Serum E3 SUMO-protein ligase NSE2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients
Objective: To prove probable relations between serum E3 SUMO-protein ligase NSE2 (NSMCE2) concentration, peroxynitrite related to oxidative stress in nephrolithiasis patients. Methods: A total of 60 patients with nephrolithiasis and 50 healthy volunteers were involved in this study. Colorimetric...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English English |
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Elsevier BV
2016
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| Online Access: | http://irep.iium.edu.my/54726/ http://irep.iium.edu.my/54726/13/54726_Serum%20E3%20SUMO-protein.pdf http://irep.iium.edu.my/54726/14/54726_Serum%20E3%20SUMO-protein_SCOPUS.pdf |
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| author | Mehde, Atheer Awad Yusof, Faridah Mehdi, Wesen Adel Ahmed Raus, Raha Othman Farhan, Layla Zainulabdeen, Jwan Abdulmohsin Zainal Abidin, Zaima Azira Ghazali, Hamid Abd Rahman, Azlina |
| author_facet | Mehde, Atheer Awad Yusof, Faridah Mehdi, Wesen Adel Ahmed Raus, Raha Othman Farhan, Layla Zainulabdeen, Jwan Abdulmohsin Zainal Abidin, Zaima Azira Ghazali, Hamid Abd Rahman, Azlina |
| author_sort | Mehde, Atheer Awad |
| building | IIUM Repository |
| collection | Online Access |
| description | Objective: To prove probable relations between serum E3 SUMO-protein ligase NSE2 (NSMCE2) concentration, peroxynitrite related to oxidative stress in nephrolithiasis
patients.
Methods: A total of 60 patients with nephrolithiasis and 50 healthy volunteers were
involved in this study. Colorimetric method was used to detect blood urea, creatinine, uric
acid, protein, albumin, total antioxidant status, total oxidant status, peroxynitrite, nitric
oxide and oxidative stress index. Glutathione, NSMCE2 and superoxide dismutase were
measured by ELISA.
Results: A significant increase in level of peroxynitrite, total oxidant status, NSMCE2
and oxidative stress index in patients was observed, while total antioxidant status and
glutathione were significantly decreased.
Conclusions: The study concluded that serum NSMCE2 significantly correlated with
peroxynitrite and oxidative stress in patients with nephrolithiasis. |
| first_indexed | 2025-11-14T16:37:35Z |
| format | Article |
| id | iium-54726 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-14T16:37:35Z |
| publishDate | 2016 |
| publisher | Elsevier BV |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-547262017-02-21T07:51:55Z http://irep.iium.edu.my/54726/ Serum E3 SUMO-protein ligase NSE2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients Mehde, Atheer Awad Yusof, Faridah Mehdi, Wesen Adel Ahmed Raus, Raha Othman Farhan, Layla Zainulabdeen, Jwan Abdulmohsin Zainal Abidin, Zaima Azira Ghazali, Hamid Abd Rahman, Azlina R Medicine (General) Objective: To prove probable relations between serum E3 SUMO-protein ligase NSE2 (NSMCE2) concentration, peroxynitrite related to oxidative stress in nephrolithiasis patients. Methods: A total of 60 patients with nephrolithiasis and 50 healthy volunteers were involved in this study. Colorimetric method was used to detect blood urea, creatinine, uric acid, protein, albumin, total antioxidant status, total oxidant status, peroxynitrite, nitric oxide and oxidative stress index. Glutathione, NSMCE2 and superoxide dismutase were measured by ELISA. Results: A significant increase in level of peroxynitrite, total oxidant status, NSMCE2 and oxidative stress index in patients was observed, while total antioxidant status and glutathione were significantly decreased. Conclusions: The study concluded that serum NSMCE2 significantly correlated with peroxynitrite and oxidative stress in patients with nephrolithiasis. Elsevier BV 2016-12-10 Article PeerReviewed application/pdf en http://irep.iium.edu.my/54726/13/54726_Serum%20E3%20SUMO-protein.pdf application/pdf en http://irep.iium.edu.my/54726/14/54726_Serum%20E3%20SUMO-protein_SCOPUS.pdf Mehde, Atheer Awad and Yusof, Faridah and Mehdi, Wesen Adel and Ahmed Raus, Raha and Othman Farhan, Layla and Zainulabdeen, Jwan Abdulmohsin and Zainal Abidin, Zaima Azira and Ghazali, Hamid and Abd Rahman, Azlina (2016) Serum E3 SUMO-protein ligase NSE2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients. Asian Pacific Journal of Tropical Biomedicine, 7 (3). pp. 249-252. ISSN 2221-1691 http://ac.els-cdn.com/S2221169116302192/1-s2.0-S2221169116302192-main.pdf?_tid=f6f2e420-f808-11e6-9647-00000aab0f6c&acdnat=1487662986_f0120fdce9a679cc59600706bf5d349f 10.1016/j.apjtb.2016.12.008 |
| spellingShingle | R Medicine (General) Mehde, Atheer Awad Yusof, Faridah Mehdi, Wesen Adel Ahmed Raus, Raha Othman Farhan, Layla Zainulabdeen, Jwan Abdulmohsin Zainal Abidin, Zaima Azira Ghazali, Hamid Abd Rahman, Azlina Serum E3 SUMO-protein ligase NSE2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients |
| title | Serum E3 SUMO-protein ligase NSE2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients |
| title_full | Serum E3 SUMO-protein ligase NSE2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients |
| title_fullStr | Serum E3 SUMO-protein ligase NSE2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients |
| title_full_unstemmed | Serum E3 SUMO-protein ligase NSE2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients |
| title_short | Serum E3 SUMO-protein ligase NSE2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients |
| title_sort | serum e3 sumo-protein ligase nse2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients |
| topic | R Medicine (General) |
| url | http://irep.iium.edu.my/54726/ http://irep.iium.edu.my/54726/ http://irep.iium.edu.my/54726/ http://irep.iium.edu.my/54726/13/54726_Serum%20E3%20SUMO-protein.pdf http://irep.iium.edu.my/54726/14/54726_Serum%20E3%20SUMO-protein_SCOPUS.pdf |