irep.iium.edu.my/61760/7/61760-Microencapsulation%20of%20fish%20oil%20using%20supercritical%20antisolvent%20process-SCOPUS.pdf |
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| author | Karim, Fahim Tamzeedul Ghafoor, Kashif Ferdosh, Sahena Al-Juhaımı,, Fahad Y.I. Ali, Md Eaqub Yunus, Kamaruzzaman Hamed, Mir Hoseini Islam., Ashraful M.A Asif, Muhammad Kamran Sarker, Md Zaidul Islam |
| author_facet | Karim, Fahim Tamzeedul Ghafoor, Kashif Ferdosh, Sahena Al-Juhaımı,, Fahad Y.I. Ali, Md Eaqub Yunus, Kamaruzzaman Hamed, Mir Hoseini Islam., Ashraful M.A Asif, Muhammad Kamran Sarker, Md Zaidul Islam |
| author_sort | Karim, Fahim Tamzeedul |
| building | IIUM Repository |
| collection | Online Access |
| description | In order to improve the encapsulation process, a newly supercritical antisolvent process was developed to encapsulate fish oil using hydroxypropyl methyl cellulose as a polymer. Three factors, namely, temperature, pressure, and feed emulsion rate were optimized using response surface methodology. The suitability of the model for predicting the opti-mum response value was evaluated at the conditions of temperature at 60 C, pressure at 150 bar, and feed rate at 1.36 mL/min. At the optimum conditions, particle size of 58.35 mm was obtained. The surface morphology of the micronized fish oil was also evaluated using field emission scanning electron microscopy where it showed that particles formed spherical structures with no internal voids. Moreover, in vitro release of oil showed that there are significant differences of release percentage of oil between the formulations and the results proved that there was a significant decrease in the in vitro release of oil from the powder when the polymer concentration was high. |
| first_indexed | 2025-11-14T16:57:46Z |
| format | Article |
| id | iium-61760 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-14T16:57:46Z |
| publishDate | 2017 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-617602018-02-01T08:49:07Z http://irep.iium.edu.my/61760/ Microencapsulation of fish oil using supercritical antisolvent process Karim, Fahim Tamzeedul Ghafoor, Kashif Ferdosh, Sahena Al-Juhaımı,, Fahad Y.I. Ali, Md Eaqub Yunus, Kamaruzzaman Hamed, Mir Hoseini Islam., Ashraful M.A Asif, Muhammad Kamran Sarker, Md Zaidul Islam Q Science (General) In order to improve the encapsulation process, a newly supercritical antisolvent process was developed to encapsulate fish oil using hydroxypropyl methyl cellulose as a polymer. Three factors, namely, temperature, pressure, and feed emulsion rate were optimized using response surface methodology. The suitability of the model for predicting the opti-mum response value was evaluated at the conditions of temperature at 60 C, pressure at 150 bar, and feed rate at 1.36 mL/min. At the optimum conditions, particle size of 58.35 mm was obtained. The surface morphology of the micronized fish oil was also evaluated using field emission scanning electron microscopy where it showed that particles formed spherical structures with no internal voids. Moreover, in vitro release of oil showed that there are significant differences of release percentage of oil between the formulations and the results proved that there was a significant decrease in the in vitro release of oil from the powder when the polymer concentration was high. Elsevier 2017-07 Article PeerReviewed application/pdf en http://irep.iium.edu.my/61760/1/JFDA-Fahim-Zaidul-2017.pdf application/pdf en http://irep.iium.edu.my/61760/7/61760-Microencapsulation%20of%20fish%20oil%20using%20supercritical%20antisolvent%20process-SCOPUS.pdf Karim, Fahim Tamzeedul and Ghafoor, Kashif and Ferdosh, Sahena and Al-Juhaımı,, Fahad Y.I. and Ali, Md Eaqub and Yunus, Kamaruzzaman and Hamed, Mir Hoseini and Islam., Ashraful M.A and Asif, Muhammad Kamran and Sarker, Md Zaidul Islam (2017) Microencapsulation of fish oil using supercritical antisolvent process. Journal of Food and Drug Analysis, 25 (3). pp. 654-666. https://ac.els-cdn.com/S1021949817300297/1-s2.0-S1021949817300297-main.pdf?_tid=54f1f5a0-0723-11e8-bae8-00000aacb360&acdnat=1517471076_3c33f12d87750eeadd1b8b7346288e4b 10.1016/j.jfda.2016.11.017 |
| spellingShingle | Q Science (General) Karim, Fahim Tamzeedul Ghafoor, Kashif Ferdosh, Sahena Al-Juhaımı,, Fahad Y.I. Ali, Md Eaqub Yunus, Kamaruzzaman Hamed, Mir Hoseini Islam., Ashraful M.A Asif, Muhammad Kamran Sarker, Md Zaidul Islam Microencapsulation of fish oil using supercritical antisolvent process |
| title | Microencapsulation of fish oil using supercritical antisolvent process |
| title_full | Microencapsulation of fish oil using supercritical antisolvent process |
| title_fullStr | Microencapsulation of fish oil using supercritical antisolvent process |
| title_full_unstemmed | Microencapsulation of fish oil using supercritical antisolvent process |
| title_short | Microencapsulation of fish oil using supercritical antisolvent process |
| title_sort | microencapsulation of fish oil using supercritical antisolvent process |
| topic | Q Science (General) |
| url | http://irep.iium.edu.my/61760/ http://irep.iium.edu.my/61760/ http://irep.iium.edu.my/61760/ http://irep.iium.edu.my/61760/1/JFDA-Fahim-Zaidul-2017.pdf http://irep.iium.edu.my/61760/7/61760-Microencapsulation%20of%20fish%20oil%20using%20supercritical%20antisolvent%20process-SCOPUS.pdf |