In vitro evaluation of porcupine bezoar extracts as anticancer agent on A549 -A preliminary study

QR Code

In vitro evaluation of porcupine bezoar extracts as anticancer agent on A549 -A preliminary study

Porcupine bezoar (PB) was reported to possess medicinal properties in old medical manuscript. However, its potential as anticancer agent on human lung cancer cells (A549) is not yet studied. In present study, porcupine bezoar was tested to observe its ability in inhibiting cell growth of cancer cell...

Full description

Bibliographic Details
Main Authors:	Firus Khan, Al'aina Yuhainis, Mohd Nasir, Mohd Hamzah, Jalal, Tara Kamal, Razali, Shakirah, Hassan, Habibah, Abdullah Asuhaimi, Faizah, Abdul Wahab, Ridhwan
Format:	Article
Language:	English
Published:	Juniper Publishers 2017
Subjects:	RM Therapeutics. Pharmacology
Online Access:	http://irep.iium.edu.my/60815/ http://irep.iium.edu.my/60815/1/a549.pdf

Similar Items

Porcupine bezoar exhibit as anti-cancer activities on human breast adenocarcinoma cells (MCF-7)
by: Firus Khan, Al'aina Yuhainis, et al.
Published: (2016)

Porcupine bezoar exhibit cell cycle arrest through inhibiting cyclin /CDK1 complex and apoptosis mitochondria mediated dependent pathway in A549 cells
by: Firus Khan, Al'aina Yuhainis, et al.
Published: (2016)

Hystrix brachyura bezoar characterization, antioxidant activity screening, and anticancer activity on melanoma cells (A375): a preliminary study
by: Firus Khan, Al'aina Yuhanis, et al.
Published: (2019)

Investigation of porcupine bezoar extract combined with electroporation on HeLa cell
by: Azizulkarim, Azra Hazwanie, et al.
Published: (2019)

Porcupine bezoar: in vitro antioxidant and anti-proliferative effects
by: Abdullah Asuhaimi, Faizah, et al.
Published: (2017)

In-vitro evaluation of porcupine bezoar extracts (PBE) as anti-cancer agent on HeLa cell line – A preliminary study
by: Azizulkarim, Azra Hazwanie, et al.
Published: (2018)

Anticancer activity of grassy Hystrix brachyura bezoar and its mechanisms of action: An in vitro and in vivo based study
by: Khan, Al’aina Yuhainis Firus, et al.
Published: (2019)

Anticancer activity of grassy Hystrix brachyura bezoar and its mechanisms of action: An in vitro and in vivo based study
by: Firus Khan, Al’aina Yuhainis, et al.
Published: (2019)

Evaluating anticancer activity of plant-mediated synthesized iron oxide nanoparticles using Punica Granatum fruit peel extract
by: Yusefi, Mostafa, et al.
Published: (2020)

Preliminary screening of anticancer activity using underutilized fruit Baccaurea angulata on breast cancer cell lines (MDA-MB-231)
by: Zulkipli, Aina Farhana, et al.
Published: (2011)

Design, synthesis, and biological evaluation of new 6,N2-diaryl-1,3,5-triazine-2,4-diamines as anticancer agents selectively targeting triple negative breast cancer cells
by: Ahmad Junaid,, et al.
Published: (2020)

Preliminary study on the effects of winter melon (benincasa hispida) on glycemic profiles: In vivo test on streptozotocin sprague-dawley rats
by: Geduin, Florance
Published: (2014)

An investigation on cytotoxicity effect of putrescine-sulphur analogues in breast cancer (MCF-7), human lung adenocarcinoma (A549) and colorectal cancer (HCT-8) cell lines
by: Halim, Norsuhana, et al.
Published: (2017)

Ficus auriculata (fig) extracts induced cell cycle profile changes and apoptosis through caspase-independent pathway in human LungAdenocarcinoma cell line, A549
by: Jamil, Elyna Fatini, et al.
Published: (2017)

Modelling the cancer growth process by Stochastic Differential Equations with the effect of Chondroitin Sulfate (CS) as anticancer therapeutics
by: Mazlan, Mazma Syahidatul Ayuni, et al.
Published: (2017)

Effects of Palm-tocotrienol Rich Fraction (TRF) on OATP2 protein expression in Bilirubin Transport in adult rats
by: Ismawi, Hidayatul Radziah, et al.
Published: (2011)

Effects of Palm-Tocotrienol Rich Fraction (TRF) on MRP2 Protein Expression in Bilirubin Transport in adult rats
by: Ismawi, Hidayatul Radziah, et al.
Published: (2010)

Kesan in vitro rilmenidine ke atas rembesan insulin
by: Hashim, Rosnani, et al.
Published: (2003)

In vitro vascular activity of crude bungarus candidus and bungarus fasciatus crude venoms
by: Ahmad Rusmili, Muhamad Rusdi, et al.
Published: (2012)

Antifungal activity of three local Malaysian honeys on selected pathogenic fungi of otomycosis ; an in vitro evaluation
by: Hamid, Zubaidah
Published: (2015)

Biological activities of Curcuma purpurascens BI. Rhizome extract using in vitro and in vivo models / Elham Rouhollahi
by: Elham, Rouhollahi
Published: (2016)

Understanding the mechanism of action of denrophthoe pentandra leaves extract as anticancer agent
by: Sul'ain, Mohd Dasuki
Published: (2016)

Antifungal effect of kaffir lime leaf extract on selected fungal species of pathologenic otomycosis in in-vitro culture medium
by: Soffian, Mohd Syafwan Mohd
Published: (2017)

Neural differentiation of human pluripotent stem cells for nontherapeutic applications: Toxicology, pharmacology, and in vitro disease modelling [Review article].
by: Yap, May Shin *, et al.
Published: (2015)

Antifungal effect of piper betle (sireh) leaf extract on selected fungal species of pathogenic otomycosis in in-vitro culture medium
by: Abdullah, Ardhi
Published: (2018)

In-vitro neurotoxicity of two Malaysian krait species (Bungarus candidus and Bungarus fasciatus) venoms: neutralization by monovalent and polyvalent antivenoms from Thailand
by: Asmad Rusmili, Muhamad Rusdi, et al.
Published: (2014)

Tea polyphenols extracted from fresh young tea leaves exhibits antibacterial activity against some bacterial species: An in vitro study
by: Sikder, Md. Belal Hossain, et al.
Published: (2020)

In vitro antimicrobial effect of Gentamicin-N.sativa fusion emulsion against biofilm producing strain S.aureus, P.aeruginosa and S.epidermidis
by: Yaacob, Khairul Ikhwan, et al.
Published: (2014)

Identification of chemical constituents in different propolis extracts and their in vitro antimicrobial activities against propionibacterium acnes and staphylococcus epidermidis : towards the development of a new formulation
by: T. Ismail @ T Manah, Tuan Nadrah Naim
Published: (2015)

Changes in the markers of atherosclerosis following administration of Belimbing dayak (Baccaurea angulata) fruit juice in experimental rabbits fed with cholesterol diet
by: Mikail, Maryam Abimbola, et al.
Published: (2013)

Anticancer effects of eurycoma longifolia, Nigella sativa and hibiscus sabdariffa on ovarian cancer cells
by: Abdullah, 'Afif Raihan, et al.
Published: (2016)

Evaluation of antioxidant, total phenol and flavonoid content and antimicrobial activities of artocarpus altilis (breadfruit) of underutilized tropical fruit extracts
by: Jalal, Tara Kamal, et al.
Published: (2015)

Genetic diversity and natural selection of the rhoptry-associated protein 1 (RAP-1) of recent Plasmodium knowlesi clinical isolates from Malaysia / Mira Syahfriena Amir Rawa
by: Mira Syahfriena , Amir Rawa
Published: (2016)

Dose-and time dependent effects of oil-palm (Elaeis guineensis) leaf extract in streptozocin-induced oxidative stress and renal damage in diabetic rats / Varatharajan Rajavel
by: Vatharajan, Rajavel
Published: (2016)

In ViVo anti-malarial activity of some Malaysian traditional plants: Community's awareness and ethnobotanical survey / Abdulelah Hussien Ahmed Al-Adhroey
by: Abdulelah Hussien, Ahmed Al-Adhroey
Published: (2011)

Formulation and stability testing of gentamicin-Nigella sativa emulsions for osteo-healing application
by: Yusof, Fathin Athirah, et al.
Published: (2014)

Compatibility characterization of Gentamicin-Nigella sativa fusion as a future greener pharmaceutical intended for ortheopaedic infection
by: Harun Ismail, Ahmad Fahmi, et al.
Published: (2014)

Effect of royal jelly on male infertility
by: E. Al-Sanafi, Ali, et al.
Published: (2007)

Toxicological profiles of Carbamazepine, Gabapentin and their combination at high therapeutic doses in rat
by: Abdullah, Sinan Mohammed, et al.
Published: (2014)

Histopathological changes of the cardiac muscle and the adrenal gland in long term diabetic rat
by: Abdullah, Sinan Mohammed, et al.
Published: (2014)