Beta-Lactam Infusion in Severe Sepsis (BLISS): a prospective, two-centre, open-labelled randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis

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Beta-Lactam Infusion in Severe Sepsis (BLISS): a prospective, two-centre, open-labelled randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis

This study aims to determine if continuous infusion (CI) is associated with better clinical and pharmacokinetic/pharmacodynamic (PK/PD) outcomes compared to intermittent bolus (IB) dosing in critically ill patients with severe sepsis. This was a two-centre randomised controlled trial of CI versus I...

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Bibliographic Details
Main Authors:	Abdul Aziz, Mohd. Hafiz, Sulaiman, Helmi, Mat Nor, Mohd Basri, Rai, Vineya, Wong, K., Hasan, Mohd Shahnaz, Abd. Rahman, Nurul Azrin, Jamal, Janattul-Ain, Wallis, Steven C., Lipman, Jeffrey, Staatz, Christine E., Roberts, Jason A.
Format:	Article
Language:	English English
Published:	Springer Verlag 2016
Subjects:	QR Microbiology RM Therapeutics. Pharmacology RS Pharmacy and materia medica
Online Access:	http://irep.iium.edu.my/49261/ http://irep.iium.edu.my/49261/6/Abdul-Aziz%20et%20al.%202016.%20Intensive%20Care%20Medicine.pdf http://irep.iium.edu.my/49261/12/49261_Beta-Lactam%20Infusion_wos.pdf

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