Porous hydroxyapatite for artificial bone applications
Hydroxyapatite (HA) has been used clinically for many years. It has good biocompatibility in bone contact as its chemical composition is similar to that of bone material. Porous HA ceramics have found enormous use in biomedical applications including bone tissue regeneration, cell proliferation, and...
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| Format: | Article |
| Language: | English |
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Elsevier
2007
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| Online Access: | http://irep.iium.edu.my/5477/ http://irep.iium.edu.my/5477/1/STAM_porous_HA-Published.pdf |
| _version_ | 1848776510365761536 |
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| author | Iis, Sopyan Mel, Maizirwan Singh, Ramesh Khalid, Kamarul Ariffin |
| author_facet | Iis, Sopyan Mel, Maizirwan Singh, Ramesh Khalid, Kamarul Ariffin |
| author_sort | Iis, Sopyan |
| building | IIUM Repository |
| collection | Online Access |
| description | Hydroxyapatite (HA) has been used clinically for many years. It has good biocompatibility in bone contact as its chemical composition is similar to that of bone material. Porous HA ceramics have found enormous use in biomedical applications including bone tissue regeneration, cell proliferation, and drug delivery. In bone tissue engineering it has been applied as filling material for bone defects and augmentation, artificial bone graft material, and prosthesis revision surgery. Its high surface area leads to excellent osteoconductivity and resorbability providing fast bone ingrowth. Porous HA can be produced by a number of methods including conversion of natural bones,
ceramic foaming technique, polymeric sponge method, gel casting of foams, starch consolidation, microwave processing, slip casting, and electrophoretic deposition technique. Some of these methods have been combined to fabricate porous HA with improved properties.
These combination methods have yielded some promising results. This paper discusses briefly fundamental aspects of porous HA for artificial bone applications as well as various techniques used to prepare porous HA. Some of our recent results on development ofmporous HA will be presented as well. |
| first_indexed | 2025-11-14T14:31:14Z |
| format | Article |
| id | iium-5477 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T14:31:14Z |
| publishDate | 2007 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-54772015-09-14T04:21:55Z http://irep.iium.edu.my/5477/ Porous hydroxyapatite for artificial bone applications Iis, Sopyan Mel, Maizirwan Singh, Ramesh Khalid, Kamarul Ariffin TP155 Chemical engineering TP248.13 Biotechnology Hydroxyapatite (HA) has been used clinically for many years. It has good biocompatibility in bone contact as its chemical composition is similar to that of bone material. Porous HA ceramics have found enormous use in biomedical applications including bone tissue regeneration, cell proliferation, and drug delivery. In bone tissue engineering it has been applied as filling material for bone defects and augmentation, artificial bone graft material, and prosthesis revision surgery. Its high surface area leads to excellent osteoconductivity and resorbability providing fast bone ingrowth. Porous HA can be produced by a number of methods including conversion of natural bones, ceramic foaming technique, polymeric sponge method, gel casting of foams, starch consolidation, microwave processing, slip casting, and electrophoretic deposition technique. Some of these methods have been combined to fabricate porous HA with improved properties. These combination methods have yielded some promising results. This paper discusses briefly fundamental aspects of porous HA for artificial bone applications as well as various techniques used to prepare porous HA. Some of our recent results on development ofmporous HA will be presented as well. Elsevier 2007 Article PeerReviewed application/pdf en http://irep.iium.edu.my/5477/1/STAM_porous_HA-Published.pdf Iis, Sopyan and Mel, Maizirwan and Singh, Ramesh and Khalid, Kamarul Ariffin (2007) Porous hydroxyapatite for artificial bone applications. Science and Technology of Advanced Materials, 8 (1-2). pp. 116-123. ISSN 1468-6996 http://www.sciencedirect.com 10.1016/j.stam.2006.11.017 |
| spellingShingle | TP155 Chemical engineering TP248.13 Biotechnology Iis, Sopyan Mel, Maizirwan Singh, Ramesh Khalid, Kamarul Ariffin Porous hydroxyapatite for artificial bone applications |
| title | Porous hydroxyapatite for artificial bone applications |
| title_full | Porous hydroxyapatite for artificial bone applications |
| title_fullStr | Porous hydroxyapatite for artificial bone applications |
| title_full_unstemmed | Porous hydroxyapatite for artificial bone applications |
| title_short | Porous hydroxyapatite for artificial bone applications |
| title_sort | porous hydroxyapatite for artificial bone applications |
| topic | TP155 Chemical engineering TP248.13 Biotechnology |
| url | http://irep.iium.edu.my/5477/ http://irep.iium.edu.my/5477/ http://irep.iium.edu.my/5477/ http://irep.iium.edu.my/5477/1/STAM_porous_HA-Published.pdf |