Bromelain enzyme assay using Casen as substrate

This procedure is following Sigma's non-specific protease activity. In this assay, casein acts as a substrate to the reaction. When protease digest casein, the amino acid tyrosine is liberated along with other amino acids and peptide fragments. Folin & Ciocalteus Phenol, or Folin's rea...

Full description

Bibliographic Details
Main Authors: Amid, Azura, Jamaluddin, Mohd Jamil Aizat
Format: Book Chapter
Language:English
Published: IIUM Press 2016
Subjects:
Online Access:http://irep.iium.edu.my/49849/
http://irep.iium.edu.my/49849/1/49849_Bromelain_enzyme_assay_using_casein.pdf
_version_ 1848783526973931520
author Amid, Azura
Jamaluddin, Mohd Jamil Aizat
author_facet Amid, Azura
Jamaluddin, Mohd Jamil Aizat
author_sort Amid, Azura
building IIUM Repository
collection Online Access
description This procedure is following Sigma's non-specific protease activity. In this assay, casein acts as a substrate to the reaction. When protease digest casein, the amino acid tyrosine is liberated along with other amino acids and peptide fragments. Folin & Ciocalteus Phenol, or Folin's reagent primarily reacts with free tyrosine to produce a blue colored chromophore, which is quantifiable and measured as an absorbance value on the spectrophotometer at 660 nm absorbance. The more tyrosine that is released from the casein, the more chromophores are generated and the stronger the activity of the protease.
first_indexed 2025-11-14T16:22:46Z
format Book Chapter
id iium-49849
institution International Islamic University Malaysia
institution_category Local University
language English
last_indexed 2025-11-14T16:22:46Z
publishDate 2016
publisher IIUM Press
recordtype eprints
repository_type Digital Repository
spelling iium-498492017-02-21T02:05:49Z http://irep.iium.edu.my/49849/ Bromelain enzyme assay using Casen as substrate Amid, Azura Jamaluddin, Mohd Jamil Aizat TP248.13 Biotechnology This procedure is following Sigma's non-specific protease activity. In this assay, casein acts as a substrate to the reaction. When protease digest casein, the amino acid tyrosine is liberated along with other amino acids and peptide fragments. Folin & Ciocalteus Phenol, or Folin's reagent primarily reacts with free tyrosine to produce a blue colored chromophore, which is quantifiable and measured as an absorbance value on the spectrophotometer at 660 nm absorbance. The more tyrosine that is released from the casein, the more chromophores are generated and the stronger the activity of the protease. IIUM Press 2016 Book Chapter PeerReviewed application/pdf en http://irep.iium.edu.my/49849/1/49849_Bromelain_enzyme_assay_using_casein.pdf Amid, Azura and Jamaluddin, Mohd Jamil Aizat (2016) Bromelain enzyme assay using Casen as substrate. In: Experimental methods in modern biotechnology Volume 2. IIUM Press Series of Textbook from the Islamic Perspectives, 2 . IIUM Press, Kuala Lumpur, pp. 100-150. ISBN 978-967-418-384-4 http://iiumpress.iium.edu.my/bookshop/experimental-methods-in-modern-biotechnology
spellingShingle TP248.13 Biotechnology
Amid, Azura
Jamaluddin, Mohd Jamil Aizat
Bromelain enzyme assay using Casen as substrate
title Bromelain enzyme assay using Casen as substrate
title_full Bromelain enzyme assay using Casen as substrate
title_fullStr Bromelain enzyme assay using Casen as substrate
title_full_unstemmed Bromelain enzyme assay using Casen as substrate
title_short Bromelain enzyme assay using Casen as substrate
title_sort bromelain enzyme assay using casen as substrate
topic TP248.13 Biotechnology
url http://irep.iium.edu.my/49849/
http://irep.iium.edu.my/49849/
http://irep.iium.edu.my/49849/1/49849_Bromelain_enzyme_assay_using_casein.pdf