Isolation and identification of flavonoids from Tetracera indica Merr. (Dilleniaceae) leaves
Leaves of Tetracera indica are used in traditional medicine for the treatment of diabetes mellitus in Malaysia. This study was aimed at investigating the phytochemical constituents present in T. indica leaves which may be responsible for the antidiabetic effect of the plant’s leaves. Crude methanoli...
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| Format: | Proceeding Paper |
| Language: | English |
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2016
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| Online Access: | http://irep.iium.edu.my/61096/ http://irep.iium.edu.my/61096/18/61096_Isolation%20and%20identification%20of%20flavonoids_complete.pdf |
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| author | Ahmed, Qamar Uddin Alhassan, MA Hasan, Md. Mahmudul (Stu) Khatib, Alfi Sarian, Murni Nazira Latip, Jalifah |
| author_facet | Ahmed, Qamar Uddin Alhassan, MA Hasan, Md. Mahmudul (Stu) Khatib, Alfi Sarian, Murni Nazira Latip, Jalifah |
| author_sort | Ahmed, Qamar Uddin |
| building | IIUM Repository |
| collection | Online Access |
| description | Leaves of Tetracera indica are used in traditional medicine for the treatment of diabetes mellitus in Malaysia. This study was aimed at investigating the phytochemical constituents present in T. indica leaves which may be responsible for the antidiabetic effect of the plant’s leaves. Crude methanolic extract from the leaves of T. indica was separated and purified by column chromatography of silica gel, ODS and sephadex LH-20. The structures of the isolated compounds were identified and elucidated by UV, 1H-NMR, 13C-NMR and MS spectroscopic techniques. Four flavonoids were isolated from the leaves of T. indica, and these compounds were identified as follows: 5,7-dihydroxy-8-methoxyflavone (wogonin), 5,7,8-trihydroxyflavone (norwogonin), quercetin and 5-Hydroxy-7-methoxyflavone (tectochrysin). The three compounds i.e. norwogonin, quercetin and tectochrysin are being reported for the first time from T. indica leaves. Keywords: Tetracera indica, flavonoids, diabetes mellitus |
| first_indexed | 2025-11-14T16:55:52Z |
| format | Proceeding Paper |
| id | iium-61096 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T16:55:52Z |
| publishDate | 2016 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-610962019-01-04T03:06:39Z http://irep.iium.edu.my/61096/ Isolation and identification of flavonoids from Tetracera indica Merr. (Dilleniaceae) leaves Ahmed, Qamar Uddin Alhassan, MA Hasan, Md. Mahmudul (Stu) Khatib, Alfi Sarian, Murni Nazira Latip, Jalifah Q Science (General) QD Chemistry Leaves of Tetracera indica are used in traditional medicine for the treatment of diabetes mellitus in Malaysia. This study was aimed at investigating the phytochemical constituents present in T. indica leaves which may be responsible for the antidiabetic effect of the plant’s leaves. Crude methanolic extract from the leaves of T. indica was separated and purified by column chromatography of silica gel, ODS and sephadex LH-20. The structures of the isolated compounds were identified and elucidated by UV, 1H-NMR, 13C-NMR and MS spectroscopic techniques. Four flavonoids were isolated from the leaves of T. indica, and these compounds were identified as follows: 5,7-dihydroxy-8-methoxyflavone (wogonin), 5,7,8-trihydroxyflavone (norwogonin), quercetin and 5-Hydroxy-7-methoxyflavone (tectochrysin). The three compounds i.e. norwogonin, quercetin and tectochrysin are being reported for the first time from T. indica leaves. Keywords: Tetracera indica, flavonoids, diabetes mellitus 2016 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/61096/18/61096_Isolation%20and%20identification%20of%20flavonoids_complete.pdf Ahmed, Qamar Uddin and Alhassan, MA and Hasan, Md. Mahmudul (Stu) and Khatib, Alfi and Sarian, Murni Nazira and Latip, Jalifah (2016) Isolation and identification of flavonoids from Tetracera indica Merr. (Dilleniaceae) leaves. In: 2nd International Conference on Industrial Pharmacy (ICIP 2016), 15th-16th Aug. 2016, Kuantan, Pahang. (Unpublished) http://www.iium.edu.my/icip2016/downloads/programmebook.pdf |
| spellingShingle | Q Science (General) QD Chemistry Ahmed, Qamar Uddin Alhassan, MA Hasan, Md. Mahmudul (Stu) Khatib, Alfi Sarian, Murni Nazira Latip, Jalifah Isolation and identification of flavonoids from Tetracera indica Merr. (Dilleniaceae) leaves |
| title | Isolation and identification of flavonoids from Tetracera indica Merr. (Dilleniaceae) leaves |
| title_full | Isolation and identification of flavonoids from Tetracera indica Merr. (Dilleniaceae) leaves |
| title_fullStr | Isolation and identification of flavonoids from Tetracera indica Merr. (Dilleniaceae) leaves |
| title_full_unstemmed | Isolation and identification of flavonoids from Tetracera indica Merr. (Dilleniaceae) leaves |
| title_short | Isolation and identification of flavonoids from Tetracera indica Merr. (Dilleniaceae) leaves |
| title_sort | isolation and identification of flavonoids from tetracera indica merr. (dilleniaceae) leaves |
| topic | Q Science (General) QD Chemistry |
| url | http://irep.iium.edu.my/61096/ http://irep.iium.edu.my/61096/ http://irep.iium.edu.my/61096/18/61096_Isolation%20and%20identification%20of%20flavonoids_complete.pdf |