A hydrophobic barrier deep within the inner pore of the TWIK-1 K2P potassium channel

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A hydrophobic barrier deep within the inner pore of the TWIK-1 K2P potassium channel

Recent X-ray crystal structures of the two-pore domain (K2P) family of potassium channels have revealed a unique structural architecture at the point where the cytoplasmic bundle-crossing gate is found in most other tetrameric K+ channels. However, despite the apparently open nature of the inner por...

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Bibliographic Details
Main Authors:	Aryal, Prafulla, Abd Wahab, Firdaus, Bucci, Giovanna, Sansom, Mark, Stephen, Tucker
Format:	Article
Language:	English English
Published:	Nature Publishing Group 2014
Subjects:	Q Science (General) RM Therapeutics. Pharmacology
Online Access:	http://irep.iium.edu.my/47584/ http://irep.iium.edu.my/47584/1/47584.pdf http://irep.iium.edu.my/47584/4/47584_A%20hydrophobic%20barrier%20deep_SCOPUS.pdf

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