Methylation status of MGMT and SPOCK2 in diffuse large B-cell lymphoma

QR Code

Methylation status of MGMT and SPOCK2 in diffuse large B-cell lymphoma

MGMT (O6-Methylguanine-DNA Methyltransferase) suppresses tumour development by removing alkyl adduct, while SPOCK2 (SPARC/Osteonectin CWCV and Kazal-like domains proteoglycan) abolishes the inhibition of membrane-type matrix metalloproteinases (MT-MMP) which leads to angiogenesis. Hence, MGMT methyl...

Full description

Bibliographic Details
Main Authors:	Zainuddin, Norafiza, Mohd. Ridah, Lailatul Jalilah, Omar, Aqilah Nabihah, A. Talib, Norlelawati, Muhammad, Naznin, Hussain, Faezatul Arbaeyah
Format:	Proceeding Paper
Language:	English
Published:	2016
Subjects:	RC254 Neoplasms. Tumors. Oncology (including Cancer)
Online Access:	http://irep.iium.edu.my/54375/ http://irep.iium.edu.my/54375/1/54375_abstract.pdf

Similar Items

Methylation-specific PCR Revealed Aberrant Promoter Gene Methylation of p16, MGMT and SPOCK2 in Diffuse Large B-cell Lymphoma
by: Mohd. Ridah, Lailatul Jalilah, et al.
Published: (2015)

Epigenetic methylation status of P16, MGMT and SPOCK2 in diffuse Large B cell lymphoma
by: Mohd. Ridah, Lailatul Jalilah, et al.
Published: (2016)

MGMT and SPOCK2 promoter methylation in diffuse large B-Cell lymphoma: a study in two tertiary health centres in the East Coast of Malaysia = Metilasi promoter MGMT dan SPOCK2 dalam diffuse large B-cell lymphoma: satu kajian yang dijalankan di dua pusat Kesihatan di Pantai Timur Malaysia
by: Zainuddin, Norafiza, et al.
Published: (2017)

Detection of p16INK4a (p16) methylation in diffuse large B-cell lymphoma using methylation-specific PCR
by: Mohd. Ridah, Lailatul Jalilah, et al.
Published: (2014)

Qualitative detection of p16INK4a tumor suppressor gene methylation in diffuse large b-cell lymphoma using methylation-specific PCR
by: Mohd. Ridah, Lailatul Jalilah, et al.
Published: (2014)

Pyrosequencing-based quantitative identification of p16 methylation in diffuse large B-cell lymphoma at two centres in the East Coast of Malaysia
by: Mohd. Ridah, Lailatul Jalilah, et al.
Published: (2016)

p16 tumor suppressor gene methylation in diffuse large B cell lymphoma: a study of 88 cases at two hospitals in the east coast of Malaysia
by: Mohd Ridah, Lailatul Jalilah, et al.
Published: (2017)

MGMT and SPOCK2 promoter methylation in diffuse large B-Cell lymphoma: a study in two tertiary health centres in the East Coast of Malaysia
by: Norafiza Zainuddin,, et al.
Published: (2017)

Quantitative evaluation of p16INK4a promoter methylation using pyrosequencing in de novo diffuse large B-cell lymphoma
by: Zainuddin, Norafiza, et al.
Published: (2011)

TP53 mutations predict for poor survival in de novo diffuse large B-cell lymphoma of germinal center subtype
by: Zainuddin, Norafiza, et al.
Published: (2008)

Molecular genetic analysis in B-cell Lymphomas : a focus on the p53 pathway and p16INK4a
by: Zainuddin, Norafiza
Published: (2010)

The MDM2 polymorphism SNP309 is associated with clinical characteristics and outcome in diffuse large B-cell lymphoma
by: Hedstrom, Gustav, et al.
Published: (2014)

Methylation-sppecific PCR assay for quantification of DNA methylation of SPG20 gene in colorectal cancer
by: Mamat, Maizatul Akma, et al.
Published: (2017)

Expression profile of HIP1R in B-cell subsets and in silico prediction of its functions in diffuse large B-cell lymphoma
by: Keng, Wong Kah
Published: (2018)

Knowledge and perception on lung cancer and its screening: a study among undergraduate students of the International Islamic University Malaysia, Kuantan Campus
by: Zainuddin, Norafiza, et al.
Published: (2017)

Non-neoformans cryptococcemia in a patient with hodgkin’s lymphoma
by: Ding, Chuanhun, et al.
Published: (2018)

Molecular genetic analysis of phosphatase and tensin homolog and p16 tumor suppressor genes in patients with malignant glioma
by: Abdullah, Jafri Malin, et al.
Published: (2003)

Cytotoxicity effect of melastoma malabatricum on skin melanoma and cervical cancer in vitro
by: Ahmad Roslen, Nurfariza, et al.
Published: (2013)

TP53 mutations are infrequent in newly diagnosed chronic lymphocytic leukimia
by: Zainuddin, Norafiza, et al.
Published: (2011)

Lack of association between the MDM2 promoter polymorphism SNP309 and clinical outcome in chronic lymphocytic leukimia
by: Kaderi, Mohd Arifin, et al.
Published: (2010)

Elucidating the epigenetic roles of notch1 in regulating gata3 and C-MYC in peripheral t cell lymphomas
by: Al-Khreisat, Mutaz Jamal Abed
Published: (2024)

Molecular Toxico-Pathology Responses Of EUDRILUS EUGENIAE TO 2- AMINO-l-METHYL-6-PHENYLIMIDAZO[4,5- bJPYRIDINE (PhIP) AND 2-AMINO-3,8- DIMETHYLIMIDAZO [4,5-f]QUINOXALINE (MeIQx)
by: Balogun, Wasiu Gbolahan
Published: (2019)

Epigenetic silencing status of p16INK4a and MGMT promoter regions identified qualitatively in diffuse large B cell lymphoma
by: Mohd Ridah, L Jalilah, et al.
Published: (2015)

Microrna as a potential biomarker in the diagnosis and prognosis of Hodgkin’s lymphoma: a systematic review
by: Nik Izhar, Nik Nurdiyana, et al.
Published: (2019)

Subcellular localization of leptin and leptin receptor in breast cancer detected in an electron microscopic study
by: Abdulrazzaq, Saad Mohammed, et al.
Published: (2016)

Novel derivative of aminobenzenesulfonamide (3c) induces apoptosis in colorectal cancer cells through ROS generation and inhibits cell migration
by: Al-Khayal, Khayal A., et al.
Published: (2017)

Soy intake and breast cancer risk: a meta-analysis of epidemiological studies
by: Bahrom, Suhaila, et al.
Published: (2016)

Extraction and purification of cytotoxic compounds from Premna serratifolia L. (Bebuas) for human breast cancer treatment
by: Salih, Ghassan Ali, et al.
Published: (2016)

Hybrid Imaging-SPECT/CT: making a difference
by: Sayed, Inayatullah Shah, et al.
Published: (2016)

Imbalanced expression of polycistronic miRNA in acute myeloid leukemia
by: Kotaki, Ryutaro, et al.
Published: (2017)

Papillary thyroid cancer: Genetic alterations and molecular biomarker investigations
by: Abdullah, Mardiaty Iryani, et al.
Published: (2019)

Improving patient experience of cancer follow up: redesign and evaluation of adult cancer aftercare services for breast, colorectal, and testicular patients, at University Hospital Southampton NHS Foundation Trust
by: Batehup, Lynn, et al.
Published: (2014)

Health-related quality of life after colorectal cancer in England: a patient-reported outcomes study of individuals 12 to 36 months after diagnosis
by: Downing, Amy, et al.
Published: (2015)

An undiagnosed non functioning retroperitoneum paraganglioma, complicating a gynaecological surgery; a case report
by: Abd. Wahab, Noraziana, et al.
Published: (2010)

Intrapelvic Wilms' tumour: a rare entity for the most commonly encountered malignant renal tumour in children
by: Abd. Aziz, Azian, et al.
Published: (2010)

Renal cell carcinoma in a von Hippel-Lindau syndrome; when should pheochromocytoma be anticipated?
by: Mohd Shah, Azarisman Shah, et al.
Published: (2007)

Influence of support group intervention on quality of life of Malaysian breast cancer survivors
by: Abu Kassim , Noor Lide, et al.
Published: (2013)

Translation termination mutations analysis using the protein truncation test on exon11A of the BRCA1 gene in female breast cancer patients of Pahang, Malaysia
by: Alattraqchi, Ahmed G., et al.
Published: (2012)

2nd EORTC Symposium: Quality of life, symptom research and patient-reported outcomes in cancer clinical trials. Travelling fellows brief report
by: Sharifudin, Mohd Ariff
Published: (2012)

Causal links in QOL sub-domains accentuate greater support for physical and emotional well-being of breast cancer survivors
by: Abu Kassim , Noor Lide, et al.
Published: (2010)