Formulation and characterization of cosmetic cream incorporating piper Betle Linn. extract

INTRODUCTION: Piper betle Linn. is an evergreen and perennial plant with glossy heart-shaped leaves which contains various biologically active compounds. Hydroxychavicol is a phenolic compound found in Piper betle leaves which exhibits many potential biological activities such as antimicrobial, anti...

Full description

Bibliographic Details
Main Authors: Hanif, Nadzira, Doolaanea, Abd Almonem, Ab. Hadi, Hazrina
Format: Proceeding Paper
Language:English
Published: 2017
Subjects:
Online Access:http://irep.iium.edu.my/61757/
http://irep.iium.edu.my/61757/17/61757_Formulation%20and%20Characterization%20of%20Cosmetic%20Cream_complete.pdf
_version_ 1848785728208633856
author Hanif, Nadzira
Doolaanea, Abd Almonem
Ab. Hadi, Hazrina
author_facet Hanif, Nadzira
Doolaanea, Abd Almonem
Ab. Hadi, Hazrina
author_sort Hanif, Nadzira
building IIUM Repository
collection Online Access
description INTRODUCTION: Piper betle Linn. is an evergreen and perennial plant with glossy heart-shaped leaves which contains various biologically active compounds. Hydroxychavicol is a phenolic compound found in Piper betle leaves which exhibits many potential biological activities such as antimicrobial, antioxidant, anti-inflammatory and anti-tyrosinase.OBJECTIVES: The study aimed to formulate cosmetic cream incorporating Piper betle extract and to characterize the developed cream.METHODS: The cosmetic cream containing 0.02% Piper betle extract was developed by incorporating three phase ingredients include aqueous phase (75.2%), oil phase (20.8%) and cooling phase (4.0%). O/W emulsion was prepared by adding aqueous phase into oil phase through a combination process of heating up to 75℃ and homogenization at 3500 rpm. The cream formulation was characterized for organoleptic properties, pH, particle size, zeta potential, rheological behaviour and microbial limit test.RESULTS: For organoleptic properties, the cream has an off white color, pleasant odour, smooth texture and no phase separation. The cream formulation has a pH value of 5.39 ± 0.03 which was near to skin pH (4.5-5.5), smaller particle size of 3.73 ± 0.01 µm and polydispersity index of 0.56 ± 0.11, negatively zeta potential of -57.53 ± 1.47 mV and exhibited non-Newtonian behavior in which viscosity decreases when shear rate increases. The cream has no growth of viable microorganisms, yeasts and fungi.CONCLUSION: Based on physical characterization, the cream containing 0.02% Piper betle extract is regarded as a stable formulation with acceptable organoleptic properties.Keywords: Characterization, cream, formulation, oil in water emulsion, Piper betle Linn.
first_indexed 2025-11-14T16:57:45Z
format Proceeding Paper
id iium-61757
institution International Islamic University Malaysia
institution_category Local University
language English
last_indexed 2025-11-14T16:57:45Z
publishDate 2017
recordtype eprints
repository_type Digital Repository
spelling iium-617572018-06-29T03:27:20Z http://irep.iium.edu.my/61757/ Formulation and characterization of cosmetic cream incorporating piper Betle Linn. extract Hanif, Nadzira Doolaanea, Abd Almonem Ab. Hadi, Hazrina RS Pharmacy and materia medica INTRODUCTION: Piper betle Linn. is an evergreen and perennial plant with glossy heart-shaped leaves which contains various biologically active compounds. Hydroxychavicol is a phenolic compound found in Piper betle leaves which exhibits many potential biological activities such as antimicrobial, antioxidant, anti-inflammatory and anti-tyrosinase.OBJECTIVES: The study aimed to formulate cosmetic cream incorporating Piper betle extract and to characterize the developed cream.METHODS: The cosmetic cream containing 0.02% Piper betle extract was developed by incorporating three phase ingredients include aqueous phase (75.2%), oil phase (20.8%) and cooling phase (4.0%). O/W emulsion was prepared by adding aqueous phase into oil phase through a combination process of heating up to 75℃ and homogenization at 3500 rpm. The cream formulation was characterized for organoleptic properties, pH, particle size, zeta potential, rheological behaviour and microbial limit test.RESULTS: For organoleptic properties, the cream has an off white color, pleasant odour, smooth texture and no phase separation. The cream formulation has a pH value of 5.39 ± 0.03 which was near to skin pH (4.5-5.5), smaller particle size of 3.73 ± 0.01 µm and polydispersity index of 0.56 ± 0.11, negatively zeta potential of -57.53 ± 1.47 mV and exhibited non-Newtonian behavior in which viscosity decreases when shear rate increases. The cream has no growth of viable microorganisms, yeasts and fungi.CONCLUSION: Based on physical characterization, the cream containing 0.02% Piper betle extract is regarded as a stable formulation with acceptable organoleptic properties.Keywords: Characterization, cream, formulation, oil in water emulsion, Piper betle Linn. 2017 Proceeding Paper NonPeerReviewed application/pdf en http://irep.iium.edu.my/61757/17/61757_Formulation%20and%20Characterization%20of%20Cosmetic%20Cream_complete.pdf Hanif, Nadzira and Doolaanea, Abd Almonem and Ab. Hadi, Hazrina (2017) Formulation and characterization of cosmetic cream incorporating piper Betle Linn. extract. In: Malaysia Pharmaceutical Society Conference 2017, 3-5 November, 2017, Penang, Malaysia.
spellingShingle RS Pharmacy and materia medica
Hanif, Nadzira
Doolaanea, Abd Almonem
Ab. Hadi, Hazrina
Formulation and characterization of cosmetic cream incorporating piper Betle Linn. extract
title Formulation and characterization of cosmetic cream incorporating piper Betle Linn. extract
title_full Formulation and characterization of cosmetic cream incorporating piper Betle Linn. extract
title_fullStr Formulation and characterization of cosmetic cream incorporating piper Betle Linn. extract
title_full_unstemmed Formulation and characterization of cosmetic cream incorporating piper Betle Linn. extract
title_short Formulation and characterization of cosmetic cream incorporating piper Betle Linn. extract
title_sort formulation and characterization of cosmetic cream incorporating piper betle linn. extract
topic RS Pharmacy and materia medica
url http://irep.iium.edu.my/61757/
http://irep.iium.edu.my/61757/17/61757_Formulation%20and%20Characterization%20of%20Cosmetic%20Cream_complete.pdf