Influence of lipids on the hydrophobic barrier within the pore of the TWIK-1 K2P channel

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Influence of lipids on the hydrophobic barrier within the pore of the TWIK-1 K2P channel

Several recent ion channel structures have revealed large side portals, or ‘fenestrations’ at the interface between their transmembrane helices that potentially expose the ion conduction pathway to the lipid core of the bilayer. In a recent study we demonstrated that functional activity of the TWIK-...

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Bibliographic Details
Main Authors:	Aryal, Prafulla, Abd. Wahab, Mohd. Firdaus, Bucci, Giovanna, Sansom, Mark S.P., Tucker, Stephen J.
Format:	Article
Language:	English
Published:	Taylor and Francis Group, LLC 2015
Subjects:	Q Science (General) QP Physiology
Online Access:	http://irep.iium.edu.my/50082/ http://irep.iium.edu.my/50082/1/50082.pdf

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