The mode of antimicrobial action of Cinnamomum burmannii’s essential oil & cinnamaldehyde

The aim of this study was to postulate the mode of antimicrobial actions of both essential oil and cinnamaldehyde from Cinnamomum burmannii on the cell membrane of Escherichia coli, Staphylococcus aureus and Candida albicans. The essential oil was extracted by steam distillation and followed by t...

Full description

Bibliographic Details
Main Authors: Awang, Anis Fadhlina Izyani, Bakhtiar, M. Taher, Darnis, Deny Susanti
Format: Article
Language:English
English
English
Published: Universiti Teknologi Malaysia 2016
Subjects:
Online Access:http://irep.iium.edu.my/53158/
http://irep.iium.edu.my/53158/7/53158_The%20mode%20of%20antimicrobial%20action%20of%20Cinnamomum_Scopus.pdf
http://irep.iium.edu.my/53158/13/53158_The%20mode%20of%20antimicrobial%20action.pdf
http://irep.iium.edu.my/53158/14/53158_The%20mode%20of%20antimicrobial%20action_WOS.pdf
_version_ 1848784187320958976
author Awang, Anis Fadhlina Izyani
Bakhtiar, M. Taher
Darnis, Deny Susanti
author_facet Awang, Anis Fadhlina Izyani
Bakhtiar, M. Taher
Darnis, Deny Susanti
author_sort Awang, Anis Fadhlina Izyani
building IIUM Repository
collection Online Access
description The aim of this study was to postulate the mode of antimicrobial actions of both essential oil and cinnamaldehyde from Cinnamomum burmannii on the cell membrane of Escherichia coli, Staphylococcus aureus and Candida albicans. The essential oil was extracted by steam distillation and followed by the isolation of cinnamaldehyde. Four modes of action were tested including time-killing assay, salt tolerance assay, crystal violet assay and leakage of cellular metabolites. The antimicrobial effect on the cell membrane was dose-dependent whereby stronger antimicrobial action was observed by cinnamaldehyde at concentration equal to 4×MIC (1.33 mg/mL) compared to the essential oil. The potential of cinnamaldehyde as an antimicrobial compound of the cinnamon essential oil was discovered and proven to act on the cell membrane of tested microorganisms particularly against C. albicans.
first_indexed 2025-11-14T16:33:15Z
format Article
id iium-53158
institution International Islamic University Malaysia
institution_category Local University
language English
English
English
last_indexed 2025-11-14T16:33:15Z
publishDate 2016
publisher Universiti Teknologi Malaysia
recordtype eprints
repository_type Digital Repository
spelling iium-531582022-11-08T05:01:57Z http://irep.iium.edu.my/53158/ The mode of antimicrobial action of Cinnamomum burmannii’s essential oil & cinnamaldehyde Awang, Anis Fadhlina Izyani Bakhtiar, M. Taher Darnis, Deny Susanti QD Chemistry The aim of this study was to postulate the mode of antimicrobial actions of both essential oil and cinnamaldehyde from Cinnamomum burmannii on the cell membrane of Escherichia coli, Staphylococcus aureus and Candida albicans. The essential oil was extracted by steam distillation and followed by the isolation of cinnamaldehyde. Four modes of action were tested including time-killing assay, salt tolerance assay, crystal violet assay and leakage of cellular metabolites. The antimicrobial effect on the cell membrane was dose-dependent whereby stronger antimicrobial action was observed by cinnamaldehyde at concentration equal to 4×MIC (1.33 mg/mL) compared to the essential oil. The potential of cinnamaldehyde as an antimicrobial compound of the cinnamon essential oil was discovered and proven to act on the cell membrane of tested microorganisms particularly against C. albicans. Universiti Teknologi Malaysia 2016-11 Article PeerReviewed application/pdf en http://irep.iium.edu.my/53158/7/53158_The%20mode%20of%20antimicrobial%20action%20of%20Cinnamomum_Scopus.pdf application/pdf en http://irep.iium.edu.my/53158/13/53158_The%20mode%20of%20antimicrobial%20action.pdf application/pdf en http://irep.iium.edu.my/53158/14/53158_The%20mode%20of%20antimicrobial%20action_WOS.pdf Awang, Anis Fadhlina Izyani and Bakhtiar, M. Taher and Darnis, Deny Susanti (2016) The mode of antimicrobial action of Cinnamomum burmannii’s essential oil & cinnamaldehyde. Jurnal Teknologi, 78 (11). pp. 41-47. E-ISSN 2180-3722 http://www.jurnalteknologi.utm.my/index.php/jurnalteknologi/article/view/9942/5980 10.11113/jt.v78.9942
spellingShingle QD Chemistry
Awang, Anis Fadhlina Izyani
Bakhtiar, M. Taher
Darnis, Deny Susanti
The mode of antimicrobial action of Cinnamomum burmannii’s essential oil & cinnamaldehyde
title The mode of antimicrobial action of Cinnamomum burmannii’s essential oil & cinnamaldehyde
title_full The mode of antimicrobial action of Cinnamomum burmannii’s essential oil & cinnamaldehyde
title_fullStr The mode of antimicrobial action of Cinnamomum burmannii’s essential oil & cinnamaldehyde
title_full_unstemmed The mode of antimicrobial action of Cinnamomum burmannii’s essential oil & cinnamaldehyde
title_short The mode of antimicrobial action of Cinnamomum burmannii’s essential oil & cinnamaldehyde
title_sort mode of antimicrobial action of cinnamomum burmannii’s essential oil & cinnamaldehyde
topic QD Chemistry
url http://irep.iium.edu.my/53158/
http://irep.iium.edu.my/53158/
http://irep.iium.edu.my/53158/
http://irep.iium.edu.my/53158/7/53158_The%20mode%20of%20antimicrobial%20action%20of%20Cinnamomum_Scopus.pdf
http://irep.iium.edu.my/53158/13/53158_The%20mode%20of%20antimicrobial%20action.pdf
http://irep.iium.edu.my/53158/14/53158_The%20mode%20of%20antimicrobial%20action_WOS.pdf