Recent progress on the development of herbal medicine in Malaysia

Standardization of medicinal herbs is one of Malaysian government strategy to warranty the quality of these herbs. One novel approach in standardization of the medicinal herbs is metabolomics. Metabolomics is a comprehensive analysis of the whole metabolites in a sample. Identification of both ch...

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Main Author: Khatib, Alfi
Format: Proceeding Paper
Language:English
Published: 2015
Subjects:
Online Access:http://irep.iium.edu.my/45734/
http://irep.iium.edu.my/45734/1/abstract_and_certificate.pdf
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author Khatib, Alfi
author_facet Khatib, Alfi
author_sort Khatib, Alfi
building IIUM Repository
collection Online Access
description Standardization of medicinal herbs is one of Malaysian government strategy to warranty the quality of these herbs. One novel approach in standardization of the medicinal herbs is metabolomics. Metabolomics is a comprehensive analysis of the whole metabolites in a sample. Identification of both chemical and bio-markers can be performed by the instrumental analysis of both natural sources and animal biofluids and multivariate data analysis. All advanced instrumentation such as nuclear magnetic resonance spectroscopy, liquid chromatography-mass spectrometry, and gas chromatography-mass spectrometry are used in metabolomics. In this presentation, we give some examples of the application of metabolomics approach to identify the bioactive compounds in Orthosipon stamineus, Cosmos caudatus, and Melicope ptelefolia. This approach is also able to predict the bioactivity of these herbs. As a conclusion: metabolomics open the possibility to fasten the identification of novel bio- and chemical markers, and the validated calibration model can be used to predict the bioactivity of new set of herbal extract.
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institution International Islamic University Malaysia
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language English
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spelling iium-457342015-11-16T03:51:58Z http://irep.iium.edu.my/45734/ Recent progress on the development of herbal medicine in Malaysia Khatib, Alfi QD Chemistry Standardization of medicinal herbs is one of Malaysian government strategy to warranty the quality of these herbs. One novel approach in standardization of the medicinal herbs is metabolomics. Metabolomics is a comprehensive analysis of the whole metabolites in a sample. Identification of both chemical and bio-markers can be performed by the instrumental analysis of both natural sources and animal biofluids and multivariate data analysis. All advanced instrumentation such as nuclear magnetic resonance spectroscopy, liquid chromatography-mass spectrometry, and gas chromatography-mass spectrometry are used in metabolomics. In this presentation, we give some examples of the application of metabolomics approach to identify the bioactive compounds in Orthosipon stamineus, Cosmos caudatus, and Melicope ptelefolia. This approach is also able to predict the bioactivity of these herbs. As a conclusion: metabolomics open the possibility to fasten the identification of novel bio- and chemical markers, and the validated calibration model can be used to predict the bioactivity of new set of herbal extract. 2015-04-23 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/45734/1/abstract_and_certificate.pdf Khatib, Alfi (2015) Recent progress on the development of herbal medicine in Malaysia. In: International Seminar on 1st APTFI Congress, 23rd-25th April, 2015, Makssar, Indonesia. (Unpublished)
spellingShingle QD Chemistry
Khatib, Alfi
Recent progress on the development of herbal medicine in Malaysia
title Recent progress on the development of herbal medicine in Malaysia
title_full Recent progress on the development of herbal medicine in Malaysia
title_fullStr Recent progress on the development of herbal medicine in Malaysia
title_full_unstemmed Recent progress on the development of herbal medicine in Malaysia
title_short Recent progress on the development of herbal medicine in Malaysia
title_sort recent progress on the development of herbal medicine in malaysia
topic QD Chemistry
url http://irep.iium.edu.my/45734/
http://irep.iium.edu.my/45734/1/abstract_and_certificate.pdf