Thymoquinone inhibits growth of human medulloblastoma cells by inducing oxidative stress and caspase-dependent apoptosis while suppressing NF-jB signaling and IL-8 expression

Thymoquinone inhibits growth of human medulloblastoma cells by inducing oxidative stress and caspase-dependent apoptosis while suppressing NF-jB signaling and IL-8 expression

Medulloblastoma (MB) is the most common malignant brain tumor of childhood. The transcription factor NF-κB is overexpressed in human MB and is a critical factor for MB tumor growth. NF-κB is known to regulate the expression of interleukin-8 (IL-8), the chemokine that enhances cancer cell growth and...

Full description

Bibliographic Details
Main Authors: Ashour, Abdelkader Elbadawy Abbas, Ahmed, Atallah F., Kumar, Ashok, Zoheir, Khairy M. A., Aboul-Soud, Mourad A., Ahmad, Sheikh F., Attia, Sabry M., Abd-Allah, Adel R. A., Cheryan, Vino T., Rishi, Arun K.
Format: Article
Language:English
English
Published: Springer US 2016
Subjects:
RM Therapeutics. Pharmacology
Online Access:http://irep.iium.edu.my/59658/
http://irep.iium.edu.my/59658/1/Thymoquinone%20inhibits%20growth%20of%20human%20medulloblastoma%20cells%20by%20inducing%20oxidative%20stress%20and%20caspase-dependent%20apoptosis%20while%20suppressing%20NF-%CE%BAB%20signaling%20and%20IL-8%20expression.pdf
http://irep.iium.edu.my/59658/7/59658_Thymoquinone%20inhibits%20growth%20of%20human_SCOPUS.pdf

Similar Items

Similar Items