Enriched extracts of anti-diabetic compounds from neglected weed M. Pudica using supercritical and subcritical carbon dioxide extractions and the corresponding in vitro study for diabetes mellitus
Medicinal plants and various extracts are traditionally used to treat ailments, disease and infections. Traditionally, organic solvents, water and oil were and are still used for the extraction of herbal medicine and often boiling (percolation) and vigorous techniques to separate the bioactive compo...
| Main Authors: | , , , , |
|---|---|
| Format: | Proceeding Paper |
| Language: | English |
| Published: |
2016
|
| Subjects: | |
| Online Access: | http://irep.iium.edu.my/55757/ http://irep.iium.edu.my/55757/2/55757.pdf |
| _version_ | 1848784626645991424 |
|---|---|
| author | Tunna, Tasnuva Sarwar Sarker, Md. Zaidul Islam Ahmed, Qamar Uddin Md. Jaffri, Juliana Ferdoush, Sahena |
| author_facet | Tunna, Tasnuva Sarwar Sarker, Md. Zaidul Islam Ahmed, Qamar Uddin Md. Jaffri, Juliana Ferdoush, Sahena |
| author_sort | Tunna, Tasnuva Sarwar |
| building | IIUM Repository |
| collection | Online Access |
| description | Medicinal plants and various extracts are traditionally used to treat ailments, disease and infections. Traditionally, organic solvents, water and oil were and are still used for the extraction of herbal medicine and often boiling (percolation) and vigorous techniques to separate the bioactive compounds were employed. Along with the advent of green technology and extraction methods, organic solvent-free extract preparation is on the rise. The current study aimed to undergo enrichment of chosen pre-isolated anti-diabetic compounds from M. pudica. The current study was employed using supercritical CO2 extraction (SFE) and subcritical CO2 Soxhlet by studying parameters of temperature, pressure, modifier or co-solvent and flow rate of CO2. It was found that the SFE and CO2-Soxhlet can be utilized to collect extract enriched with anti-diabetic compounds, which are stigmasterol, quercetin and avicularin from M. pudica in a clean and healthier method for future anti-diabetic implications. |
| first_indexed | 2025-11-14T16:40:14Z |
| format | Proceeding Paper |
| id | iium-55757 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T16:40:14Z |
| publishDate | 2016 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-557572017-03-07T03:23:08Z http://irep.iium.edu.my/55757/ Enriched extracts of anti-diabetic compounds from neglected weed M. Pudica using supercritical and subcritical carbon dioxide extractions and the corresponding in vitro study for diabetes mellitus Tunna, Tasnuva Sarwar Sarker, Md. Zaidul Islam Ahmed, Qamar Uddin Md. Jaffri, Juliana Ferdoush, Sahena Q Science (General) Medicinal plants and various extracts are traditionally used to treat ailments, disease and infections. Traditionally, organic solvents, water and oil were and are still used for the extraction of herbal medicine and often boiling (percolation) and vigorous techniques to separate the bioactive compounds were employed. Along with the advent of green technology and extraction methods, organic solvent-free extract preparation is on the rise. The current study aimed to undergo enrichment of chosen pre-isolated anti-diabetic compounds from M. pudica. The current study was employed using supercritical CO2 extraction (SFE) and subcritical CO2 Soxhlet by studying parameters of temperature, pressure, modifier or co-solvent and flow rate of CO2. It was found that the SFE and CO2-Soxhlet can be utilized to collect extract enriched with anti-diabetic compounds, which are stigmasterol, quercetin and avicularin from M. pudica in a clean and healthier method for future anti-diabetic implications. 2016 Proceeding Paper NonPeerReviewed application/pdf en http://irep.iium.edu.my/55757/2/55757.pdf Tunna, Tasnuva Sarwar and Sarker, Md. Zaidul Islam and Ahmed, Qamar Uddin and Md. Jaffri, Juliana and Ferdoush, Sahena (2016) Enriched extracts of anti-diabetic compounds from neglected weed M. Pudica using supercritical and subcritical carbon dioxide extractions and the corresponding in vitro study for diabetes mellitus. In: 2nd International Conference on Industrial Pharmacy (ICIP 2016), 15th-16th Aug. 2016, Kuantan, Pahang. (Unpublished) |
| spellingShingle | Q Science (General) Tunna, Tasnuva Sarwar Sarker, Md. Zaidul Islam Ahmed, Qamar Uddin Md. Jaffri, Juliana Ferdoush, Sahena Enriched extracts of anti-diabetic compounds from neglected weed M. Pudica using supercritical and subcritical carbon dioxide extractions and the corresponding in vitro study for diabetes mellitus |
| title | Enriched extracts of anti-diabetic compounds from neglected weed M. Pudica using supercritical and subcritical carbon dioxide extractions and the corresponding in vitro study for diabetes mellitus |
| title_full | Enriched extracts of anti-diabetic compounds from neglected weed M. Pudica using supercritical and subcritical carbon dioxide extractions and the corresponding in vitro study for diabetes mellitus |
| title_fullStr | Enriched extracts of anti-diabetic compounds from neglected weed M. Pudica using supercritical and subcritical carbon dioxide extractions and the corresponding in vitro study for diabetes mellitus |
| title_full_unstemmed | Enriched extracts of anti-diabetic compounds from neglected weed M. Pudica using supercritical and subcritical carbon dioxide extractions and the corresponding in vitro study for diabetes mellitus |
| title_short | Enriched extracts of anti-diabetic compounds from neglected weed M. Pudica using supercritical and subcritical carbon dioxide extractions and the corresponding in vitro study for diabetes mellitus |
| title_sort | enriched extracts of anti-diabetic compounds from neglected weed m. pudica using supercritical and subcritical carbon dioxide extractions and the corresponding in vitro study for diabetes mellitus |
| topic | Q Science (General) |
| url | http://irep.iium.edu.my/55757/ http://irep.iium.edu.my/55757/2/55757.pdf |