Quantitative evaluation of p16INK4a promoter methylation using pyrosequencing in de novo diffuse large B-cell lymphoma

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Quantitative evaluation of p16INK4a promoter methylation using pyrosequencing in de novo diffuse large B-cell lymphoma

The p16INK4a tumor suppressor gene can be inactivated by a variety of events including promoter hypermethylation. In diffuse large B-cell lymphoma (DLBCL), p16INK4a methylation has been associated with advanced disease stage and higher IPI. The prognostic impact of p16INK4a methylation in DLBCL rem...

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Bibliographic Details
Main Authors:	Zainuddin, Norafiza, Kanduri, Meena, Berglund, Mattias, Lindell, Monica, Amini, Rose-Marie, Roos, Göran, Sundström, Christer, Enblad , Gunilla, Rosenquist, Richard
Format:	Article
Language:	English
Published:	Pergamon 2011
Subjects:	RC254 Neoplasms. Tumors. Oncology (including Cancer)
Online Access:	http://irep.iium.edu.my/4588/ http://irep.iium.edu.my/4588/1/p16.pdf

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