Electrochemical characterization of polylactic acid-block-poly(2-vinylpyridine)/gold nanoparticle (aunp) composites for glucose biosensor development
Nanocomposites that consist of diblock copolymer (BCP) and gold nanoparticles (AuNPs) can be applied as a suitable matrix to immobilize enzymes or other molecules based on the well-defined core/shell nanostructures of these composites. In this research, polylactic acid-block-poly(2-vinylpyridine)...
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| Format: | Proceeding Paper |
| Language: | English |
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Kulliyah of Engineering, International Islamic University Malaysia
2016
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| Online Access: | http://irep.iium.edu.my/51784/ http://irep.iium.edu.my/51784/1/51784.pdf |
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| author | Long, JiaJia Wan Salim, Wan Wardatul Amani Ali, Fathilah |
| author_facet | Long, JiaJia Wan Salim, Wan Wardatul Amani Ali, Fathilah |
| author_sort | Long, JiaJia |
| building | IIUM Repository |
| collection | Online Access |
| description | Nanocomposites that consist of diblock copolymer (BCP) and gold nanoparticles (AuNPs) can be applied as a
suitable matrix to immobilize enzymes or other molecules based on the well-defined core/shell nanostructures
of these composites. In this research, polylactic acid-block-poly(2-vinylpyridine) (PLA-b-P2VP)/hydrogen
tetrachloroaurate(III) hydrate (HAuCl4.3H2O) composites were hybridized and then reduced in
dichloromethane (DCM) solution. The hybridizations between gold precursors and the P2VP domain were
prepared with different ratios of gold to P2VP block (1:1, 1:5, 1:10, 5:1, 10:1) by taking advantage of the
association between the long-pair nitrogen of the pyridine group of P2VP. The reduction of the Au3+/PLA-bP2VP
composite was accomplished by hydrazine solution in order to get gold nanoparticle/PLA-b-P2VP
composites, visually confirmed by a direct color change from bright yellow to purple. In this work,
ultraviolet–visible (UV-vis) spectroscopy and Fourier transform infrared spectroscopy (FTIR) were used to
confirm the association between gold precursors and pyridine groups as well as the synthesis of gold
nanoparticles. Furthermore, the electrochemical properties of gold nanoparticle/BCP composites with
different ratios were obtained via cyclic voltammetry measurement. This composite has high potential to be
used in the development of a glucose biosensor. |
| first_indexed | 2025-11-14T16:29:12Z |
| format | Proceeding Paper |
| id | iium-51784 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T16:29:12Z |
| publishDate | 2016 |
| publisher | Kulliyah of Engineering, International Islamic University Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-517842016-08-24T03:24:01Z http://irep.iium.edu.my/51784/ Electrochemical characterization of polylactic acid-block-poly(2-vinylpyridine)/gold nanoparticle (aunp) composites for glucose biosensor development Long, JiaJia Wan Salim, Wan Wardatul Amani Ali, Fathilah TP248.13 Biotechnology Nanocomposites that consist of diblock copolymer (BCP) and gold nanoparticles (AuNPs) can be applied as a suitable matrix to immobilize enzymes or other molecules based on the well-defined core/shell nanostructures of these composites. In this research, polylactic acid-block-poly(2-vinylpyridine) (PLA-b-P2VP)/hydrogen tetrachloroaurate(III) hydrate (HAuCl4.3H2O) composites were hybridized and then reduced in dichloromethane (DCM) solution. The hybridizations between gold precursors and the P2VP domain were prepared with different ratios of gold to P2VP block (1:1, 1:5, 1:10, 5:1, 10:1) by taking advantage of the association between the long-pair nitrogen of the pyridine group of P2VP. The reduction of the Au3+/PLA-bP2VP composite was accomplished by hydrazine solution in order to get gold nanoparticle/PLA-b-P2VP composites, visually confirmed by a direct color change from bright yellow to purple. In this work, ultraviolet–visible (UV-vis) spectroscopy and Fourier transform infrared spectroscopy (FTIR) were used to confirm the association between gold precursors and pyridine groups as well as the synthesis of gold nanoparticles. Furthermore, the electrochemical properties of gold nanoparticle/BCP composites with different ratios were obtained via cyclic voltammetry measurement. This composite has high potential to be used in the development of a glucose biosensor. Kulliyah of Engineering, International Islamic University Malaysia 2016 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/51784/1/51784.pdf Long, JiaJia and Wan Salim, Wan Wardatul Amani and Ali, Fathilah (2016) Electrochemical characterization of polylactic acid-block-poly(2-vinylpyridine)/gold nanoparticle (aunp) composites for glucose biosensor development. In: 4th International Conference on Biotechnology Engineering 2016 (ICBioE 2016), 25th-27th July 2016, Kuala Lumpur. http://www.iium.edu.my/icbioe/2016/ |
| spellingShingle | TP248.13 Biotechnology Long, JiaJia Wan Salim, Wan Wardatul Amani Ali, Fathilah Electrochemical characterization of polylactic acid-block-poly(2-vinylpyridine)/gold nanoparticle (aunp) composites for glucose biosensor development |
| title | Electrochemical characterization of polylactic acid-block-poly(2-vinylpyridine)/gold nanoparticle (aunp) composites for glucose biosensor development |
| title_full | Electrochemical characterization of polylactic acid-block-poly(2-vinylpyridine)/gold nanoparticle (aunp) composites for glucose biosensor development |
| title_fullStr | Electrochemical characterization of polylactic acid-block-poly(2-vinylpyridine)/gold nanoparticle (aunp) composites for glucose biosensor development |
| title_full_unstemmed | Electrochemical characterization of polylactic acid-block-poly(2-vinylpyridine)/gold nanoparticle (aunp) composites for glucose biosensor development |
| title_short | Electrochemical characterization of polylactic acid-block-poly(2-vinylpyridine)/gold nanoparticle (aunp) composites for glucose biosensor development |
| title_sort | electrochemical characterization of polylactic acid-block-poly(2-vinylpyridine)/gold nanoparticle (aunp) composites for glucose biosensor development |
| topic | TP248.13 Biotechnology |
| url | http://irep.iium.edu.my/51784/ http://irep.iium.edu.my/51784/ http://irep.iium.edu.my/51784/1/51784.pdf |