Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet
Supercritical fluid extraction (SFE) using carbon dioxide (CO2) and liquid CO2 using Soxhlet (CO2-Soxhlet) extraction were employed to extract three (3) antidiabetic compounds viz. stigmasterol, quercetin, and avicularin from Mimosa pudica. Various extraction parameters were studied. Extracts were a...
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| Language: | English English English |
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http://www.tandfonline.com/loi/lsst20
2018
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| Online Access: | http://irep.iium.edu.my/60532/ http://irep.iium.edu.my/60532/1/SST-Tunna-Zaidul-2017.pdf http://irep.iium.edu.my/60532/7/60532_Enrichment%2C%20in%20vitro%2C%20and%20quantification_scopus.pdf http://irep.iium.edu.my/60532/13/60532_Enrichment%2C%20in%20vitro%2C%20and%20quantification%20_WoS.pdf |
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| author | Tunna, Tasnuva Sarwar Sarker, Md. Zaidul Islam Ghafoor, Kashif Ferdosh, Sahena Md. Jaffri, Juliana AL-Juhaımı, Fahad Y.I. Ali, Md Eaqub Akanda, Md Jahurul Haque Awal, Md Shihabul Ahmed, Qamar Uddin Selamat, Jinap |
| author_facet | Tunna, Tasnuva Sarwar Sarker, Md. Zaidul Islam Ghafoor, Kashif Ferdosh, Sahena Md. Jaffri, Juliana AL-Juhaımı, Fahad Y.I. Ali, Md Eaqub Akanda, Md Jahurul Haque Awal, Md Shihabul Ahmed, Qamar Uddin Selamat, Jinap |
| author_sort | Tunna, Tasnuva Sarwar |
| building | IIUM Repository |
| collection | Online Access |
| description | Supercritical fluid extraction (SFE) using carbon dioxide (CO2) and liquid CO2 using Soxhlet (CO2-Soxhlet) extraction were employed to extract three (3) antidiabetic compounds viz. stigmasterol, quercetin, and avicularin from Mimosa pudica. Various extraction parameters were studied. Extracts were analyzed pharmacologically, qualitatively and quantitatively to ascertain enrichment levels. All three antidiabetic compounds were effectively enriched under optimized conditions of temperature 60°C, pressure 40 MPa, co-solvent ratio 30%, and CO2 flow rate of 5 ml min−1. SFE was found to be the better method for enrichment of the antidiabetic compounds than the CO2-Soxhlet method. Extraction conditions were seen to affect the enrichment of desired compounds. |
| first_indexed | 2025-11-14T16:54:15Z |
| format | Article |
| id | iium-60532 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English English English |
| last_indexed | 2025-11-14T16:54:15Z |
| publishDate | 2018 |
| publisher | http://www.tandfonline.com/loi/lsst20 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-605322022-12-09T02:33:06Z http://irep.iium.edu.my/60532/ Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet Tunna, Tasnuva Sarwar Sarker, Md. Zaidul Islam Ghafoor, Kashif Ferdosh, Sahena Md. Jaffri, Juliana AL-Juhaımı, Fahad Y.I. Ali, Md Eaqub Akanda, Md Jahurul Haque Awal, Md Shihabul Ahmed, Qamar Uddin Selamat, Jinap RS192 Materia Medica-Pharmaceutical Technology Supercritical fluid extraction (SFE) using carbon dioxide (CO2) and liquid CO2 using Soxhlet (CO2-Soxhlet) extraction were employed to extract three (3) antidiabetic compounds viz. stigmasterol, quercetin, and avicularin from Mimosa pudica. Various extraction parameters were studied. Extracts were analyzed pharmacologically, qualitatively and quantitatively to ascertain enrichment levels. All three antidiabetic compounds were effectively enriched under optimized conditions of temperature 60°C, pressure 40 MPa, co-solvent ratio 30%, and CO2 flow rate of 5 ml min−1. SFE was found to be the better method for enrichment of the antidiabetic compounds than the CO2-Soxhlet method. Extraction conditions were seen to affect the enrichment of desired compounds. http://www.tandfonline.com/loi/lsst20 2018-01-22 Article PeerReviewed application/pdf en http://irep.iium.edu.my/60532/1/SST-Tunna-Zaidul-2017.pdf application/pdf en http://irep.iium.edu.my/60532/7/60532_Enrichment%2C%20in%20vitro%2C%20and%20quantification_scopus.pdf application/pdf en http://irep.iium.edu.my/60532/13/60532_Enrichment%2C%20in%20vitro%2C%20and%20quantification%20_WoS.pdf Tunna, Tasnuva Sarwar and Sarker, Md. Zaidul Islam and Ghafoor, Kashif and Ferdosh, Sahena and Md. Jaffri, Juliana and AL-Juhaımı, Fahad Y.I. and Ali, Md Eaqub and Akanda, Md Jahurul Haque and Awal, Md Shihabul and Ahmed, Qamar Uddin and Selamat, Jinap (2018) Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet. Separation Science and Technology, 53 (2). pp. 243-260. ISSN 0149-6395 E-ISSN 1520-5754 http://www.tandfonline.com/loi/lsst20 10.1080/01496395.2017.1384015 |
| spellingShingle | RS192 Materia Medica-Pharmaceutical Technology Tunna, Tasnuva Sarwar Sarker, Md. Zaidul Islam Ghafoor, Kashif Ferdosh, Sahena Md. Jaffri, Juliana AL-Juhaımı, Fahad Y.I. Ali, Md Eaqub Akanda, Md Jahurul Haque Awal, Md Shihabul Ahmed, Qamar Uddin Selamat, Jinap Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet |
| title | Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet |
| title_full | Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet |
| title_fullStr | Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet |
| title_full_unstemmed | Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet |
| title_short | Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet |
| title_sort | enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed mimosa pudica using supercritical co2 and co2-soxhlet |
| topic | RS192 Materia Medica-Pharmaceutical Technology |
| url | http://irep.iium.edu.my/60532/ http://irep.iium.edu.my/60532/ http://irep.iium.edu.my/60532/ http://irep.iium.edu.my/60532/1/SST-Tunna-Zaidul-2017.pdf http://irep.iium.edu.my/60532/7/60532_Enrichment%2C%20in%20vitro%2C%20and%20quantification_scopus.pdf http://irep.iium.edu.my/60532/13/60532_Enrichment%2C%20in%20vitro%2C%20and%20quantification%20_WoS.pdf |