Application of multivariate data analysis for rapid identification of flavonoids classes

Bioactive compounds are one of the natural products used especially for medicinal, pharmaceutical and food application. Increasing research performed on the extraction, isolation and identification of bioactive compounds, however non to date has explored on the identification of flavonoids classes...

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Main Authors: Che Noh, Che Hafizah, Mohamed Azmin, Nor Fadhillah, Amid, Azura, Asnawi, Ani Liza
Format: Proceeding Paper
Language:English
Published: Kulliyah of Engineering, International Islamic University Malaysia 2016
Subjects:
Online Access:http://irep.iium.edu.my/51673/
http://irep.iium.edu.my/51673/1/51673.pdf
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author Che Noh, Che Hafizah
Mohamed Azmin, Nor Fadhillah
Amid, Azura
Asnawi, Ani Liza
author_facet Che Noh, Che Hafizah
Mohamed Azmin, Nor Fadhillah
Amid, Azura
Asnawi, Ani Liza
author_sort Che Noh, Che Hafizah
building IIUM Repository
collection Online Access
description Bioactive compounds are one of the natural products used especially for medicinal, pharmaceutical and food application. Increasing research performed on the extraction, isolation and identification of bioactive compounds, however non to date has explored on the identification of flavonoids classes. Therefore, this study was focused on the development of algorithm for rapid identification of flavonoids classes which are flavanone, flavone and flavonol. Fourier Transform Infrared (FTIR) spectroscopy coupled with multivariate statistical data analysis, which is Principal Component Analysis (PCA) was performed. The results showed that the flavonoids classes were identified according to spectral region assigned using the PCA algorithm based on the FTIR spectrum of the samples. The study concluded that FTIR coupled with PCA analysis can be used as a molecular fingerprint for rapid identification of flavonoids classes. The comparative studies of other flavonoids classes are still under investigation using the same method.
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format Proceeding Paper
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institution International Islamic University Malaysia
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language English
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publishDate 2016
publisher Kulliyah of Engineering, International Islamic University Malaysia
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spelling iium-516732017-07-12T04:38:54Z http://irep.iium.edu.my/51673/ Application of multivariate data analysis for rapid identification of flavonoids classes Che Noh, Che Hafizah Mohamed Azmin, Nor Fadhillah Amid, Azura Asnawi, Ani Liza QK Botany T Technology (General) Bioactive compounds are one of the natural products used especially for medicinal, pharmaceutical and food application. Increasing research performed on the extraction, isolation and identification of bioactive compounds, however non to date has explored on the identification of flavonoids classes. Therefore, this study was focused on the development of algorithm for rapid identification of flavonoids classes which are flavanone, flavone and flavonol. Fourier Transform Infrared (FTIR) spectroscopy coupled with multivariate statistical data analysis, which is Principal Component Analysis (PCA) was performed. The results showed that the flavonoids classes were identified according to spectral region assigned using the PCA algorithm based on the FTIR spectrum of the samples. The study concluded that FTIR coupled with PCA analysis can be used as a molecular fingerprint for rapid identification of flavonoids classes. The comparative studies of other flavonoids classes are still under investigation using the same method. Kulliyah of Engineering, International Islamic University Malaysia 2016 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/51673/1/51673.pdf Che Noh, Che Hafizah and Mohamed Azmin, Nor Fadhillah and Amid, Azura and Asnawi, Ani Liza (2016) Application of multivariate data analysis for rapid identification of flavonoids classes. In: 4th International Conference on Biotechnology Engineering 2016 (ICBioE 2016), 25th-27th July 2016, Kuala Lumpur.
spellingShingle QK Botany
T Technology (General)
Che Noh, Che Hafizah
Mohamed Azmin, Nor Fadhillah
Amid, Azura
Asnawi, Ani Liza
Application of multivariate data analysis for rapid identification of flavonoids classes
title Application of multivariate data analysis for rapid identification of flavonoids classes
title_full Application of multivariate data analysis for rapid identification of flavonoids classes
title_fullStr Application of multivariate data analysis for rapid identification of flavonoids classes
title_full_unstemmed Application of multivariate data analysis for rapid identification of flavonoids classes
title_short Application of multivariate data analysis for rapid identification of flavonoids classes
title_sort application of multivariate data analysis for rapid identification of flavonoids classes
topic QK Botany
T Technology (General)
url http://irep.iium.edu.my/51673/
http://irep.iium.edu.my/51673/1/51673.pdf