Anti-cancer potential of agarwood distillate
Agarwood or Gaharu by definition is the resin impregnated heartwood that produces unique aromatic scent when burnt. Apart from religious rituals and perfumes, agarwood has also been used as traditional medicines leading to the interest of this study which is to screen for anti-cancer properties....
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| Format: | Article |
| Language: | English |
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Journal of Pure and Applied Microbiology
2014
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/47143/ http://irep.iium.edu.my/47143/1/Paper_-__Abbas_et_al_2014_%28JPAM%29.pdf |
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| author | Abbas, Phirdaous Hashim, Yumi Zuhanis Has-Yun Amid, Azura Mohd. Salleh, Hamzah Jamal, Parveen Jaswir, Irwandi |
| author_facet | Abbas, Phirdaous Hashim, Yumi Zuhanis Has-Yun Amid, Azura Mohd. Salleh, Hamzah Jamal, Parveen Jaswir, Irwandi |
| author_sort | Abbas, Phirdaous |
| building | IIUM Repository |
| collection | Online Access |
| description | Agarwood or Gaharu by definition is the resin impregnated heartwood that
produces unique aromatic scent when burnt. Apart from religious rituals and perfumes,
agarwood has also been used as traditional medicines leading to the interest of this study
which is to screen for anti-cancer properties. In this study, agarwood water distillate
(hydrosol) obtained from distillation of agarwood (resin) were screened against MCF-7
cells, which are commonly used as in vitro model for breast cancer and VERO cells (normal
cells). Distillate samples were collected, diluted and directly subjected to three anti-cancer
screening assays (cell attachment assay, cell viability assay and sulforhodamine B assay).
It was found that agarwood distillate possesses anti-cancer activity and exerts no significant
effects on normal cells. This warrants further investigation with potential development of
alternative remedy against cancer while adding more value to the agarwood industry. |
| first_indexed | 2025-11-14T16:15:53Z |
| format | Article |
| id | iium-47143 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T16:15:53Z |
| publishDate | 2014 |
| publisher | Journal of Pure and Applied Microbiology |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-471432021-07-23T02:17:41Z http://irep.iium.edu.my/47143/ Anti-cancer potential of agarwood distillate Abbas, Phirdaous Hashim, Yumi Zuhanis Has-Yun Amid, Azura Mohd. Salleh, Hamzah Jamal, Parveen Jaswir, Irwandi Q Science (General) Agarwood or Gaharu by definition is the resin impregnated heartwood that produces unique aromatic scent when burnt. Apart from religious rituals and perfumes, agarwood has also been used as traditional medicines leading to the interest of this study which is to screen for anti-cancer properties. In this study, agarwood water distillate (hydrosol) obtained from distillation of agarwood (resin) were screened against MCF-7 cells, which are commonly used as in vitro model for breast cancer and VERO cells (normal cells). Distillate samples were collected, diluted and directly subjected to three anti-cancer screening assays (cell attachment assay, cell viability assay and sulforhodamine B assay). It was found that agarwood distillate possesses anti-cancer activity and exerts no significant effects on normal cells. This warrants further investigation with potential development of alternative remedy against cancer while adding more value to the agarwood industry. Journal of Pure and Applied Microbiology 2014-05 Article PeerReviewed application/pdf en http://irep.iium.edu.my/47143/1/Paper_-__Abbas_et_al_2014_%28JPAM%29.pdf Abbas, Phirdaous and Hashim, Yumi Zuhanis Has-Yun and Amid, Azura and Mohd. Salleh, Hamzah and Jamal, Parveen and Jaswir, Irwandi (2014) Anti-cancer potential of agarwood distillate. Journal of Pure and Applied Microbiology, 8 (Sp. ed). pp. 871-874. ISSN 0973-7510 http://www.microbiologyjournal.org/jmabsread.php?snoid=1895&month=&year= |
| spellingShingle | Q Science (General) Abbas, Phirdaous Hashim, Yumi Zuhanis Has-Yun Amid, Azura Mohd. Salleh, Hamzah Jamal, Parveen Jaswir, Irwandi Anti-cancer potential of agarwood distillate |
| title | Anti-cancer potential of agarwood distillate |
| title_full | Anti-cancer potential of agarwood distillate |
| title_fullStr | Anti-cancer potential of agarwood distillate |
| title_full_unstemmed | Anti-cancer potential of agarwood distillate |
| title_short | Anti-cancer potential of agarwood distillate |
| title_sort | anti-cancer potential of agarwood distillate |
| topic | Q Science (General) |
| url | http://irep.iium.edu.my/47143/ http://irep.iium.edu.my/47143/ http://irep.iium.edu.my/47143/1/Paper_-__Abbas_et_al_2014_%28JPAM%29.pdf |