A randomized placebo controlled trial of the effect of preoperative statin use on matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in areas of low and peak wall stress in patients undergoing elective open repair of abdominal aortic aneurysm

QR Code

A randomized placebo controlled trial of the effect of preoperative statin use on matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in areas of low and peak wall stress in patients undergoing elective open repair of abdominal aortic aneurysm

BACKGROUND: A double-blind, randomized controlled trial was carried out to study the effects of statins on matrix metalloproteinases (MMPs) and tissue inhibitors of matrix metalloproteinases (TIMPs) in areas of peak and low abdominal aortic aneurysm (AAA) wall stress. METHODS: A total of 40 patie...

Full description

Bibliographic Details
Main Authors:	Abdul Rahman, Mohd Norhisham Azmi, Khan, Junaidalam, Mazari, Fayyaz Ali Khan, Mockford, Katherine, McCollum, Peter Thomas, Chetter, Ian Clifford
Format:	Article
Language:	English
Published:	Elsevier 2011
Subjects:	RD Surgery
Online Access:	http://irep.iium.edu.my/59244/ http://irep.iium.edu.my/59244/1/A%20randomised%20placebo%20controlled%20trial%20of%20the%20effect%20of%20preoperative%20statin.pdf

Similar Items

Intraluminal Thrombus has a selective Influence on Matrix Metalloproteinases and Their inhibitors (tissue inhibitors of Matrix Metalloproteinases) in the wall of Abdominal Aortic Aneurysms
by: Khan, J. A., et al.
Published: (2012)

Concentration and activity of matrix metalloproteinases and tissue inhibitors of matalloproteinases in the wall of abdominal aortic aneurysm at different wall stress
by: Abdul Rahman, Mohd Norhisham Azmi, et al.
Published: (2008)

Patients' perspective of functional outcome after elective abdominal aortic aneurysm repair: A questionnaire survey
by: Khan, Junaidalam, et al.
Published: (2011)

Matrix metalloproteinases in cancer biology: a review
by: Nabeel, Ibrahim Wisam, et al.
Published: (2019)

Expression of matrix metalloproteinases (mmp-2) in prognostication of meningioma
by: Sharifuddin, Maryam Ahmad
Published: (2020)

Does peak wall stress correlate better with abdominal aortic aneurysm expansion than aortic diameter?
by: Abdul Rahman, Mohd Norhisham Azmi, et al.
Published: (2007)

Pigment epithelium-derived factor as a natural matrix metalloproteinase inhibitor: a comparison with classical matrix metalloproteinase inhibitors used for cancer treatment
by: Alcantara, M., et al.
Published: (2014)

Influencing the degradation rate of recombinant spider silk in the presence of matrix metalloproteinases
by: Coekin, Thomas
Published: (2021)

Association of matrix metalloproteinase-1, 9, 12 and tissue inhibitor of metalloproteinase-1 gene polymorphisms in malay male essential hypertensive subject
by: Tabatabaee, Farizeh Aalam Ghomi
Published: (2015)

Mechanisms of irregular bleeding with hormone therapy: the role of matrix metalloproteinases and their tissue inhibitors
by: Hickey, M., et al.
Published: (2006)

Identifying matrix metalloproteinase-12 substrates as therapeutic targets in chronic obstructive pulmonary disease
by: Mallia-Milanes, Brendan
Published: (2015)

Evaluation of matrix metalloproteinases(MMP-8, -9) in pregnant women attending Hospital USM
by: Rehman, Sarmed Saif-Ur
Published: (2020)

Matrix metalloproteinase-1 mediated extra-cellular matrix remodelling contributes to airway smooth muscle growth and asthma severity
by: Naveed, Shams-un-nisa
Published: (2018)

Expression of matrix metalloproteinase-13 in human skin melanoma cancer treated by Baccaurea angulata in vitro
by: Adam, Magdi, et al.
Published: (2015)

Expression of matrix metalloproteinase-13 in human skin melanoma cancer treated by baccaurea angulata in vitro
by: Abdull Rasad, Mohammad Syaiful Bahari
Published: (2013)

Matrix metalloproteinase activation by free neutrophil elastase contributes to bronchiectasis progression in early cystic fibrosis
by: Garratt, L.W., et al.
Published: (2015)

Serum matrix metalloproteinase-3 predicts radiographic joint damage and functional disability in rheumatoid arthritis
by: Sakthiswary Rajalingham,, et al.
Published: (2016)

Low methylation of matrix metalloproteinase 1 (MMP1) is associated with preterm labour in Malaysian mothers
by: Nurul Hayati Mohamad Zainal,, et al.
Published: (2022)

Elevated serum matrix metalloproteinase 9 concentration predicts the presence of colorectal neoplasia in symptomatic patients
by: Belobrajdic, D., et al.
Published: (2008)

Low methylation of matrix metalloproteinase 1 (MMP1) is associated with preterm labour in Malaysian mothers
by: Mohamad Zainal, Nurul Hayati, et al.
Published: (2022)

A randomised double-blind placebo-controlled trial of the impact of high-dose statins on the ischaemia-reperfusion injury in elective AAA repair
by: Abdul Rahman, Mohd Norhisham Azmi, et al.
Published: (2009)

Extra-cellular matrix proteins induce matrix metalloproteinase-1 (MMP-1) activity and increase airway smooth muscle contraction in asthma
by: Rogers, Natasha K., et al.
Published: (2014)

Characterization of Matrix Metalloproteinases (MMPs) and CTCF protein expressions in several human cancer cell lines in vitro
by: Mat Alewi, Nur Aizura, et al.
Published: (2013)

Matrix Metalloproteinase -9 and Tissue Inhibitors of Metalloproteinasr-1 and -2 as Potential Novel Biomakers in Gestational Hypertension
by: Ab Hamid, Jabrullah
Published: (2010)

Bio-responsive hydrogels for an in vitro brain cancer cell model: self-controlled inhibition of matrix metalloproteinase activity
by: Russo, Emanuele
Published: (2020)

Reduction in tumour cell invasion by pigment epithelium-derived factor is mediated by membrane type-1 matrix metalloproteinase downregulation
by: Filiz, G., et al.
Published: (2012)

Enzymic Milk Clotting Activities of Metalloproteinase Kistomin
by: Jaya Vejayan, Palliah, et al.
Published: (2020)

Expression of collagenases matrix metalloproteinases and YB-1 oncogenic factor in malignant melanoma cancer cells and its regulation by stromal fibroblasts
by: Ibrahim, Wisam Nabeel, et al.
Published: (2017)

Anti–elastase, anti–tyrosinase and matrix metalloproteinase–1 inhibitory activity of earthworm extracts as potential new anti–aging agent
by: Azmi, Nurhazirah, et al.
Published: (2014)

Curcumin reduces prostaglandin E2, matrix metalloproteinase-3 and proteoglycan release in the secretome of interleukin 1β-treated articular cartilage
by: Clutterbuck, Abigail L., et al.
Published: (2013)

Carprofen inhibits the release of matrix metalloproteinases 1, 3, and 13 in the secretome of an explant model of articular cartilage stimulated with interleukin 1β
by: Williams, Adam, et al.
Published: (2013)

Functional characterization of selective exosite-binding inhibitors of matrix metalloproteinase-13 (MMP-13) - Experimental validation in human breast and colon cancer
by: Kothapalli, R., et al.
Published: (2016)

Finite element modelling of abdominal aortic aneurysm
by: Mohd Izzat, Samsudin
Published: (2010)

In vivo ctcf and yb-1 interaction with ap-1 site of matrix metalloproteinase 13 gene promoter in human malignant melanoma cell line
by: Ibrahim, Wisam Nabeel, et al.
Published: (2014)

Cost utility analysis of a randomised control trial of percutaneoustransluminal angioplasty (PTA), supervised exercise programme (SEP) and combined treatment (PTA+SEP) for patients with intermittent claudication (IC) due to femoropopliteal disease
by: Mazari, Fayyaz Ali Khan, et al.
Published: (2010)

Applications of computational fluid dynamics in abdominal aortic aneurysms
by: Sun, Zhonghua
Published: (2013)

Novel Association between Plasma Matrix Metalloproteinase-9 and Risk of Incident Atrial Fibrillation in a Case-Cohort Study: The Atherosclerosis Risk in Communities Study
by: Huxley, Rachel, et al.
Published: (2013)

Comprehending the pharmacological mechanism of marine phenolic acids in bladder cancer therapy against matrix metalloproteinase 9 protein by integrated network pharmacology and in-silico approaches
by: Roney, Miah, et al.
Published: (2024)

Statins and ischaemia reperfusion injury: a molecular biological review
by: Abdul Rahman, Mohd Norhisham Azmi, et al.
Published: (2010)

Attenuation of urokinase activity during experimental ischaemia protects the cerebral barrier from damage through regulation of matrix metalloproteinase-2 and NAD(P)H oxidase
by: Rakkar, Kamini, et al.
Published: (2014)