Photo activated bacterial DNA-binding active Rutaceous alkaloids from Glycosmis pentaphylla (Retz.) DC. and Ruta angustifolia (L.) Pers.

QR Code

Photo activated bacterial DNA-binding active Rutaceous alkaloids from Glycosmis pentaphylla (Retz.) DC. and Ruta angustifolia (L.) Pers.

Arborine, a quinazoline and graveoline, a 4-quinolone are the antimicrobial active Rutaceous alkaloids isolated from Glycosmis pentaphylla and Ruta angustifolia, respectively. Both alkaloids possess chromophore with a few structural similarities with the pharmacophore of 4-quinolone antimicrobial a...

Full description

Bibliographic Details
Main Authors:	Md Taib, Nurhaya, Mohd Kamal, Laina Zarisa, Mohd Hassan, Norazian, Khin Soe, May
Format:	Proceeding Paper
Language:	English English English
Published:	University of Malaya 2017
Subjects:	QD Chemistry QR Microbiology RS403 Materia Medica-Pharmaceutical Chemistry
Online Access:	http://irep.iium.edu.my/60902/ http://irep.iium.edu.my/60902/1/IMFSC2017-1.pdf http://irep.iium.edu.my/60902/2/CERT.-AZIAN.pdf http://irep.iium.edu.my/60902/3/POSTER.pdf

Similar Items

Arborine, a quinazolin-4-one antimicrobial alkaloid from Glycosmis pentaphylla (Retz.) DC
by: Md Taib, Nurhaya, et al.
Published: (2010)

Bioautographic screening for natural quinolone antimicrobial agents from Glycosmis pentaphylla (Retz.) DC., Ruta angustifolia (L.) Pers. and Lunasia amara Blanco
by: Md Taib, Nurhaya, et al.
Published: (2009)

Graveoline from Ruta angustifolia (L.) Pers. and its antimicrobial synergistic potential in erythromycin or vancomycin combinations = Graveolin daripada Ruta angustifolia (L.) Pers. dan potensi sinergistik antimikrobnya dalam gabungan erithromicin atau vancomicin
by: Mohd Kamal, Laina Zarisa, et al.
Published: (2018)

Bioassay-guided isolation of antimicrobial active alkaloids from Ruta angustifolia (L.) Pers
by: Mohd Kamal, Laina Zarisa, et al.
Published: (2010)

Antimicrobial activity of extracts and alkaloids from callus and shoot cultures of Ruta angustifolia (L.) Pers
by: Mohd Hassan, Norazian, et al.
Published: (2012)

Determination of octanol-water partition coefficients of anti-microbial alkaloids from Glycosmis pentaphylla (Retz) DC
by: Ahmad, Kausar, et al.
Published: (2010)

Graveoline, an antimicrobial activ alkaloid from Ruta angustifolia (L.) Pers. and its in vitro antimicrobial combination effects with either erythromycin or vancomycin
by: Mohd Kamal, Laina Zarisa, et al.
Published: (2017)

Antioxidant and antibacterial activities of Ruta angustifolia extract
by: Muhammad Shuib, Nur Azfa, et al.
Published: (2015)

Antifungal Activities Of Three Alkaloids From Ruta Angustifolia (L.) Pers. Against ATCC Susceptible Strains Of Candida Albicans And Candida Glabrata
by: Kamal, Laina Zarisa Mohd
Published: (2019)

Graveoline from Ruta angustifolia (L.) Pers. and its antimicrobial synergistic potential in erythromycin or vancomycin combinations
by: Laina Zarisa Mohd Kamal,, et al.
Published: (2018)

Isolation, characterization and cytotoxic activity of arborinine from glycosmis pentaphylla (Retz.) DC. on human mammary gland adenocarcinoma (MCF7) cell line
by: Mohd Hussain, Nurlaili Najmi, et al.
Published: (2015)

Alkaloids from alphonsea elliptica barks and their biological activities
by: Obaid, Ahmed Kareem, et al.
Published: (2018)

Natural quinolone antimicrobial agents from Malaysian Rutaceous species
by: Mohd Hassan, Norazian, et al.
Published: (2011)

Natural quinolone antimicrobial agents from Malaysian Rutaceous species
by: Mohd Hassan, Norazian, et al.
Published: (2010)

Arborinine from Glycosmis Pentaphylla (retz.) DC induces apoptosis through activation of Caspase-3/7 in human mammary gland Adenocarcinoma (MCF-7) cell line
by: Mohd Hussain, Nurlaili Najmie, et al.
Published: (2016)

Antioxidant and antibacterial activities of ruta angustifolia extract
by: Shuib, Nur Azra, et al.
Published: (2015)

Carotenoid biosynthesis in the leaves, shoot cultures and callus cultures of ruta angustifolia
by: Mohd Zaifuddin, Fatimah Azzahra, et al.
Published: (2014)

The effects of elicitors on lutein and zeaxanthin accumulation in in vitro cultures of Ruta angustifolia (L.) Pers.
by: Mohd Hassan, Norazian, et al.
Published: (2015)

Antiproliferative activities of chalepin and rutamarin isolated from Ruta angustifolia on selected cancer cell lines / Musa Isah Fakai
by: Musa Isah , Fakai
Published: (2019)

Antioxidant activities of Dialium indum L. fruit and gas chromatography-mass spectrometry (GC-MS) of the active fractions
by: Osman, Muhamad Faris, et al.
Published: (2018)

Identification of alkaloid compounds arborinine and graveoline from Ruta angustifolia L. Pers for their antifungal potential against isocitrate lyase ICL1 gene of candida albicans
by: Mohd Kamal, Laina Zarisa, et al.
Published: (2021)

Insights on the synthesis of asymmetric curcumin derivatives and their biological activities
by: Rullah, Malaysia, et al.
Published: (2019)

Alkaloids and sulphur-containing amides from glycosmis citrifolia and glycosmis elongata
by: Mawardi Rahmani,, et al.
Published: (2010)

Alkaloids and sulphur-containing amides from Glycosmis citrifolia and Glycosmis elongata
by: Rahmani, Mawardi, et al.
Published: (2010)

In vitro antioxidant activities and gas-chromatography-mass spectrometry (GC-MS) analysis of antioxidant active fractions of Dialium indum var. indum L. fruit
by: Osman, Muhammad Faris, et al.
Published: (2017)

Enzyme inhibitory and antioxidant investigations of Tetracera macrophylla Vall. and Entada spiralis Ridl. and isolation of active principles
by: Opeyemi Roheem, Fatimah, et al.
Published: (2017)

Synthesis and effects of oxadiazole derivatives on tyrosinase activity and human SK-MEL-28 malignant melanoma cells
by: Mohd Aluwi, Mohd Fadhlizil Fasihi, et al.
Published: (2016)

Inhibition of prostaglandin E-2 production by synthetic minor prenylated chalcones and flavonoids: Synthesis, biological activity, crystal structure, and in silico evaluation
by: Kamal, Rullah, et al.
Published: (2014)

Nitric oxide inhibitory activity and antioxidant evaluations of 2-benzoyl-6-benzylidenecyclohexanone analogs, a novel series of curcuminoid and diarylpentanoid derivatives
by: Leong, Sze Wei, et al.
Published: (2015)

Chemical profile, total phenolic content, DPPH free radical scavenging and α-lucosidase inhibitory activities of cosmos caudatus kunth leaves
by: Wan Ahmad, Wan Nadilah, et al.
Published: (2018)

Chemical profile, total phenolic content, DPPH free radical scavenging and α-glucosidase inhibitory activities of cosmos caudatus kunth leaves
by: Wan Ahmad, Wan Nadilah, et al.
Published: (2018)

Determination of carotenoid(s) composition in intact plant, callus and shoot cultures of Ruta angustifolia (L.) Pers.
by: Mohd. Zaifuddin, Fatimah Azzah, et al.
Published: (2011)

Flavonoids from Tetracera indica Merr. inhibit adipocyte differentiation and exert glucose uptake activities in 3T3-L1 adipocyte cells
by: Ahmed, Qamar Uddin, et al.
Published: (2016)

Inhibition of nitric oxide and prostaglandin E2 production by pyrrolylated-chalcones: synthesis, biological activity, crystal structure analysis, and molecular docking studies
by: Mohd Faudzi, Siti Munirah, et al.
Published: (2020)

Molecular characterization, biological activity, and in silico study of 2-(3,4-dimethoxyphenyl)-3-(4-fluorophenyl)-6-methoxy-4H-chromen-4-one as a novel selective COX-2 inhibitor
by: Rullah, Kamal, et al.
Published: (2015)

Hits-to-lead optimization of the natural compound 2,4,6-trihydroxy-3-geranyl-acetophenone (tHGA) as a potent LOX Inhibitor: synthesis, structure-activity relationship (SAR) study and computational assignment
by: Ng, Chean Hui, et al.
Published: (2018)

Carotenoids of Capsicum fruits: pigment profile and health-promoting functional-attributes
by: Mohd Hassan, Norazian, et al.
Published: (2019)

Two new acridone alkaloids from Glycosmis macrantha
by: Yahayu, Maizatul Akmal, et al.
Published: (2011)

In vivo anxiolytic and in vitro anti-inflammatory activities of water-soluble extract (WSE) of Nigella sativa (L.) seeds
by: Mohammed Babar, Zahir Uddin, et al.
Published: (2019)

Effects of methyl jasmonate elicitation on growth and lutein content in microshoot cultures of Ruta angustifolia (L.) Pers
by: Mohd Hassan, Norazian, et al.
Published: (2015)