Adrenal insufficiency resulting from Histoplasmosis infiltration in an immunocompetent patient
Histoplasmosis usually affects immunocompromised patients. Histoplasmosis infiltration to the adrenal in an immunocompetent host is rare, more so those who presented with adrenal insufficiency. We report a case of 54-year-old previously fit and healthy man who presented with chronic headache of tw...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Ministry of Health and Universiti Brunei Darussalem
2015
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| Online Access: | http://irep.iium.edu.my/49649/ http://irep.iium.edu.my/49649/1/Bimj2015115261.pdf |
| _version_ | 1848783493008457728 |
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| author | Shahar, Mohammad Arif Ab Wahab, Norasyikin AbAziz, Aini Omar , Ahmad Marzuki Mohd Rusly, Noor Ashikin Kamaruddin, Nor Azmi |
| author_facet | Shahar, Mohammad Arif Ab Wahab, Norasyikin AbAziz, Aini Omar , Ahmad Marzuki Mohd Rusly, Noor Ashikin Kamaruddin, Nor Azmi |
| author_sort | Shahar, Mohammad Arif |
| building | IIUM Repository |
| collection | Online Access |
| description | Histoplasmosis usually affects immunocompromised patients. Histoplasmosis infiltration to the adrenal
in an immunocompetent host is rare, more so those who presented with adrenal insufficiency. We report
a case of 54-year-old previously fit and healthy man who presented with chronic headache of two
months duration that was associated with loss of appetite and weight-loss. He had hypotension, hyponatremia,
relative hyperkalemia with morning cortisol of 160 nmol/L. Computed tomography of the
adrenals showed bilateral enlarged adrenal glands and biopsy confirmed histoplasmosis infiltration.
Treatment successfully ameliorate symptoms of hypocortisolism. This case illustrates that immunocompetent
patient is still susceptible to adrenal histoplasmosis resulting in adrenal insufficiency.
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| first_indexed | 2025-11-14T16:22:13Z |
| format | Article |
| id | iium-49649 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T16:22:13Z |
| publishDate | 2015 |
| publisher | Ministry of Health and Universiti Brunei Darussalem |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-496492017-11-30T02:35:31Z http://irep.iium.edu.my/49649/ Adrenal insufficiency resulting from Histoplasmosis infiltration in an immunocompetent patient Shahar, Mohammad Arif Ab Wahab, Norasyikin AbAziz, Aini Omar , Ahmad Marzuki Mohd Rusly, Noor Ashikin Kamaruddin, Nor Azmi R Medicine (General) RC Internal medicine Histoplasmosis usually affects immunocompromised patients. Histoplasmosis infiltration to the adrenal in an immunocompetent host is rare, more so those who presented with adrenal insufficiency. We report a case of 54-year-old previously fit and healthy man who presented with chronic headache of two months duration that was associated with loss of appetite and weight-loss. He had hypotension, hyponatremia, relative hyperkalemia with morning cortisol of 160 nmol/L. Computed tomography of the adrenals showed bilateral enlarged adrenal glands and biopsy confirmed histoplasmosis infiltration. Treatment successfully ameliorate symptoms of hypocortisolism. This case illustrates that immunocompetent patient is still susceptible to adrenal histoplasmosis resulting in adrenal insufficiency. Ministry of Health and Universiti Brunei Darussalem 2015-10 Article PeerReviewed application/pdf en http://irep.iium.edu.my/49649/1/Bimj2015115261.pdf Shahar, Mohammad Arif and Ab Wahab, Norasyikin and AbAziz, Aini and Omar , Ahmad Marzuki and Mohd Rusly, Noor Ashikin and Kamaruddin, Nor Azmi (2015) Adrenal insufficiency resulting from Histoplasmosis infiltration in an immunocompetent patient. Brunei International Medical Journal, 11 (5). pp. 261-264. ISSN 2079-3146 (O), 1560-5876 (P) http://www.bimjonline.com/Current%20Issues/currentissues.htm |
| spellingShingle | R Medicine (General) RC Internal medicine Shahar, Mohammad Arif Ab Wahab, Norasyikin AbAziz, Aini Omar , Ahmad Marzuki Mohd Rusly, Noor Ashikin Kamaruddin, Nor Azmi Adrenal insufficiency resulting from Histoplasmosis infiltration in an immunocompetent patient |
| title | Adrenal insufficiency resulting from Histoplasmosis infiltration in an immunocompetent patient |
| title_full | Adrenal insufficiency resulting from Histoplasmosis infiltration in an immunocompetent patient |
| title_fullStr | Adrenal insufficiency resulting from Histoplasmosis infiltration in an immunocompetent patient |
| title_full_unstemmed | Adrenal insufficiency resulting from Histoplasmosis infiltration in an immunocompetent patient |
| title_short | Adrenal insufficiency resulting from Histoplasmosis infiltration in an immunocompetent patient |
| title_sort | adrenal insufficiency resulting from histoplasmosis infiltration in an immunocompetent patient |
| topic | R Medicine (General) RC Internal medicine |
| url | http://irep.iium.edu.my/49649/ http://irep.iium.edu.my/49649/ http://irep.iium.edu.my/49649/1/Bimj2015115261.pdf |