The chemopreventive effects of Nigella sativa extract and Thymoquinone in a paternal toxicity study

QR Code

The chemopreventive effects of Nigella sativa extract and Thymoquinone in a paternal toxicity study

Studies have reported that exposure to cyclophosphamide (CPA) for cancer treatment result in adverse reproductive consequences. Over-production of reactive oxygen species causes oxidative stress thus affecting the DNA in male germ cell thus induces sperm defects. Our goal is to assess the potential...

Full description

Bibliographic Details
Main Authors:	Abdul Samat, Nadia Hanis, Abdul Rahman, Suzanah, Ahmad, Nur Amalina
Format:	Proceeding Paper
Language:	English English
Published:	2015
Subjects:	RM Therapeutics. Pharmacology RM300 Drugs and their action
Online Access:	http://irep.iium.edu.my/49400/ http://irep.iium.edu.my/49400/10/49400-program%20book.pdf http://irep.iium.edu.my/49400/1/iCAST_Nadia_Suzanah_KAHS_PDF.pdf

Similar Items

The potential of Nigella Sativa and thymoquinone in salvaging the embryo from effects of toxic paternal exposure
by: Abdul Samat, Nadia Hanis, et al.
Published: (2016)

The potential of nigella sativa and thymoquinone in salvaging the embryo from effects of toxic paternal exposure
by: Abdul Samat, Nadia Hanis, et al.
Published: (2016)

Prophylactic effects of Nigella sativa extract and thymoquinone against cyclophosphamide-induced sperm head abnormalities and chromatin instability in mice
by: Abdul Rahman, Suzanah, et al.
Published: (2017)

Investigating the potential of Nigella Sativa and thymoquinone in salvaging the embryo from effects of toxic paternal exposure to cyclophosphamide
by: Abdul Rahman, Suzanah, et al.
Published: (2017)

Potential effects of Nigella sativa and thymoquinone on the foetal development of cyclophosphamide-treated male mice
by: Abdul Rahman, Suzanah, et al.
Published: (2016)

Activation of mouse oocytes and in vitro embryo enhancing potential of Nigella Sativa
by: Abdul Rahman, Suzanah, et al.
Published: (2015)

Investigating the potential of Nigella sativa and thymoquinone in salvaging the embryo from effects of toxic paternal exposure to cyclophosphamide
by: Abdul Rahman, Suzanah, et al.
Published: (2017)

Short-term effects of TAF 273 on oestrous cycle and reproductive hormones of normal rats
by: Ahmad, Nur Amalina, et al.
Published: (2015)

The effect of Nigella sativa extract on mouse oocyte activation
by: Abdul Rahman, Suzanah, et al.
Published: (2014)

Anti-cancer activities of Thymoquinone, constituents of Nigella sativa against oral cancer cell lines
by: Arief Ichwan, Solachuddin Jauhari, et al.
Published: (2010)

Apoptotic activities of thymoquinone, an active ingredient of black seed (nigella sativa), in cervical cancer cell lines
by: Arief Ichwan, Solachuddin Jauhari, et al.
Published: (2014)

Effects of Eurycoma longifolia standardized extract on Estradiol valerate-induced teratogenicity in female rats
by: Ahmad, Nur Amalina, et al.
Published: (2017)

Cytotoxicity of eurycoma longifolia root extract on female adenocarcinoma cell lines
by: Abdullah, 'Afif Raihan, et al.
Published: (2017)

In vitro evaluation of the effect of Pluchea indica extracts in promoting glucose consumption activity on a liver cell line
by: Suriyah, Wastuti Hidayati, et al.
Published: (2019)

In vitro study of antifungal activity of Entada spiralis Ridl. crude extract against dermatophytes of superficial skin disease
by: Harun, Aiza, et al.
Published: (2011)

Safety of the concurrent use of gabapentin and carbamazepine at moderate therapeutic doses
by: Al-Mahmood, Sinan, et al.
Published: (2017)

Arborinine from Glycosmis Pentaphylla (retz.) DC induces apoptosis through activation of Caspase-3/7 in human mammary gland Adenocarcinoma (MCF-7) cell line
by: Mohd Hussain, Nurlaili Najmie, et al.
Published: (2016)

Are physicians and clinical pharmacists aware and knowledgeable enough about inappropriate prescribing for elderly patients? Findings from Malaysia
by: Akkawi, Muhammad Eid, et al.
Published: (2018)

Non-neurotoxic activity of Malayan krait (Bungarus candidus) venom from Thailand
by: Charoenpitakchai, Mongkon, et al.
Published: (2018)

Studies on the red sea sponge Haliclona sp. for its chemical and cytotoxic properties
by: Al-Massarani, Shaza Mohamed, et al.
Published: (2016)

Patterns of initial opioid prescribing and its association with short and long-term use among opioid naïve patients: Experience from Malaysia
by: Zin, Che Suraya, et al.
Published: (2018)

Investigation of plasma concentrations of IL-6 and IL-10 in short and long-term opioid users with non-cancer pain
by: Zin, Che Suraya, et al.
Published: (2018)

Trends and patterns of analgesic utilization in Malaysia from 2010 to 2016: preference for tramadol
by: Zin, Che Suraya, et al.
Published: (2018)

Analysis of drug-related problems identified by future pharmacists in medical wards of tertiary hospitals in the state of Pahang, Malaysia
by: Elnaem, Mohamed Hassan Abdelaziz, et al.
Published: (2019)

Mitochondrial DNA quantity changes in leucocytes of cancer patients on cisplatin and 5-fluorouracil regimen
by: Khaing, Ei Phyo, et al.
Published: (2016)

Mechanisms of colorectal cancer cell growth and metastasis inhibition by Carp-1 functional mimetic-4
by: Ashour, Abdelkader Elbadawy Abbas, et al.
Published: (2019)

Research on nonsteroidal anti-inflammatory drugs in Malaysia: a bibliometric analysis
by: Zin, Che Suraya, et al.
Published: (2020)

Halal lifestyle and cancer
by: Amid, Azura
Published: (2011)

Preventive effect of Nigella Sativa oil against Hippocampal Pyramidal Cell loss induced by permanent bilateral common Carotid Artey Occlusion in rats
by: Ahmed, Qamar Uddin
Published: (2011)

Understanding the mechanism of action of denrophthoe pentandra leaves extract as anticancer agent
by: Sul'ain, Mohd Dasuki
Published: (2016)

Amalan dan penggunaan herba dalam perubatan tradisional melayu selepas bersalin di zon tengah, semenanjung Malaysia
by: Akhiar, Siti Khairul Bariyyah
Published: (2016)

Protective effect of black seed nigella sativa (l.) Against cyclophosphamide-induced toxicity on reproductive and acrosomal function in mice
by: Abdul Rahman, Suzanah, et al.
Published: (2013)

Thymoquinone, an active ingredient of Black Seed (Nigela saliva) induces distinct apoptotic pathways in C33A and Siha Cervical Cancer Cell Lines)
by: Ichwan, Solachuddin JA, et al.
Published: (2012)

Mnemonic effects of Fixed Oil of Black Cumin (Nigella sativa) seeds on aged rats with memory impairment
by: Azzubaidi, Marwan Saad, et al.
Published: (2011)

Antihypertensive and antihyperlipidemic activities of thymoquinone in l-name hypertensive rats
by: Azzubaidi, Marwan Saad, et al.
Published: (2015)

Proanthocyanidin-rich date seed extract protects against chemically induced hepatorenal toxicity
by: Ahmed, Atallah F., et al.
Published: (2015)

Hepatorenal protective effect of Antistax(®) against chemically-induced toxicity
by: Ahmed, Atallah F., et al.
Published: (2015)

Global metabolic analyses identify key differences in metabolite levels between polymyxin-susceptible and polymyxin-resistant Acinetobacter baumannii
by: Mahamad Maifiah, Mohd Hafidz, et al.
Published: (2016)

Untargeted metabolomics analysis reveals key pathways responsible for the synergistic killing of colistin and doripenem combination against Acinetobacter baumannii
by: Mahamad Maifiah, Mohd Hafidz, et al.
Published: (2017)

Genome-scale metabolic modeling of responses to polymyxins in Pseudomonas aeruginosa
by: Zhu, Yan, et al.
Published: (2018)