The anti-cancer effect of Ant-44 (Spermidine-Anthracene Conjugate) via Ornithine decarboxylase activity in K562 cells
Background Many tumors undergo dysregulation of polyamine homeostasis and up-regulation of ornithine decarboxylase (ODC) activity, which can promote carcinogenesis. The polyamine conjugate has shown promising chemopreventive activity against a range of human tumor cell types, but little is known ab...
| Main Authors: | Abdul Ghani, Radiah, Phanstiel, Otto, Wallace, Heather M. |
|---|---|
| Format: | Proceeding Paper |
| Language: | English |
| Published: |
2015
|
| Subjects: | |
| Online Access: | http://irep.iium.edu.my/44493/ http://irep.iium.edu.my/44493/1/44493.pdf |
Similar Items
Ant 4,4, a polyamine-anthracene conjugate, induces cell death
and recovery in human promyelogenous leukemia cells (HL-60)
by: Rui, Traquete, et al.
Published: (2013)
by: Rui, Traquete, et al.
Published: (2013)
Ornithine decarboxylase gene expression in human lung carcinoma cells, A549 treated with pomegranate juice
by: Abdul Ghani, Radiah, et al.
Published: (2015)
by: Abdul Ghani, Radiah, et al.
Published: (2015)
A putrescine–anthracene conjugate : a paradigm for selective drug delivery
by: Palmer, Andrew, et al.
Published: (2009)
by: Palmer, Andrew, et al.
Published: (2009)
Anthracene polyamine conjugates induce apoptosis in human leukaemic cells
by: Abdul Ghani, Radiah, et al.
Published: (2011)
by: Abdul Ghani, Radiah, et al.
Published: (2011)
Use of polyamine transport system by polyamine anthracene conjugates in human leukaemic cells
by: Abdul Ghani, Radiah, et al.
Published: (2014)
by: Abdul Ghani, Radiah, et al.
Published: (2014)
Spermidine/spermine N1-acetyltransferase gene expression in A549 cells treated with pomegranate juice
by: Nik Abdul Malek, Nik Nurasyikin, et al.
Published: (2015)
by: Nik Abdul Malek, Nik Nurasyikin, et al.
Published: (2015)
Ornithine decarboxylase gene expression in human lung adenocarcinoma cell (A549) treated with pomegranate juice
by: Abdul Ghani, Radiah, et al.
Published: (2015)
by: Abdul Ghani, Radiah, et al.
Published: (2015)
The cytotoxicity effect of ant-444 in human chronic myeloid leukaemia cells (K 562)
by: Khalid, Nor Bahijah, et al.
Published: (2013)
by: Khalid, Nor Bahijah, et al.
Published: (2013)
Synthesis and characterization of spermidine containing sulphur
by: Sahabudin, Adzly Hairee, et al.
Published: (2016)
by: Sahabudin, Adzly Hairee, et al.
Published: (2016)
Polyamine sulfur conjugates: a paradigmn for selective drug delivery to cancer cells via polyamine transport system
by: Abdul Ghani, Radiah, et al.
Published: (2018)
by: Abdul Ghani, Radiah, et al.
Published: (2018)
Structural changes and the differential expression of osteoprotegerin (OPG) and receptor activator of nuclear factor kB ligand (RANKL) in subchondral bone during the development of osteoarthritis
by: AKMAN, AKMA AZMIERA, et al.
Published: (2018)
by: AKMAN, AKMA AZMIERA, et al.
Published: (2018)
A retrospective study of CD44 immunohistochemical expression in recurrent breast cancer / Gan Soon Ching
by: Gan , Soon Ching
Published: (2017)
by: Gan , Soon Ching
Published: (2017)
The polyamine transport system: A means of selective delivery of potentially toxic agents to cancer cells?
by: Abdul Ghani, Radiah, et al.
Published: (2009)
by: Abdul Ghani, Radiah, et al.
Published: (2009)
The effects of Ficus auriculata (fig) on cell cycle profile and apoptosis activity of Human lung adenocarcinoma cells, A549
by: Jamil, Elyna Fatini, et al.
Published: (2016)
by: Jamil, Elyna Fatini, et al.
Published: (2016)
The role of polyamines as a chemopreventive agent in selected prophetic fruits against human lung adenocarcinoma cell line, A549
by: Abdul Ghani, Radiah, et al.
Published: (2018)
by: Abdul Ghani, Radiah, et al.
Published: (2018)
Chemopreventive effect of Punica granatum in human lung carcinoma A549 cells
by: Nik Abdul Malek, Nik Nurasyikin, et al.
Published: (2014)
by: Nik Abdul Malek, Nik Nurasyikin, et al.
Published: (2014)
The growth inhibitory effect of Henna (L.inermis) Aqueous extract in human lung cancer cells, A549
by: Abdul Ghani, Radiah, et al.
Published: (2014)
by: Abdul Ghani, Radiah, et al.
Published: (2014)
Chemopreventive effect of punica granatum on human lung
carcinoma A549 cells
by: Abdul Ghani, Radiah, et al.
Published: (2014)
by: Abdul Ghani, Radiah, et al.
Published: (2014)
Study on cancer prevention strategy by Punica granatum: the role of polyamines in regulating cell cycle and cell death in human lung carcinoma A549 cells
by: Nik Abdul Malek, Nik Nurasyikin, et al.
Published: (2016)
by: Nik Abdul Malek, Nik Nurasyikin, et al.
Published: (2016)
Polyamines deficient diet is a complementary strategy in fighting cancer: analysis on selected medicinal fruits
by: Abdul Ghani, Radiah, et al.
Published: (2019)
by: Abdul Ghani, Radiah, et al.
Published: (2019)
Piper sarmentosum induced apoptosis via mitochondrial pathway in human lung adenocarcinoma cells, A549
by: Sirajudeen, Azila, et al.
Published: (2016)
by: Sirajudeen, Azila, et al.
Published: (2016)
Knowledge and practice of galactogogues consumption among breastfeeding mothers in Pahang
by: Abdul Ghani, Radiah, et al.
Published: (2014)
by: Abdul Ghani, Radiah, et al.
Published: (2014)
A narrative review on pathology of amnesia and its relation with cessation (Rukhsah) of performing prayer (Solah)
by: Ariaff, Muhammad Ammar Adli, et al.
Published: (2017)
by: Ariaff, Muhammad Ammar Adli, et al.
Published: (2017)
Amnesia and its relation with concession (Rukhsah) on performing prayer (Solah)
by: Ariaff, Muhammad Ammar Adli, et al.
Published: (2018)
by: Ariaff, Muhammad Ammar Adli, et al.
Published: (2018)
Pomegranate juice induced cell cycle arrest and apoptosis through mitochondria pathway in human lung adenocarcinoma cells
by: Abdul Ghani, Radiah, et al.
Published: (2018)
by: Abdul Ghani, Radiah, et al.
Published: (2018)
Purification and characterization of glutamate decarboxylase from Aspergillus oryzae NSK
by: Lee, Audrey Ying Yeng
Published: (2014)
by: Lee, Audrey Ying Yeng
Published: (2014)
Antiproliferative activity of selected prophetic medicinal plants on human lung adenocarcinoma cells, A549
by: Abdul Ghani, Radiah, et al.
Published: (2015)
by: Abdul Ghani, Radiah, et al.
Published: (2015)
The influence of ante-natal phenytoin therapy on palatal fusion in rat embryo
by: Khaleel, Ruwaidah F., et al.
Published: (2014)
by: Khaleel, Ruwaidah F., et al.
Published: (2014)
Inherited anti-thrombin deficiency in a Malay-Malaysian family: a missense mutation at nucleotide g.13267C>A aka anti-thrombin Budapest 5 (p.Pro439Thr) of the SERPINC 1 gene
by: A.Talib, Norlelawati, et al.
Published: (2014)
by: A.Talib, Norlelawati, et al.
Published: (2014)
Neonatal-onset of ornithine transcarbamylase deficiency: a case of severe hyperammonaemia
by: Samsudin, Intan Nureslyna, et al.
Published: (2024)
by: Samsudin, Intan Nureslyna, et al.
Published: (2024)
Atherosclerosis in chronic organic arsenic (monosodium methylarsonate) exposure
by: Abdullah, Nor Zamzila, et al.
Published: (2015)
by: Abdullah, Nor Zamzila, et al.
Published: (2015)
Chronic Monosodium Methylarsonate (MSMA) exposure induces oxidation of Low Density Lipoprotein (LDL) and early atherosclerosis development
by: Adekunle, Ishola Afeez, et al.
Published: (2015)
by: Adekunle, Ishola Afeez, et al.
Published: (2015)
Antiatherosclerotic effect of Baccaurea angulate: an under-utilized fruit
by: Mikail, Maryam Abimbola, et al.
Published: (2014)
by: Mikail, Maryam Abimbola, et al.
Published: (2014)
Towards the bioproduction of methacrylic acid: a case study on the use of decarboxylases
by: Rossoni, Luca
Published: (2016)
by: Rossoni, Luca
Published: (2016)
Potential hypocholesterolemic and health benefitsof Baccaurea angulata fruit in hypercholesterolemic rabbits
by: Ahmed, Idris Adewale, et al.
Published: (2014)
by: Ahmed, Idris Adewale, et al.
Published: (2014)
Kesan sitotoksik sebatian difenilstanum (IV) alkilfenilditiokarbamat terhadap sel eritroleukemia, K562
by: Normah Awang,, et al.
Published: (2013)
by: Normah Awang,, et al.
Published: (2013)
Antitumor Effects of Madu Lebah Tualang on Human Leukemia Cell Line (K562)
by: Hassan, Rosline
Published: (2016)
by: Hassan, Rosline
Published: (2016)
Ficus auriculata (fig) extracts induced cell cycle profile changes and apoptosis through caspase-independent pathway in human LungAdenocarcinoma cell line, A549
by: Jamil, Elyna Fatini, et al.
Published: (2017)
by: Jamil, Elyna Fatini, et al.
Published: (2017)
The solutions for Semipositone (k,n-k) conjugate boundary value problems
by: Su, H., et al.
Published: (2015)
by: Su, H., et al.
Published: (2015)
Modular pathway rewiring of Saccharomyces cerevisiae enables high-level production of L-ornithine
by: Qin, J., et al.
Published: (2015)
by: Qin, J., et al.
Published: (2015)
Similar Items
-
Ant 4,4, a polyamine-anthracene conjugate, induces cell death
and recovery in human promyelogenous leukemia cells (HL-60)
by: Rui, Traquete, et al.
Published: (2013) -
Ornithine decarboxylase gene expression in human lung carcinoma cells, A549 treated with pomegranate juice
by: Abdul Ghani, Radiah, et al.
Published: (2015) -
A putrescine–anthracene conjugate : a paradigm for selective drug delivery
by: Palmer, Andrew, et al.
Published: (2009) -
Anthracene polyamine conjugates induce apoptosis in human leukaemic cells
by: Abdul Ghani, Radiah, et al.
Published: (2011) -
Use of polyamine transport system by polyamine anthracene conjugates in human leukaemic cells
by: Abdul Ghani, Radiah, et al.
Published: (2014)