A case of successful Thrombolysis in Pulmonary Embolism with Tenecteplase During Peripartum Period
Tenecteplase is a recognized thrombolytic therapy for myocardial infarction. It is also increasingly used in massive and submassive pulmonary embolism. Thus far, there had been 22 patients with pulmonary embolism treated with tenecteplase. However, none of the patients was treated during peripartum...
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| Format: | Article |
| Language: | English |
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Republic of China Society of Cardiology
2011
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| Online Access: | http://irep.iium.edu.my/5106/ http://irep.iium.edu.my/5106/1/ACS_TNK_in_Pulm_Embolism.pdf |
| _version_ | 1848776446057644032 |
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| author | Ngow, Harris Abdullah Wan Nowalid, Wan Khairina |
| author_facet | Ngow, Harris Abdullah Wan Nowalid, Wan Khairina |
| author_sort | Ngow, Harris Abdullah |
| building | IIUM Repository |
| collection | Online Access |
| description | Tenecteplase is a recognized thrombolytic therapy for myocardial infarction. It is also increasingly used in massive and submassive pulmonary embolism. Thus far, there had been 22 patients with pulmonary embolism treated with tenecteplase. However, none of the patients was treated during peripartum period. We report its use in a 35-year-old multiparous woman who was referred at 4 hours post partum with cardiogenic shock. She was clinically suspected to have acute pulmonary embolism, and this was confirmed by computed tomography of the pulmonary artery. She was successfully thrombolysed with tenecteplase but suffered bleeding complication. She was resuscitated and remained stable until discharge 1 week later. A repeat computed tomography of the pulmonary artery at day 4 post-thrombolysis showed a significant reduction in the thrombus load. This case illustrates the potential benefit and efficacy of tenecteplase in acute pulmonary embolism in peri-partum women.
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| first_indexed | 2025-11-14T14:30:13Z |
| format | Article |
| id | iium-5106 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T14:30:13Z |
| publishDate | 2011 |
| publisher | Republic of China Society of Cardiology |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-51062013-06-19T07:52:46Z http://irep.iium.edu.my/5106/ A case of successful Thrombolysis in Pulmonary Embolism with Tenecteplase During Peripartum Period Ngow, Harris Abdullah Wan Nowalid, Wan Khairina R Medicine (General) RC Internal medicine RM Therapeutics. Pharmacology Tenecteplase is a recognized thrombolytic therapy for myocardial infarction. It is also increasingly used in massive and submassive pulmonary embolism. Thus far, there had been 22 patients with pulmonary embolism treated with tenecteplase. However, none of the patients was treated during peripartum period. We report its use in a 35-year-old multiparous woman who was referred at 4 hours post partum with cardiogenic shock. She was clinically suspected to have acute pulmonary embolism, and this was confirmed by computed tomography of the pulmonary artery. She was successfully thrombolysed with tenecteplase but suffered bleeding complication. She was resuscitated and remained stable until discharge 1 week later. A repeat computed tomography of the pulmonary artery at day 4 post-thrombolysis showed a significant reduction in the thrombus load. This case illustrates the potential benefit and efficacy of tenecteplase in acute pulmonary embolism in peri-partum women. Republic of China Society of Cardiology 2011-03-01 Article PeerReviewed application/pdf en http://irep.iium.edu.my/5106/1/ACS_TNK_in_Pulm_Embolism.pdf Ngow, Harris Abdullah and Wan Nowalid, Wan Khairina (2011) A case of successful Thrombolysis in Pulmonary Embolism with Tenecteplase During Peripartum Period. Acta Cardiologica Sinica, 27 (1). pp. 52-55. ISSN 1011-6842 http://www.airitilibrary.com/searchdetail.aspx?DocIDs=10116842-201103-201103240017-201103240017-52-55 |
| spellingShingle | R Medicine (General) RC Internal medicine RM Therapeutics. Pharmacology Ngow, Harris Abdullah Wan Nowalid, Wan Khairina A case of successful Thrombolysis in Pulmonary Embolism with Tenecteplase During Peripartum Period |
| title | A case of successful Thrombolysis in Pulmonary Embolism with Tenecteplase During Peripartum Period |
| title_full | A case of successful Thrombolysis in Pulmonary Embolism with Tenecteplase During Peripartum Period |
| title_fullStr | A case of successful Thrombolysis in Pulmonary Embolism with Tenecteplase During Peripartum Period |
| title_full_unstemmed | A case of successful Thrombolysis in Pulmonary Embolism with Tenecteplase During Peripartum Period |
| title_short | A case of successful Thrombolysis in Pulmonary Embolism with Tenecteplase During Peripartum Period |
| title_sort | case of successful thrombolysis in pulmonary embolism with tenecteplase during peripartum period |
| topic | R Medicine (General) RC Internal medicine RM Therapeutics. Pharmacology |
| url | http://irep.iium.edu.my/5106/ http://irep.iium.edu.my/5106/ http://irep.iium.edu.my/5106/1/ACS_TNK_in_Pulm_Embolism.pdf |