Abdominal obesity and high-sensitivity C-reactive protein level among Malay obese adults in Kuantan, Malaysia
Introduction: Abdominal obesity and inflammation are two independent risk factors for cardiovascular disease. However, the inter-relationship between these two factors among Malay population is fragmented. The purpose of this study is to determine the association between waist circumference as a mea...
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| Format: | Article |
| Language: | English English English |
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Kulliyyah (Faculty) of Medicine, International Islamic University Malaysia
2018
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| Online Access: | http://irep.iium.edu.my/58135/ http://irep.iium.edu.my/58135/19/58135%20Abdominal%20Obesity%20and%20High-sensitivity%20C-reactive.pdf http://irep.iium.edu.my/58135/13/58135_Abdominal%20Obesity%20and%20High-sensitivity%20C-reactive%20Protein%20Level_SCOPUS.pdf http://irep.iium.edu.my/58135/25/58135_Abdominal%20Obesity%20and%20High-sensitivity%20C-reactive%20Protein%20Level%20among%20Malay%20Obese%20Adults%20in%20Kuantan%2C%20Malaysia_WOS.pdf |
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| author | Shahadan, Siti Zuhaidah Daud, Azlina Md. Isa, Muhammad Lokman Mohd Rasani, Ali Aminuddin Ibrahim, Muhammad Draman, Samsul |
| author_facet | Shahadan, Siti Zuhaidah Daud, Azlina Md. Isa, Muhammad Lokman Mohd Rasani, Ali Aminuddin Ibrahim, Muhammad Draman, Samsul |
| author_sort | Shahadan, Siti Zuhaidah |
| building | IIUM Repository |
| collection | Online Access |
| description | Introduction: Abdominal obesity and inflammation are two independent risk factors for cardiovascular disease. However, the inter-relationship between these two factors among Malay population is fragmented. The purpose of this study is to determine the association between waist circumference as a measure of abdominal obesity and high-sensitivity C-reactive protein as an indicator of inflammation status among Malay obese adults in Kuantan, Pahang.
Materials and Methods: Ninety-three apparently healthy obese adults (BMI between 27.5 and 39.9 kg/m2) aged between 20 to 62 years old were recruited in this study (68% men and 32% women). Circumference tape was used to measure the waist circumference and fasting venous blood was obtained to determine the high-sensitivity C-reactive protein level.
Results: On average, the waist circumference of obese men and women was 103 cm (SD = 8.7) and 94 cm (SD = 7.0), respectively. The median (IQR) of the hs-CRP level of the study participant was 3.80 mg/L (1.5, 10.1). The Kendall’s Tau correlation reveals that there is a significant positive linear correlation between waist circumference and hs-CRP level in obese men (r (30) = 0.355, p = 0.006) and women (r (63) = 0.177, p = 0.043).
Conclusion: There is a significant inter-relationship between waist circumference and hs-CRP level among apparently healthy obese adults in Kuantan, Pahang. This study suggests that assessment of hs-CRP level is beneficial to predict the risk for future cardiovascular disease event and facilitate the management of obesity in this population. A prospective clinical study is recommended to confirm the findings. |
| first_indexed | 2025-11-14T16:47:05Z |
| format | Article |
| id | iium-58135 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English English English |
| last_indexed | 2025-11-14T16:47:05Z |
| publishDate | 2018 |
| publisher | Kulliyyah (Faculty) of Medicine, International Islamic University Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-581352019-01-24T01:42:07Z http://irep.iium.edu.my/58135/ Abdominal obesity and high-sensitivity C-reactive protein level among Malay obese adults in Kuantan, Malaysia Shahadan, Siti Zuhaidah Daud, Azlina Md. Isa, Muhammad Lokman Mohd Rasani, Ali Aminuddin Ibrahim, Muhammad Draman, Samsul RT Nursing Introduction: Abdominal obesity and inflammation are two independent risk factors for cardiovascular disease. However, the inter-relationship between these two factors among Malay population is fragmented. The purpose of this study is to determine the association between waist circumference as a measure of abdominal obesity and high-sensitivity C-reactive protein as an indicator of inflammation status among Malay obese adults in Kuantan, Pahang. Materials and Methods: Ninety-three apparently healthy obese adults (BMI between 27.5 and 39.9 kg/m2) aged between 20 to 62 years old were recruited in this study (68% men and 32% women). Circumference tape was used to measure the waist circumference and fasting venous blood was obtained to determine the high-sensitivity C-reactive protein level. Results: On average, the waist circumference of obese men and women was 103 cm (SD = 8.7) and 94 cm (SD = 7.0), respectively. The median (IQR) of the hs-CRP level of the study participant was 3.80 mg/L (1.5, 10.1). The Kendall’s Tau correlation reveals that there is a significant positive linear correlation between waist circumference and hs-CRP level in obese men (r (30) = 0.355, p = 0.006) and women (r (63) = 0.177, p = 0.043). Conclusion: There is a significant inter-relationship between waist circumference and hs-CRP level among apparently healthy obese adults in Kuantan, Pahang. This study suggests that assessment of hs-CRP level is beneficial to predict the risk for future cardiovascular disease event and facilitate the management of obesity in this population. A prospective clinical study is recommended to confirm the findings. Kulliyyah (Faculty) of Medicine, International Islamic University Malaysia 2018-04 Article PeerReviewed application/pdf en http://irep.iium.edu.my/58135/19/58135%20Abdominal%20Obesity%20and%20High-sensitivity%20C-reactive.pdf application/pdf en http://irep.iium.edu.my/58135/13/58135_Abdominal%20Obesity%20and%20High-sensitivity%20C-reactive%20Protein%20Level_SCOPUS.pdf application/pdf en http://irep.iium.edu.my/58135/25/58135_Abdominal%20Obesity%20and%20High-sensitivity%20C-reactive%20Protein%20Level%20among%20Malay%20Obese%20Adults%20in%20Kuantan%2C%20Malaysia_WOS.pdf Shahadan, Siti Zuhaidah and Daud, Azlina and Md. Isa, Muhammad Lokman and Mohd Rasani, Ali Aminuddin and Ibrahim, Muhammad and Draman, Samsul (2018) Abdominal obesity and high-sensitivity C-reactive protein level among Malay obese adults in Kuantan, Malaysia. International Medical Journal Malaysia, 17 (1). pp. 79-86. E-ISSN 1823-4631 http://iiumedic.net/imjm/v1/download/volume_17_no_1/Vol17-No1-p079086.pdf |
| spellingShingle | RT Nursing Shahadan, Siti Zuhaidah Daud, Azlina Md. Isa, Muhammad Lokman Mohd Rasani, Ali Aminuddin Ibrahim, Muhammad Draman, Samsul Abdominal obesity and high-sensitivity C-reactive protein level among Malay obese adults in Kuantan, Malaysia |
| title | Abdominal obesity and high-sensitivity C-reactive protein level among Malay obese adults in Kuantan, Malaysia |
| title_full | Abdominal obesity and high-sensitivity C-reactive protein level among Malay obese adults in Kuantan, Malaysia |
| title_fullStr | Abdominal obesity and high-sensitivity C-reactive protein level among Malay obese adults in Kuantan, Malaysia |
| title_full_unstemmed | Abdominal obesity and high-sensitivity C-reactive protein level among Malay obese adults in Kuantan, Malaysia |
| title_short | Abdominal obesity and high-sensitivity C-reactive protein level among Malay obese adults in Kuantan, Malaysia |
| title_sort | abdominal obesity and high-sensitivity c-reactive protein level among malay obese adults in kuantan, malaysia |
| topic | RT Nursing |
| url | http://irep.iium.edu.my/58135/ http://irep.iium.edu.my/58135/ http://irep.iium.edu.my/58135/19/58135%20Abdominal%20Obesity%20and%20High-sensitivity%20C-reactive.pdf http://irep.iium.edu.my/58135/13/58135_Abdominal%20Obesity%20and%20High-sensitivity%20C-reactive%20Protein%20Level_SCOPUS.pdf http://irep.iium.edu.my/58135/25/58135_Abdominal%20Obesity%20and%20High-sensitivity%20C-reactive%20Protein%20Level%20among%20Malay%20Obese%20Adults%20in%20Kuantan%2C%20Malaysia_WOS.pdf |