Synthesis and characterization of spermidine containing sulphur
Studies in compound containing sulphur and the polyamine transport system is beneficial in oncology as both affect cancer cells. Compounds containing sulphur such as organosulphur are known for their anti-cancer properties. The polyamine transport system however is known for its ability to interact...
| Main Authors: | , , |
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| Format: | Proceeding Paper |
| Language: | English |
| Published: |
Penerbit UMT, Universiti Malaysia Terengganu (UMT)
2016
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/53900/ http://irep.iium.edu.my/53900/1/53900_Synthesize%20and%20Characterization%20of%20Spermidine.pdf |
| _version_ | 1848784310733111296 |
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| author | Sahabudin, Adzly Hairee How, Fiona Ni Foong Abdul Ghani, Radiah |
| author_facet | Sahabudin, Adzly Hairee How, Fiona Ni Foong Abdul Ghani, Radiah |
| author_sort | Sahabudin, Adzly Hairee |
| building | IIUM Repository |
| collection | Online Access |
| description | Studies in compound containing sulphur and the polyamine transport system is beneficial in oncology as both affect cancer cells. Compounds containing sulphur such as organosulphur are known for their anti-cancer properties. The polyamine transport system however is known for its ability to interact with cancer cells directly. By adding sulphur to known natural polyamine, the resulting compound is anticipated to retain both properties. One of the widely used of polyamine moiety is used as the cell delivery vector to transport sulphur to the targeted cancer cells. In this study, the spermidine containing sulphur was synthesized by adding carbon disulphide atoms to spermidine atom. The compound was then characterized and analyzed to determine its physiochemical properties and chemical structure. Determination on the characteristic and chemical structure of the compounds were carried out using various techniques such Fourier transformed infrared spectroscopy, thin layer chromatography and gas chromatography mass spectroscopy. |
| first_indexed | 2025-11-14T16:35:13Z |
| format | Proceeding Paper |
| id | iium-53900 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T16:35:13Z |
| publishDate | 2016 |
| publisher | Penerbit UMT, Universiti Malaysia Terengganu (UMT) |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-539002017-05-17T06:26:52Z http://irep.iium.edu.my/53900/ Synthesis and characterization of spermidine containing sulphur Sahabudin, Adzly Hairee How, Fiona Ni Foong Abdul Ghani, Radiah QD Chemistry Studies in compound containing sulphur and the polyamine transport system is beneficial in oncology as both affect cancer cells. Compounds containing sulphur such as organosulphur are known for their anti-cancer properties. The polyamine transport system however is known for its ability to interact with cancer cells directly. By adding sulphur to known natural polyamine, the resulting compound is anticipated to retain both properties. One of the widely used of polyamine moiety is used as the cell delivery vector to transport sulphur to the targeted cancer cells. In this study, the spermidine containing sulphur was synthesized by adding carbon disulphide atoms to spermidine atom. The compound was then characterized and analyzed to determine its physiochemical properties and chemical structure. Determination on the characteristic and chemical structure of the compounds were carried out using various techniques such Fourier transformed infrared spectroscopy, thin layer chromatography and gas chromatography mass spectroscopy. Penerbit UMT, Universiti Malaysia Terengganu (UMT) 2016-11-31 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/53900/1/53900_Synthesize%20and%20Characterization%20of%20Spermidine.pdf Sahabudin, Adzly Hairee and How, Fiona Ni Foong and Abdul Ghani, Radiah (2016) Synthesis and characterization of spermidine containing sulphur. In: 13th Universiti Malaysia Terengganu International Annual Symposium on Sustainability Science and Management (UMTAS 2016), 13th-15th Dec. 2016, Kuala Terengganu. http://umtas2016.umt.edu.my/?page_id=210 |
| spellingShingle | QD Chemistry Sahabudin, Adzly Hairee How, Fiona Ni Foong Abdul Ghani, Radiah Synthesis and characterization of spermidine containing sulphur |
| title | Synthesis and characterization of spermidine containing sulphur |
| title_full | Synthesis and characterization of spermidine containing sulphur |
| title_fullStr | Synthesis and characterization of spermidine containing sulphur |
| title_full_unstemmed | Synthesis and characterization of spermidine containing sulphur |
| title_short | Synthesis and characterization of spermidine containing sulphur |
| title_sort | synthesis and characterization of spermidine containing sulphur |
| topic | QD Chemistry |
| url | http://irep.iium.edu.my/53900/ http://irep.iium.edu.my/53900/ http://irep.iium.edu.my/53900/1/53900_Synthesize%20and%20Characterization%20of%20Spermidine.pdf |