Application of group-based QSAR and molecular docking in the design of insulin-like growth factor antagonists

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Application of group-based QSAR and molecular docking in the design of insulin-like growth factor antagonists

Purpose: To identify the structural requirements for designing a lead key for insulin-like growth factor (IGF-1R) inhibition using group-based quantitative structure activity relationship (GQSAR) and molecular docking. Methods: GQSAR method requires fragmentation of molecules. The molecules in the...

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Bibliographic Details
Main Authors:	Abdullahi, Abubakar Danjuma, Abdualkader, Abdualrahman Mohammed, Abdulsamat, Nadiahanis, Ingale, Kundan
Format:	Article
Language:	English English
Published:	Pharmacotherapy Group 2015
Subjects:	QD Chemistry RS Pharmacy and materia medica
Online Access:	http://irep.iium.edu.my/49051/ http://irep.iium.edu.my/49051/1/Application_of_Group-Based_QSAR_and_Molecular_Docking_in_the_Design_of_Insulin-Like_Growth_Factor_Antagonists.pdf http://irep.iium.edu.my/49051/4/49051_Application%20of%20group-based%20QSAR%20and%20molecular_SCOPUS.pdf

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