High occurrence of CYP3A5 variants among breast cancer and organ transplant patients

High occurrence of CYP3A5 variants among breast cancer and organ transplant patients

Abstract CYP3A5 is one of the important drug metabolising enzyme and its polymorphism shows marked differences in protein expression and catalytic activities between different geographical ethnic groups. Both tamoxifen and tacrolimus are substrates of CYP3A5 and thus the polymorphism may cause phar...

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Bibliographic Details
Main Authors: Ismail, S, Mohammad, NI, Hamzah, S, Mohamad , R, Harun, R, Suhaimi, S, Jaszle, S, Sood, S, Henry, F, Shabery, A, Rajoo, T, Bahri, R, Muniandy, S, Ismail, G, Wong, H. S., Abdullah Ngow, Harris, U Kyaw, T. H., Jalaludin, K, Din, J, Hatta, F. H., Teh, L. K., Salleh, M. Z.
Format: Proceeding Paper
Language:English
Published: 2010
Subjects:
RB Pathology
RC Internal medicine
Online Access:http://irep.iium.edu.my/5235/
http://irep.iium.edu.my/5235/1/Abstract_for_NCCR_2010_cyp3a5a.pdf

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