Cancer detection using an electronic nose: A preliminary study on detection and discrimination of cancerous cells
Lack of effective tools to diagnose lung cancer at an early stage has caused high mortality in cancer patients especially in lung cancer patients. Electronic nose (E-Nose) technology is believed to offer non-invasive, rapid and reliable analytic approach by measuring the odour released from can...
| Main Authors: | , , , , , , , , , , |
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| Format: | Proceeding Paper |
| Language: | English English |
| Published: |
2014
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/47328/ http://irep.iium.edu.my/47328/4/47328.pdf http://irep.iium.edu.my/47328/7/47328_Cancer%20detection%20using%20an%20electronic%20nose_Scopus.pdf |
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| author | Thriumani, Reena Zakaria, Ammar Jeffree, Amanina Iymia Hishamuddin, N.A. Omar, Mohammad Iqbal Adom, Abdul Hamid Shakaff, Ali Yeon Kamarudin, Latifah Munirah Yusuf, Nurlisa Hashim, Yumi Zuhanis Has-Yun Mohamed Helmy, Khaled |
| author_facet | Thriumani, Reena Zakaria, Ammar Jeffree, Amanina Iymia Hishamuddin, N.A. Omar, Mohammad Iqbal Adom, Abdul Hamid Shakaff, Ali Yeon Kamarudin, Latifah Munirah Yusuf, Nurlisa Hashim, Yumi Zuhanis Has-Yun Mohamed Helmy, Khaled |
| author_sort | Thriumani, Reena |
| building | IIUM Repository |
| collection | Online Access |
| description | Lack of effective tools to diagnose lung cancer at
an early stage has caused high mortality in cancer patients
especially in lung cancer patients. Electronic nose (E-Nose)
technology is believed to offer non-invasive, rapid and reliable
analytic approach by measuring the odour released from
cancer to assist medical diagnosis. In this work, using a
commercial E-nose (Cyranose-320), we aimed to detect the
volatile organic compounds (VOCs) emitted by different types
of cancerous cells. The lung cancer cell (A549) and breast
cancer cell (MCF-7) were used for this study. Both cells were
cultured using Dulbecco’s Modified Eagle’s Medium (DMEM)
with 10% of Fetal Bovine Serum (FBS) and incubated for three
days. The static headspace of cell cultures and blank medium
were directly sniffed by Cyranose-320. The preliminary results
from this study showed that, the E-nose is able to detect and
distinguish the presence of VOCs in cancerous cells with
accuracy of 100% using LDA. To this end, the VOCs emitted
from cancerous cells can potentially used as biomarker. |
| first_indexed | 2025-11-14T16:16:23Z |
| format | Proceeding Paper |
| id | iium-47328 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-14T16:16:23Z |
| publishDate | 2014 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-473282017-09-25T03:53:07Z http://irep.iium.edu.my/47328/ Cancer detection using an electronic nose: A preliminary study on detection and discrimination of cancerous cells Thriumani, Reena Zakaria, Ammar Jeffree, Amanina Iymia Hishamuddin, N.A. Omar, Mohammad Iqbal Adom, Abdul Hamid Shakaff, Ali Yeon Kamarudin, Latifah Munirah Yusuf, Nurlisa Hashim, Yumi Zuhanis Has-Yun Mohamed Helmy, Khaled Q Science (General) RC Internal medicine RC254 Neoplasms. Tumors. Oncology (including Cancer) TA213 Engineering machinery, tools, and implements Lack of effective tools to diagnose lung cancer at an early stage has caused high mortality in cancer patients especially in lung cancer patients. Electronic nose (E-Nose) technology is believed to offer non-invasive, rapid and reliable analytic approach by measuring the odour released from cancer to assist medical diagnosis. In this work, using a commercial E-nose (Cyranose-320), we aimed to detect the volatile organic compounds (VOCs) emitted by different types of cancerous cells. The lung cancer cell (A549) and breast cancer cell (MCF-7) were used for this study. Both cells were cultured using Dulbecco’s Modified Eagle’s Medium (DMEM) with 10% of Fetal Bovine Serum (FBS) and incubated for three days. The static headspace of cell cultures and blank medium were directly sniffed by Cyranose-320. The preliminary results from this study showed that, the E-nose is able to detect and distinguish the presence of VOCs in cancerous cells with accuracy of 100% using LDA. To this end, the VOCs emitted from cancerous cells can potentially used as biomarker. 2014-12-08 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/47328/4/47328.pdf application/pdf en http://irep.iium.edu.my/47328/7/47328_Cancer%20detection%20using%20an%20electronic%20nose_Scopus.pdf Thriumani, Reena and Zakaria, Ammar and Jeffree, Amanina Iymia and Hishamuddin, N.A. and Omar, Mohammad Iqbal and Adom, Abdul Hamid and Shakaff, Ali Yeon and Kamarudin, Latifah Munirah and Yusuf, Nurlisa and Hashim, Yumi Zuhanis Has-Yun and Mohamed Helmy, Khaled (2014) Cancer detection using an electronic nose: A preliminary study on detection and discrimination of cancerous cells. In: 2014 IEEE International Conference on Biomedical Engineering and Sciences, 8th-10th December 2014, Miri, Sarawak. http://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=7047609 |
| spellingShingle | Q Science (General) RC Internal medicine RC254 Neoplasms. Tumors. Oncology (including Cancer) TA213 Engineering machinery, tools, and implements Thriumani, Reena Zakaria, Ammar Jeffree, Amanina Iymia Hishamuddin, N.A. Omar, Mohammad Iqbal Adom, Abdul Hamid Shakaff, Ali Yeon Kamarudin, Latifah Munirah Yusuf, Nurlisa Hashim, Yumi Zuhanis Has-Yun Mohamed Helmy, Khaled Cancer detection using an electronic nose: A preliminary study on detection and discrimination of cancerous cells |
| title | Cancer detection using an electronic nose: A preliminary
study on detection and discrimination of cancerous cells |
| title_full | Cancer detection using an electronic nose: A preliminary
study on detection and discrimination of cancerous cells |
| title_fullStr | Cancer detection using an electronic nose: A preliminary
study on detection and discrimination of cancerous cells |
| title_full_unstemmed | Cancer detection using an electronic nose: A preliminary
study on detection and discrimination of cancerous cells |
| title_short | Cancer detection using an electronic nose: A preliminary
study on detection and discrimination of cancerous cells |
| title_sort | cancer detection using an electronic nose: a preliminary
study on detection and discrimination of cancerous cells |
| topic | Q Science (General) RC Internal medicine RC254 Neoplasms. Tumors. Oncology (including Cancer) TA213 Engineering machinery, tools, and implements |
| url | http://irep.iium.edu.my/47328/ http://irep.iium.edu.my/47328/ http://irep.iium.edu.my/47328/4/47328.pdf http://irep.iium.edu.my/47328/7/47328_Cancer%20detection%20using%20an%20electronic%20nose_Scopus.pdf |