Efficacy and safety of SPRINT and STAR protocol on Malaysian critically-ill patients

Abstract—Intensive care unit patients may have a better glycaemic management with the right control protocol. Results of virtual trial performance on Malaysian critically-ill patients adopting a model-derived and model-based control protocol known as SPRINT and STAR are presented in this paper. Thes...

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Main Authors: Ahamad, Nurhamim, Abdul Razak, Normy Norfiza, Jamaludin, Ummu Kulthum, Suhaimi, Fatanah M., Pretty, Christopher G., Chase, Geoffrey, Md Ralib, Azrina, Mat Nor, Mohd Basri
Format: Proceeding Paper
Language:English
English
English
Published: IEEE 2017
Subjects:
Online Access:http://irep.iium.edu.my/56098/
http://irep.iium.edu.my/56098/7/56098%20Efficacy%20and%20safety%20of%20SPRINT%20and%20STAR%20protocol.pdf
http://irep.iium.edu.my/56098/8/56098%20Efficacy%20and%20safety%20of%20SPRINT%20and%20STAR%20SCOPUS.pdf
http://irep.iium.edu.my/56098/19/56098_Efficacy%20and%20safety%20of%20SPRINT%20and%20STAR_WOS.pdf
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author Ahamad, Nurhamim
Abdul Razak, Normy Norfiza
Jamaludin, Ummu Kulthum
Suhaimi, Fatanah M.
Pretty, Christopher G.
Chase, Geoffrey
Md Ralib, Azrina
Mat Nor, Mohd Basri
author_facet Ahamad, Nurhamim
Abdul Razak, Normy Norfiza
Jamaludin, Ummu Kulthum
Suhaimi, Fatanah M.
Pretty, Christopher G.
Chase, Geoffrey
Md Ralib, Azrina
Mat Nor, Mohd Basri
author_sort Ahamad, Nurhamim
building IIUM Repository
collection Online Access
description Abstract—Intensive care unit patients may have a better glycaemic management with the right control protocol. Results of virtual trial performance on Malaysian critically-ill patients adopting a model-derived and model-based control protocol known as SPRINT and STAR are presented in this paper. These ICU patients have been treated by intensive sliding-scale insulin infusion. The effectiveness and safety of glycaemic control are then analysed. Results showed that patient safety improved by 83% with SPRINT and STAR protocol as the number of hypoglycaemic patients significantly reduced (BG<2.2 mmol/L). Percentage of time within desired bands and median BG improves in both SPRINT and STAR. However the improvements are associated with higher number of BG measurements (workload).
first_indexed 2025-11-14T16:41:08Z
format Proceeding Paper
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institution International Islamic University Malaysia
institution_category Local University
language English
English
English
last_indexed 2025-11-14T16:41:08Z
publishDate 2017
publisher IEEE
recordtype eprints
repository_type Digital Repository
spelling iium-560982020-07-15T02:46:28Z http://irep.iium.edu.my/56098/ Efficacy and safety of SPRINT and STAR protocol on Malaysian critically-ill patients Ahamad, Nurhamim Abdul Razak, Normy Norfiza Jamaludin, Ummu Kulthum Suhaimi, Fatanah M. Pretty, Christopher G. Chase, Geoffrey Md Ralib, Azrina Mat Nor, Mohd Basri R Medicine (General) Abstract—Intensive care unit patients may have a better glycaemic management with the right control protocol. Results of virtual trial performance on Malaysian critically-ill patients adopting a model-derived and model-based control protocol known as SPRINT and STAR are presented in this paper. These ICU patients have been treated by intensive sliding-scale insulin infusion. The effectiveness and safety of glycaemic control are then analysed. Results showed that patient safety improved by 83% with SPRINT and STAR protocol as the number of hypoglycaemic patients significantly reduced (BG<2.2 mmol/L). Percentage of time within desired bands and median BG improves in both SPRINT and STAR. However the improvements are associated with higher number of BG measurements (workload). IEEE 2017-02-06 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/56098/7/56098%20Efficacy%20and%20safety%20of%20SPRINT%20and%20STAR%20protocol.pdf application/pdf en http://irep.iium.edu.my/56098/8/56098%20Efficacy%20and%20safety%20of%20SPRINT%20and%20STAR%20SCOPUS.pdf application/pdf en http://irep.iium.edu.my/56098/19/56098_Efficacy%20and%20safety%20of%20SPRINT%20and%20STAR_WOS.pdf Ahamad, Nurhamim and Abdul Razak, Normy Norfiza and Jamaludin, Ummu Kulthum and Suhaimi, Fatanah M. and Pretty, Christopher G. and Chase, Geoffrey and Md Ralib, Azrina and Mat Nor, Mohd Basri (2017) Efficacy and safety of SPRINT and STAR protocol on Malaysian critically-ill patients. In: 2016 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES), 4th-8th December 2016, Kuala Lumpur. http://ieeexplore.ieee.org/document/7843476/ 10.1109/IECBES.2016.7843476
spellingShingle R Medicine (General)
Ahamad, Nurhamim
Abdul Razak, Normy Norfiza
Jamaludin, Ummu Kulthum
Suhaimi, Fatanah M.
Pretty, Christopher G.
Chase, Geoffrey
Md Ralib, Azrina
Mat Nor, Mohd Basri
Efficacy and safety of SPRINT and STAR protocol on Malaysian critically-ill patients
title Efficacy and safety of SPRINT and STAR protocol on Malaysian critically-ill patients
title_full Efficacy and safety of SPRINT and STAR protocol on Malaysian critically-ill patients
title_fullStr Efficacy and safety of SPRINT and STAR protocol on Malaysian critically-ill patients
title_full_unstemmed Efficacy and safety of SPRINT and STAR protocol on Malaysian critically-ill patients
title_short Efficacy and safety of SPRINT and STAR protocol on Malaysian critically-ill patients
title_sort efficacy and safety of sprint and star protocol on malaysian critically-ill patients
topic R Medicine (General)
url http://irep.iium.edu.my/56098/
http://irep.iium.edu.my/56098/
http://irep.iium.edu.my/56098/
http://irep.iium.edu.my/56098/7/56098%20Efficacy%20and%20safety%20of%20SPRINT%20and%20STAR%20protocol.pdf
http://irep.iium.edu.my/56098/8/56098%20Efficacy%20and%20safety%20of%20SPRINT%20and%20STAR%20SCOPUS.pdf
http://irep.iium.edu.my/56098/19/56098_Efficacy%20and%20safety%20of%20SPRINT%20and%20STAR_WOS.pdf