Human topoisomerase II alpha as a prognostic biomarker in cancer chemotherapy

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Human topoisomerase II alpha as a prognostic biomarker in cancer chemotherapy

Topoisomerases are nuclear enzymes that regulate topology of DNA by facilitating the temporary cleavage and ligation cycle of DNA. Among all forms of topoisomerases, TOP-IIA is extensively associated with cell proliferation and therefore is an important therapeutic target in diseases that involved c...

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Bibliographic Details
Main Authors:	Ali, Yousaf, Abd Hamid, Shafida
Format:	Article
Language:	English English
Published:	Springer 2016
Subjects:	QD Chemistry RM Therapeutics. Pharmacology
Online Access:	http://irep.iium.edu.my/45324/ http://irep.iium.edu.my/45324/1/45324.pdf http://irep.iium.edu.my/45324/4/45324_Human%20topoisomerase%20II%20alpha%20as%20a%20prognostic%20biomarker%20in%20cancer%20chemotherapy_SCOPUS.pdf

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