Improved Fischer esterification of substituted benzoic acid under sealed-vessel microwave condition
Ethyl-4-fluoro-3-nitro benzoate was synthesised in good yield under closed vessel conditions using a single-mode microwave. This simple method involved adding catalytic amounts of H2SO4 at specific intervals of time to overcome the problems associated with equilibrium. The method was first optimised...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Penerbit Universiti Sains Malaysia
2015
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| Online Access: | http://irep.iium.edu.my/46576/ http://irep.iium.edu.my/46576/1/Journal_of_Physical_Science%2C_Vol._26%282%29%2C_53%E2%80%9361%2C_2015.pdf |
| _version_ | 1848782993013866496 |
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| author | Abd Hamid, Shafida Hamzah, Nurasyikin Abdul Rahim, Aisyah Saad |
| author_facet | Abd Hamid, Shafida Hamzah, Nurasyikin Abdul Rahim, Aisyah Saad |
| author_sort | Abd Hamid, Shafida |
| building | IIUM Repository |
| collection | Online Access |
| description | Ethyl-4-fluoro-3-nitro benzoate was synthesised in good yield under closed vessel conditions using a single-mode microwave. This simple method involved adding catalytic amounts of H2SO4 at specific intervals of time to overcome the problems associated with equilibrium. The method was first optimised in terms of temperature, and
the effect of using various solvents on the ester product was also investigated. Primary alcohols produced the highest yield of the ester product compared to secondary alcohols, and tertiary alcohol resulted in the lowest. |
| first_indexed | 2025-11-14T16:14:16Z |
| format | Article |
| id | iium-46576 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T16:14:16Z |
| publishDate | 2015 |
| publisher | Penerbit Universiti Sains Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-465762021-08-06T10:56:12Z http://irep.iium.edu.my/46576/ Improved Fischer esterification of substituted benzoic acid under sealed-vessel microwave condition Abd Hamid, Shafida Hamzah, Nurasyikin Abdul Rahim, Aisyah Saad QD Chemistry Ethyl-4-fluoro-3-nitro benzoate was synthesised in good yield under closed vessel conditions using a single-mode microwave. This simple method involved adding catalytic amounts of H2SO4 at specific intervals of time to overcome the problems associated with equilibrium. The method was first optimised in terms of temperature, and the effect of using various solvents on the ester product was also investigated. Primary alcohols produced the highest yield of the ester product compared to secondary alcohols, and tertiary alcohol resulted in the lowest. Penerbit Universiti Sains Malaysia 2015 Article PeerReviewed application/pdf en http://irep.iium.edu.my/46576/1/Journal_of_Physical_Science%2C_Vol._26%282%29%2C_53%E2%80%9361%2C_2015.pdf Abd Hamid, Shafida and Hamzah, Nurasyikin and Abdul Rahim, Aisyah Saad (2015) Improved Fischer esterification of substituted benzoic acid under sealed-vessel microwave condition. Journal of Physical Science , 26 (2). pp. 53-61. ISSN 1675-3402 |
| spellingShingle | QD Chemistry Abd Hamid, Shafida Hamzah, Nurasyikin Abdul Rahim, Aisyah Saad Improved Fischer esterification of substituted benzoic acid under sealed-vessel microwave condition |
| title | Improved Fischer esterification of substituted benzoic acid under sealed-vessel microwave condition |
| title_full | Improved Fischer esterification of substituted benzoic acid under sealed-vessel microwave condition |
| title_fullStr | Improved Fischer esterification of substituted benzoic acid under sealed-vessel microwave condition |
| title_full_unstemmed | Improved Fischer esterification of substituted benzoic acid under sealed-vessel microwave condition |
| title_short | Improved Fischer esterification of substituted benzoic acid under sealed-vessel microwave condition |
| title_sort | improved fischer esterification of substituted benzoic acid under sealed-vessel microwave condition |
| topic | QD Chemistry |
| url | http://irep.iium.edu.my/46576/ http://irep.iium.edu.my/46576/1/Journal_of_Physical_Science%2C_Vol._26%282%29%2C_53%E2%80%9361%2C_2015.pdf |