Primary pigmented nodular adrenocortical disease
Primary pigmented nodular adrenocortical disease (PPNAD) is a rare adrenal tumour causing corticotrophin-independent Cushing's syndrome. It occurs mainly in children and young adults. The histological examination is characterised by small pigmented micronodules on the adrenal cortex. The diagno...
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| Format: | Article |
| Language: | English |
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The Polish Society of Endocrinology
2011
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| Online Access: | http://irep.iium.edu.my/5111/ http://irep.iium.edu.my/5111/1/EP.2011.3_17_Ngow.pdf |
| _version_ | 1848776447279235072 |
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| author | Ngow, Harris Abdullah Khairina, Wan Mohd Nowalid Wan |
| author_facet | Ngow, Harris Abdullah Khairina, Wan Mohd Nowalid Wan |
| author_sort | Ngow, Harris Abdullah |
| building | IIUM Repository |
| collection | Online Access |
| description | Primary pigmented nodular adrenocortical disease (PPNAD) is a rare adrenal tumour causing corticotrophin-independent Cushing's syndrome. It occurs mainly in children and young adults. The histological examination is characterised by small pigmented micronodules on the adrenal cortex. The diagnosis is most often seen in patients with Carney Complex, but it can also occur in isolation. We report a case of Carney Complex that was referred for adrenalectomy. The procedure was uneventful and the patient was well at discharge. The adrenal pathology showed numerous black nodules measuring less than 2mm in diameter. This feature was pathognomonic of primary pigmented nodular adrenocortical disease. |
| first_indexed | 2025-11-14T14:30:14Z |
| format | Article |
| id | iium-5111 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T14:30:14Z |
| publishDate | 2011 |
| publisher | The Polish Society of Endocrinology |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-51112011-10-28T05:20:02Z http://irep.iium.edu.my/5111/ Primary pigmented nodular adrenocortical disease Ngow, Harris Abdullah Khairina, Wan Mohd Nowalid Wan RB Pathology RC Internal medicine Primary pigmented nodular adrenocortical disease (PPNAD) is a rare adrenal tumour causing corticotrophin-independent Cushing's syndrome. It occurs mainly in children and young adults. The histological examination is characterised by small pigmented micronodules on the adrenal cortex. The diagnosis is most often seen in patients with Carney Complex, but it can also occur in isolation. We report a case of Carney Complex that was referred for adrenalectomy. The procedure was uneventful and the patient was well at discharge. The adrenal pathology showed numerous black nodules measuring less than 2mm in diameter. This feature was pathognomonic of primary pigmented nodular adrenocortical disease. The Polish Society of Endocrinology 2011 Article PeerReviewed application/pdf en http://irep.iium.edu.my/5111/1/EP.2011.3_17_Ngow.pdf Ngow, Harris Abdullah and Khairina, Wan Mohd Nowalid Wan (2011) Primary pigmented nodular adrenocortical disease. Endokrynologia Polska/ Polish Journal of Endocrinology, 62 (3). pp. 268-70. ISSN 0423-104X http://www.endokrynologia.polska.viamedica.pl |
| spellingShingle | RB Pathology RC Internal medicine Ngow, Harris Abdullah Khairina, Wan Mohd Nowalid Wan Primary pigmented nodular adrenocortical disease |
| title | Primary pigmented nodular adrenocortical disease |
| title_full | Primary pigmented nodular adrenocortical disease |
| title_fullStr | Primary pigmented nodular adrenocortical disease |
| title_full_unstemmed | Primary pigmented nodular adrenocortical disease |
| title_short | Primary pigmented nodular adrenocortical disease |
| title_sort | primary pigmented nodular adrenocortical disease |
| topic | RB Pathology RC Internal medicine |
| url | http://irep.iium.edu.my/5111/ http://irep.iium.edu.my/5111/ http://irep.iium.edu.my/5111/1/EP.2011.3_17_Ngow.pdf |