A descriptive study of blood films of patients serologically positive for dengue in Hospital Tengku Ampuan Afzan, Kuantan

Introduction: Dengue is one of the commonest infections in Malaysia and it is a notifiable disease. Even though the diagnosis of classical dengue fever and dengue haemorrhagic fever can be recognized clinically, the diagnosis remains a challenge in areas where it could not be differentiated with oth...

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Main Authors: Ismail, Rusmawati, H, Asma Hanim, Muhammad, Siti Aeshah @ Naznin, Mohd Shahid, Salman, A.Talib, Norlelawati
Format: Article
Language:English
Published: Faculty of Medicine, International Islamic University Malaysia 2010
Subjects:
Online Access:http://irep.iium.edu.my/4952/
http://irep.iium.edu.my/4952/1/Dengue_%2C2010.pdf
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author Ismail, Rusmawati
H, Asma Hanim
Muhammad, Siti Aeshah @ Naznin
Mohd Shahid, Salman
A.Talib, Norlelawati
author_facet Ismail, Rusmawati
H, Asma Hanim
Muhammad, Siti Aeshah @ Naznin
Mohd Shahid, Salman
A.Talib, Norlelawati
author_sort Ismail, Rusmawati
building IIUM Repository
collection Online Access
description Introduction: Dengue is one of the commonest infections in Malaysia and it is a notifiable disease. Even though the diagnosis of classical dengue fever and dengue haemorrhagic fever can be recognized clinically, the diagnosis remains a challenge in areas where it could not be differentiated with other febrile illnesses. The aim of this study was to focus on the specific and consistent morphological features observed in blood films of dengue infection. Materials and Methods: In all 400 cases of dengue infection serologically diagnosed in the Tengku Ampuan Afzan Hospital (HTAA) during May to October 2007, only a total of 27 cases had blood films examined, and thus were included in this study. These blood films were re-examined by two pathologists from HTAA. The full blood count parameters were also retrieved and studied. Results: We consistently found typical reactive lymphocytes [n= 23 (85%)] and thrombocytopenia [n=21, (77.8%)] in the cases. However, leucopenia was present only in 9 cases (33%). Conclusion: The presence of typical reactive lymphocyte is a consistent  nding in dengue fever and thus could have a significant role in supporting the diagnosis of dengue infection.
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spelling iium-49522022-04-07T01:44:31Z http://irep.iium.edu.my/4952/ A descriptive study of blood films of patients serologically positive for dengue in Hospital Tengku Ampuan Afzan, Kuantan Ismail, Rusmawati H, Asma Hanim Muhammad, Siti Aeshah @ Naznin Mohd Shahid, Salman A.Talib, Norlelawati RB Pathology Introduction: Dengue is one of the commonest infections in Malaysia and it is a notifiable disease. Even though the diagnosis of classical dengue fever and dengue haemorrhagic fever can be recognized clinically, the diagnosis remains a challenge in areas where it could not be differentiated with other febrile illnesses. The aim of this study was to focus on the specific and consistent morphological features observed in blood films of dengue infection. Materials and Methods: In all 400 cases of dengue infection serologically diagnosed in the Tengku Ampuan Afzan Hospital (HTAA) during May to October 2007, only a total of 27 cases had blood films examined, and thus were included in this study. These blood films were re-examined by two pathologists from HTAA. The full blood count parameters were also retrieved and studied. Results: We consistently found typical reactive lymphocytes [n= 23 (85%)] and thrombocytopenia [n=21, (77.8%)] in the cases. However, leucopenia was present only in 9 cases (33%). Conclusion: The presence of typical reactive lymphocyte is a consistent  nding in dengue fever and thus could have a significant role in supporting the diagnosis of dengue infection. Faculty of Medicine, International Islamic University Malaysia 2010 Article PeerReviewed application/pdf en http://irep.iium.edu.my/4952/1/Dengue_%2C2010.pdf Ismail, Rusmawati and H, Asma Hanim and Muhammad, Siti Aeshah @ Naznin and Mohd Shahid, Salman and A.Talib, Norlelawati (2010) A descriptive study of blood films of patients serologically positive for dengue in Hospital Tengku Ampuan Afzan, Kuantan. International Medical Journal Malaysia, 9 (2). pp. 35-37. ISSN 1823-4631 http://www.e-imj.com/
spellingShingle RB Pathology
Ismail, Rusmawati
H, Asma Hanim
Muhammad, Siti Aeshah @ Naznin
Mohd Shahid, Salman
A.Talib, Norlelawati
A descriptive study of blood films of patients serologically positive for dengue in Hospital Tengku Ampuan Afzan, Kuantan
title A descriptive study of blood films of patients serologically positive for dengue in Hospital Tengku Ampuan Afzan, Kuantan
title_full A descriptive study of blood films of patients serologically positive for dengue in Hospital Tengku Ampuan Afzan, Kuantan
title_fullStr A descriptive study of blood films of patients serologically positive for dengue in Hospital Tengku Ampuan Afzan, Kuantan
title_full_unstemmed A descriptive study of blood films of patients serologically positive for dengue in Hospital Tengku Ampuan Afzan, Kuantan
title_short A descriptive study of blood films of patients serologically positive for dengue in Hospital Tengku Ampuan Afzan, Kuantan
title_sort descriptive study of blood films of patients serologically positive for dengue in hospital tengku ampuan afzan, kuantan
topic RB Pathology
url http://irep.iium.edu.my/4952/
http://irep.iium.edu.my/4952/
http://irep.iium.edu.my/4952/1/Dengue_%2C2010.pdf