Effect of thymol and carvacrol, the major components of thymus capitatus on the growth of pseudomonas aeruginosa
his study was designed to evaluate the antibacterial activity of Thymus capitatus and two of its major components namely thymol and carvacrol. The dried leaves were extracted using soxhlet apparatus. Thymol and carvacrol were isolated using normal phase column chromatography. The antibacterial activ...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English English |
| Published: |
Journal of Pure and Applied Microbiology
2016
|
| Subjects: | |
| Online Access: | http://irep.iium.edu.my/61528/ http://irep.iium.edu.my/61528/7/61528_Effect%20of%20Thymol%20and%20Carvacrol_article.pdf http://irep.iium.edu.my/61528/13/61528_Effect%20of%20Thymol%20and%20Carvacrol_scopus.pdf |
| _version_ | 1848785690357137408 |
|---|---|
| author | Althunibat, Osama Yousef Qaralleh, Haitham Abboud, Muayad Khleifat, Khaled Majali, Ibrahim S. Darnis, Deny Susanti Aldal'In, Hammad Khalifeh H. Yassin Ahmed Al-dalin, Sati |
| author_facet | Althunibat, Osama Yousef Qaralleh, Haitham Abboud, Muayad Khleifat, Khaled Majali, Ibrahim S. Darnis, Deny Susanti Aldal'In, Hammad Khalifeh H. Yassin Ahmed Al-dalin, Sati |
| author_sort | Althunibat, Osama Yousef |
| building | IIUM Repository |
| collection | Online Access |
| description | his study was designed to evaluate the antibacterial activity of Thymus capitatus and two of its major components namely thymol and carvacrol. The dried leaves were extracted using soxhlet apparatus. Thymol and carvacrol were isolated using normal phase column chromatography. The antibacterial activity of the leaves extract, thymol and carvacrol were estimated using agar disc diffusion and broth dilution methods against four bacterial strains. The leaves extract was found to show a broad spectrum of antibacterial activity against all the tested bacterial strains. Pseudomonas aeruginosa was the most sensitive bacteria. The purified compounds exhibited relatively stronger antibacterial activity than the extract. Thymol fraction exhibited stronger antibacterial activity than carvacrol. Thymol fraction exhibited MIC values ranging from 0.005 – 0.008 mg/mL while carvacrol fraction exhibited MIC values ranging from 0.007 – 0.008 mg/mL. |
| first_indexed | 2025-11-14T16:57:09Z |
| format | Article |
| id | iium-61528 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-14T16:57:09Z |
| publishDate | 2016 |
| publisher | Journal of Pure and Applied Microbiology |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-615282018-07-11T00:28:07Z http://irep.iium.edu.my/61528/ Effect of thymol and carvacrol, the major components of thymus capitatus on the growth of pseudomonas aeruginosa Althunibat, Osama Yousef Qaralleh, Haitham Abboud, Muayad Khleifat, Khaled Majali, Ibrahim S. Darnis, Deny Susanti Aldal'In, Hammad Khalifeh H. Yassin Ahmed Al-dalin, Sati QD Chemistry his study was designed to evaluate the antibacterial activity of Thymus capitatus and two of its major components namely thymol and carvacrol. The dried leaves were extracted using soxhlet apparatus. Thymol and carvacrol were isolated using normal phase column chromatography. The antibacterial activity of the leaves extract, thymol and carvacrol were estimated using agar disc diffusion and broth dilution methods against four bacterial strains. The leaves extract was found to show a broad spectrum of antibacterial activity against all the tested bacterial strains. Pseudomonas aeruginosa was the most sensitive bacteria. The purified compounds exhibited relatively stronger antibacterial activity than the extract. Thymol fraction exhibited stronger antibacterial activity than carvacrol. Thymol fraction exhibited MIC values ranging from 0.005 – 0.008 mg/mL while carvacrol fraction exhibited MIC values ranging from 0.007 – 0.008 mg/mL. Journal of Pure and Applied Microbiology 2016-03 Article NonPeerReviewed application/pdf en http://irep.iium.edu.my/61528/7/61528_Effect%20of%20Thymol%20and%20Carvacrol_article.pdf application/pdf en http://irep.iium.edu.my/61528/13/61528_Effect%20of%20Thymol%20and%20Carvacrol_scopus.pdf Althunibat, Osama Yousef and Qaralleh, Haitham and Abboud, Muayad and Khleifat, Khaled and Majali, Ibrahim S. and Darnis, Deny Susanti and Aldal'In, Hammad Khalifeh H. and Yassin Ahmed Al-dalin, Sati (2016) Effect of thymol and carvacrol, the major components of thymus capitatus on the growth of pseudomonas aeruginosa. Journal of Pure and gyApplied Microbiology, 10 (1). pp. 367-374. ISSN 0973-7510 (In Press) http://microbiologyjournal.org/jmabsarchive.php?vol=10&issue=1 |
| spellingShingle | QD Chemistry Althunibat, Osama Yousef Qaralleh, Haitham Abboud, Muayad Khleifat, Khaled Majali, Ibrahim S. Darnis, Deny Susanti Aldal'In, Hammad Khalifeh H. Yassin Ahmed Al-dalin, Sati Effect of thymol and carvacrol, the major components of thymus capitatus on the growth of pseudomonas aeruginosa |
| title | Effect of thymol and carvacrol, the major components of
thymus capitatus on the growth of pseudomonas aeruginosa |
| title_full | Effect of thymol and carvacrol, the major components of
thymus capitatus on the growth of pseudomonas aeruginosa |
| title_fullStr | Effect of thymol and carvacrol, the major components of
thymus capitatus on the growth of pseudomonas aeruginosa |
| title_full_unstemmed | Effect of thymol and carvacrol, the major components of
thymus capitatus on the growth of pseudomonas aeruginosa |
| title_short | Effect of thymol and carvacrol, the major components of
thymus capitatus on the growth of pseudomonas aeruginosa |
| title_sort | effect of thymol and carvacrol, the major components of
thymus capitatus on the growth of pseudomonas aeruginosa |
| topic | QD Chemistry |
| url | http://irep.iium.edu.my/61528/ http://irep.iium.edu.my/61528/ http://irep.iium.edu.my/61528/7/61528_Effect%20of%20Thymol%20and%20Carvacrol_article.pdf http://irep.iium.edu.my/61528/13/61528_Effect%20of%20Thymol%20and%20Carvacrol_scopus.pdf |