Activation of mouse oocytes and in vitro embryo enhancing potential of Nigella Sativa
Objective: Aim of the present study is to optimize the development of the mouse embryo with addition of different concentrations of Nigella sativa extract in the culture. Methods: In this study, three different concentrations of Nigella sativa supplementation were used to assist in the enhancement...
| Main Authors: | , , , |
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| Format: | Proceeding Paper |
| Language: | English |
| Published: |
2015
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/49392/ http://irep.iium.edu.my/49392/14/ICAMS%202015%20Programme%20_complete.pdf |
| _version_ | 1848783450788593664 |
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| author | Abdul Rahman, Suzanah Abdul Rahman, Mohd Rahimi Ashraf Abdul Samat, Nadia Hanis Basha, Sadak |
| author_facet | Abdul Rahman, Suzanah Abdul Rahman, Mohd Rahimi Ashraf Abdul Samat, Nadia Hanis Basha, Sadak |
| author_sort | Abdul Rahman, Suzanah |
| building | IIUM Repository |
| collection | Online Access |
| description | Objective: Aim of the present study is to optimize the development of the mouse embryo with addition of different concentrations of Nigella sativa extract in the culture.
Methods: In this study, three different concentrations of Nigella sativa supplementation were used to assist in the enhancement of embryo development. G-1 media was used as a control (Group I). Groups II, III and IV were modified with the addition of Nigella sativa at low dose (5%), moderate dose (10%) and high dose (15%) respectively.
Results: Results showed an increase in the number of oocytes that successfully developed into morula and blastocyst after supplementation with three different concentrations of Nigella sativa in the embryo medium.
Conclusions: The outcome of the study indicated that Nigella sativa supplementation at a moderate concentration may help in the optimization of mouse embryo culture leading to an increase in the number of morulas and blastocysts. |
| first_indexed | 2025-11-14T16:21:33Z |
| format | Proceeding Paper |
| id | iium-49392 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T16:21:33Z |
| publishDate | 2015 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-493922017-05-03T05:17:29Z http://irep.iium.edu.my/49392/ Activation of mouse oocytes and in vitro embryo enhancing potential of Nigella Sativa Abdul Rahman, Suzanah Abdul Rahman, Mohd Rahimi Ashraf Abdul Samat, Nadia Hanis Basha, Sadak RM300 Drugs and their action Objective: Aim of the present study is to optimize the development of the mouse embryo with addition of different concentrations of Nigella sativa extract in the culture. Methods: In this study, three different concentrations of Nigella sativa supplementation were used to assist in the enhancement of embryo development. G-1 media was used as a control (Group I). Groups II, III and IV were modified with the addition of Nigella sativa at low dose (5%), moderate dose (10%) and high dose (15%) respectively. Results: Results showed an increase in the number of oocytes that successfully developed into morula and blastocyst after supplementation with three different concentrations of Nigella sativa in the embryo medium. Conclusions: The outcome of the study indicated that Nigella sativa supplementation at a moderate concentration may help in the optimization of mouse embryo culture leading to an increase in the number of morulas and blastocysts. 2015 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/49392/14/ICAMS%202015%20Programme%20_complete.pdf Abdul Rahman, Suzanah and Abdul Rahman, Mohd Rahimi Ashraf and Abdul Samat, Nadia Hanis and Basha, Sadak (2015) Activation of mouse oocytes and in vitro embryo enhancing potential of Nigella Sativa. In: The 2nd International Conference on Advances in Medical Science (ICAMS), 14-16 April 2015, Concorde Hotel, Kuala Lumpur. (Unpublished) http://klconference.com/about-conference |
| spellingShingle | RM300 Drugs and their action Abdul Rahman, Suzanah Abdul Rahman, Mohd Rahimi Ashraf Abdul Samat, Nadia Hanis Basha, Sadak Activation of mouse oocytes and in vitro embryo enhancing potential of Nigella Sativa |
| title | Activation of mouse oocytes and in vitro embryo enhancing potential of Nigella Sativa |
| title_full | Activation of mouse oocytes and in vitro embryo enhancing potential of Nigella Sativa |
| title_fullStr | Activation of mouse oocytes and in vitro embryo enhancing potential of Nigella Sativa |
| title_full_unstemmed | Activation of mouse oocytes and in vitro embryo enhancing potential of Nigella Sativa |
| title_short | Activation of mouse oocytes and in vitro embryo enhancing potential of Nigella Sativa |
| title_sort | activation of mouse oocytes and in vitro embryo enhancing potential of nigella sativa |
| topic | RM300 Drugs and their action |
| url | http://irep.iium.edu.my/49392/ http://irep.iium.edu.my/49392/ http://irep.iium.edu.my/49392/14/ICAMS%202015%20Programme%20_complete.pdf |