Production of tilapia fish gelatin nanoparticles

Gelatin is a very versatile natural biopolymer. It has more advantages such as biocompatibility, low cost, and biodegradability. Due to these advantages led to its application in the synthesis nanoparticles for drug delivery during the last decade. However due to tendency of inter-particle aggregati...

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Main Authors: Ibrahim Ali, Noorbatcha, Jaswir, Irwandi, Al-Khatib, Ma'an Fahmi Rashid
Format: Proceeding Paper
Language:English
English
Published: 2015
Subjects:
Online Access:http://irep.iium.edu.my/46375/
http://irep.iium.edu.my/46375/1/Gelatin_NP_IRIIE_2015.pdf
http://irep.iium.edu.my/46375/4/List_of_submissions_IRIIE_2015.pdf
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author Ibrahim Ali, Noorbatcha
Jaswir, Irwandi
Al-Khatib, Ma'an Fahmi Rashid
author_facet Ibrahim Ali, Noorbatcha
Jaswir, Irwandi
Al-Khatib, Ma'an Fahmi Rashid
author_sort Ibrahim Ali, Noorbatcha
building IIUM Repository
collection Online Access
description Gelatin is a very versatile natural biopolymer. It has more advantages such as biocompatibility, low cost, and biodegradability. Due to these advantages led to its application in the synthesis nanoparticles for drug delivery during the last decade. However due to tendency of inter-particle aggregation, stability of nanoparticles remains a big challenge and transient to be easily captured and analyzed. Mainly, the current major raw materials for gelatin nanoparticles production are from mammalian skins and bones (either bovine or porcine). Based on ethical, religious and health reasons, the use of mammalian-derived gelatins in various food and non-food products are main issue that criticism by Muslim, Jews, vegetarians and other religious communities. In this regard, fish gelatin nanoparticle has been highlighted as a better alternative to mammalian gelatins nanoparticles. Tilapia fish gelatin fabricated into nanoparticles using two-step desolvation method which involved the use of glutaraldehyde as crosslinking agent. Zeta sizer nano, FT-IR and FESEM was used for nanoparticles characterization. Fish gelatin has been successfully produced, in a size range between 100 nm and 200 nm. According to the infrared spectra, molecular bond of fish gelatin were similar to molecular bond of fish gelatin nanoparticles. The success of this research will be contributed in producing of halal drug.
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format Proceeding Paper
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institution International Islamic University Malaysia
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language English
English
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publishDate 2015
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spelling iium-463752024-05-06T07:12:50Z http://irep.iium.edu.my/46375/ Production of tilapia fish gelatin nanoparticles Ibrahim Ali, Noorbatcha Jaswir, Irwandi Al-Khatib, Ma'an Fahmi Rashid TP248.13 Biotechnology Gelatin is a very versatile natural biopolymer. It has more advantages such as biocompatibility, low cost, and biodegradability. Due to these advantages led to its application in the synthesis nanoparticles for drug delivery during the last decade. However due to tendency of inter-particle aggregation, stability of nanoparticles remains a big challenge and transient to be easily captured and analyzed. Mainly, the current major raw materials for gelatin nanoparticles production are from mammalian skins and bones (either bovine or porcine). Based on ethical, religious and health reasons, the use of mammalian-derived gelatins in various food and non-food products are main issue that criticism by Muslim, Jews, vegetarians and other religious communities. In this regard, fish gelatin nanoparticle has been highlighted as a better alternative to mammalian gelatins nanoparticles. Tilapia fish gelatin fabricated into nanoparticles using two-step desolvation method which involved the use of glutaraldehyde as crosslinking agent. Zeta sizer nano, FT-IR and FESEM was used for nanoparticles characterization. Fish gelatin has been successfully produced, in a size range between 100 nm and 200 nm. According to the infrared spectra, molecular bond of fish gelatin were similar to molecular bond of fish gelatin nanoparticles. The success of this research will be contributed in producing of halal drug. 2015 Proceeding Paper NonPeerReviewed application/pdf en http://irep.iium.edu.my/46375/1/Gelatin_NP_IRIIE_2015.pdf application/pdf en http://irep.iium.edu.my/46375/4/List_of_submissions_IRIIE_2015.pdf Ibrahim Ali, Noorbatcha and Jaswir, Irwandi and Al-Khatib, Ma'an Fahmi Rashid (2015) Production of tilapia fish gelatin nanoparticles. In: International Research, Invention and Innovation Exhibition 2015, 29-30 September 2015, Cultural Activity Centre, IIUM.
spellingShingle TP248.13 Biotechnology
Ibrahim Ali, Noorbatcha
Jaswir, Irwandi
Al-Khatib, Ma'an Fahmi Rashid
Production of tilapia fish gelatin nanoparticles
title Production of tilapia fish gelatin nanoparticles
title_full Production of tilapia fish gelatin nanoparticles
title_fullStr Production of tilapia fish gelatin nanoparticles
title_full_unstemmed Production of tilapia fish gelatin nanoparticles
title_short Production of tilapia fish gelatin nanoparticles
title_sort production of tilapia fish gelatin nanoparticles
topic TP248.13 Biotechnology
url http://irep.iium.edu.my/46375/
http://irep.iium.edu.my/46375/1/Gelatin_NP_IRIIE_2015.pdf
http://irep.iium.edu.my/46375/4/List_of_submissions_IRIIE_2015.pdf