Phosphoglycerate mutase from Trypanosoma brucei is hyperactivated by cobalt in vitro, but not in vivo

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Phosphoglycerate mutase from Trypanosoma brucei is hyperactivated by cobalt in vitro, but not in vivo

Production of ATP by the glycolytic pathway in the mammalian pathogenic stage of protists from the genus Trypanosoma is required for the survival of the parasites. Cofactor-independent phosphoglycerate mutase (iPGAM) is particularly attractive as a drug target because it shows no similarity to the...

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Bibliographic Details
Main Author:	Ahmad Fuad, Fazia Adyani
Format:	Article
Language:	English
Published:	Royal Society of Chemistry 2011
Subjects:	Q Science (General)
Online Access:	http://irep.iium.edu.my/45464/ http://irep.iium.edu.my/45464/1/%2BFuad_et_al._2011.pdf

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