Plasma cholinesterase assay among Malaysian vector control operators occupationally exposed to insecticides

Increase in insecticide space spraying (fogging) activities in Selangor, Malaysia for management of dengue outbreaks submits vector control operators towards occupational low-level exposure towards hazardous organophosphate and pyrethroid compounds. Hence, this study was aimed to determine insect...

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Main Authors: Rostam, Muhamad Ashraf, Hassan, Zuridah
Format: Article
Language:English
Published: Saudi German Hospitals (SGH) Group 2011
Subjects:
Online Access:http://irep.iium.edu.my/55397/
http://irep.iium.edu.my/55397/12/55397.pdf
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author Rostam, Muhamad Ashraf
Hassan, Zuridah
author_facet Rostam, Muhamad Ashraf
Hassan, Zuridah
author_sort Rostam, Muhamad Ashraf
building IIUM Repository
collection Online Access
description Increase in insecticide space spraying (fogging) activities in Selangor, Malaysia for management of dengue outbreaks submits vector control operators towards occupational low-level exposure towards hazardous organophosphate and pyrethroid compounds. Hence, this study was aimed to determine insecticide poisoning among these workers occupationally exposed to insecticides. Plasma cholinesterase level was assayed on 106 vector control operators (subject group) and 74 blood donor samples (control group) to identify insecticide poisoning. Information regarding the workers recent exposure, type of insecticides used and compliance to personal protective equipment was obtained through questionnaire. Statistical analysis was then applied to determine differences in cholinesterase mean level between the subject and control group. Comparison of mean cholinesterase level between the subjects (7879.70 ±227.94 IU/L) and control group (7067.86 ±1609.71 IU/L) showed significantly higher (p<0.05) mean cholinesterase level in the subject group. The study indicated absence of inhibition of cholinesterase level among subject group compared to the control group thus reflects free from organophosphate poisoning in the vector control operators. Majority of the vector control operators were Malays. Strict implementation of personal protective equipment use proved to prevent pesticide poisoning among these workers. These mean cholinesterase levels for both different cohorts is therefore recommended to be used as reference and need to be updated from time to time. However, it is better if each individual cholinesterase level is made available as compared to mean population value
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spelling iium-553972017-03-23T03:52:33Z http://irep.iium.edu.my/55397/ Plasma cholinesterase assay among Malaysian vector control operators occupationally exposed to insecticides Rostam, Muhamad Ashraf Hassan, Zuridah QP Physiology R Medicine (General) RA1190 Toxicology Increase in insecticide space spraying (fogging) activities in Selangor, Malaysia for management of dengue outbreaks submits vector control operators towards occupational low-level exposure towards hazardous organophosphate and pyrethroid compounds. Hence, this study was aimed to determine insecticide poisoning among these workers occupationally exposed to insecticides. Plasma cholinesterase level was assayed on 106 vector control operators (subject group) and 74 blood donor samples (control group) to identify insecticide poisoning. Information regarding the workers recent exposure, type of insecticides used and compliance to personal protective equipment was obtained through questionnaire. Statistical analysis was then applied to determine differences in cholinesterase mean level between the subject and control group. Comparison of mean cholinesterase level between the subjects (7879.70 ±227.94 IU/L) and control group (7067.86 ±1609.71 IU/L) showed significantly higher (p<0.05) mean cholinesterase level in the subject group. The study indicated absence of inhibition of cholinesterase level among subject group compared to the control group thus reflects free from organophosphate poisoning in the vector control operators. Majority of the vector control operators were Malays. Strict implementation of personal protective equipment use proved to prevent pesticide poisoning among these workers. These mean cholinesterase levels for both different cohorts is therefore recommended to be used as reference and need to be updated from time to time. However, it is better if each individual cholinesterase level is made available as compared to mean population value Saudi German Hospitals (SGH) Group 2011-06 Article PeerReviewed application/pdf en http://irep.iium.edu.my/55397/12/55397.pdf Rostam, Muhamad Ashraf and Hassan, Zuridah (2011) Plasma cholinesterase assay among Malaysian vector control operators occupationally exposed to insecticides. Saudi German Hospital Medical Journal, 5 (2). pp. 115-127. ISSN 1658-2489
spellingShingle QP Physiology
R Medicine (General)
RA1190 Toxicology
Rostam, Muhamad Ashraf
Hassan, Zuridah
Plasma cholinesterase assay among Malaysian vector control operators occupationally exposed to insecticides
title Plasma cholinesterase assay among Malaysian vector control operators occupationally exposed to insecticides
title_full Plasma cholinesterase assay among Malaysian vector control operators occupationally exposed to insecticides
title_fullStr Plasma cholinesterase assay among Malaysian vector control operators occupationally exposed to insecticides
title_full_unstemmed Plasma cholinesterase assay among Malaysian vector control operators occupationally exposed to insecticides
title_short Plasma cholinesterase assay among Malaysian vector control operators occupationally exposed to insecticides
title_sort plasma cholinesterase assay among malaysian vector control operators occupationally exposed to insecticides
topic QP Physiology
R Medicine (General)
RA1190 Toxicology
url http://irep.iium.edu.my/55397/
http://irep.iium.edu.my/55397/12/55397.pdf