Cytotoxic study of Linum usitatissimum and Salvia officinallis extracts on MCF-7 cell line (comparative study)
Salvia officinallis and linum usitatissimum are two natural extracts that have been studied before and resulted to have many beneficial values, the research experiment we have done was to investigate weather both of the extracts possess anticancer activities on breast cancer MCF-7 cell line. The MCF...
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| Format: | Proceeding Paper |
| Language: | English English |
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2015
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| Online Access: | http://irep.iium.edu.my/44448/ http://irep.iium.edu.my/44448/3/ICAST_PROGRAMME_BOOK_2015.pdf http://irep.iium.edu.my/44448/4/MED-MEP21..pdf |
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| author | Shaban, Sama Ichwan, Solachuddin J. A. Mustafa Al-Ahmad, Basma Ezzat Kashmola, Muhanad Ali Hamdon Mustafa, Nazih Shaban Taher, Muhammad |
| author_facet | Shaban, Sama Ichwan, Solachuddin J. A. Mustafa Al-Ahmad, Basma Ezzat Kashmola, Muhanad Ali Hamdon Mustafa, Nazih Shaban Taher, Muhammad |
| author_sort | Shaban, Sama |
| building | IIUM Repository |
| collection | Online Access |
| description | Salvia officinallis and linum usitatissimum are two natural extracts that have been studied before and resulted to have many beneficial values, the research experiment we have done was to investigate weather both of the extracts possess anticancer activities on breast cancer MCF-7 cell line. The MCF.7 cell line was maintained in Dulbecco’s Minimum Essential Medium (DMEM), supplemented with 10% fetal bovine serum (FBS) and 1% of penicillin and grown in 6 cm2 tissue culture dishes. A colorimetric MTT (3-(4,5-dimethythiazol-2-yl)-2,5-diphenyl tetrazolium bromide) assay was used to indicate the cell viability. The MTT test results have shown a slight gradual distraction of breast cancer cells by salvia officinallis oil and water extracts, for linum usitatissimum both oil and water extract have shown little to no growth constriction to MCF-7 breast cancer cells. In this experiment linum usitatissimum showed no cytotoxicity effects on MCF-7 in its both water and oil forms. As for Salvia officinallis there was a little growth constriction effects by its both water and oil extracts on MCF-7 cell line. |
| first_indexed | 2025-11-14T16:08:10Z |
| format | Proceeding Paper |
| id | iium-44448 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-14T16:08:10Z |
| publishDate | 2015 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-444482018-05-21T07:03:16Z http://irep.iium.edu.my/44448/ Cytotoxic study of Linum usitatissimum and Salvia officinallis extracts on MCF-7 cell line (comparative study) Shaban, Sama Ichwan, Solachuddin J. A. Mustafa Al-Ahmad, Basma Ezzat Kashmola, Muhanad Ali Hamdon Mustafa, Nazih Shaban Taher, Muhammad Q Science (General) RK Dentistry Salvia officinallis and linum usitatissimum are two natural extracts that have been studied before and resulted to have many beneficial values, the research experiment we have done was to investigate weather both of the extracts possess anticancer activities on breast cancer MCF-7 cell line. The MCF.7 cell line was maintained in Dulbecco’s Minimum Essential Medium (DMEM), supplemented with 10% fetal bovine serum (FBS) and 1% of penicillin and grown in 6 cm2 tissue culture dishes. A colorimetric MTT (3-(4,5-dimethythiazol-2-yl)-2,5-diphenyl tetrazolium bromide) assay was used to indicate the cell viability. The MTT test results have shown a slight gradual distraction of breast cancer cells by salvia officinallis oil and water extracts, for linum usitatissimum both oil and water extract have shown little to no growth constriction to MCF-7 breast cancer cells. In this experiment linum usitatissimum showed no cytotoxicity effects on MCF-7 in its both water and oil forms. As for Salvia officinallis there was a little growth constriction effects by its both water and oil extracts on MCF-7 cell line. 2015 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/44448/3/ICAST_PROGRAMME_BOOK_2015.pdf application/pdf en http://irep.iium.edu.my/44448/4/MED-MEP21..pdf Shaban, Sama and Ichwan, Solachuddin J. A. and Mustafa Al-Ahmad, Basma Ezzat and Kashmola, Muhanad Ali Hamdon and Mustafa, Nazih Shaban and Taher, Muhammad (2015) Cytotoxic study of Linum usitatissimum and Salvia officinallis extracts on MCF-7 cell line (comparative study). In: International Conference on Advancement in Science and Technology (iCAST 2015) - ‘Frontiers in Biotechnology’, 10-12 Aug 2015, Impiana Resort Cherating, Pahang, Malaysia. (Unpublished) http://www.iium.edu.my/icast/ |
| spellingShingle | Q Science (General) RK Dentistry Shaban, Sama Ichwan, Solachuddin J. A. Mustafa Al-Ahmad, Basma Ezzat Kashmola, Muhanad Ali Hamdon Mustafa, Nazih Shaban Taher, Muhammad Cytotoxic study of Linum usitatissimum and Salvia officinallis extracts on MCF-7 cell line (comparative study) |
| title | Cytotoxic study of Linum usitatissimum and Salvia officinallis extracts on MCF-7 cell line (comparative study)
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| title_full | Cytotoxic study of Linum usitatissimum and Salvia officinallis extracts on MCF-7 cell line (comparative study)
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| title_fullStr | Cytotoxic study of Linum usitatissimum and Salvia officinallis extracts on MCF-7 cell line (comparative study)
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| title_full_unstemmed | Cytotoxic study of Linum usitatissimum and Salvia officinallis extracts on MCF-7 cell line (comparative study)
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| title_short | Cytotoxic study of Linum usitatissimum and Salvia officinallis extracts on MCF-7 cell line (comparative study)
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| title_sort | cytotoxic study of linum usitatissimum and salvia officinallis extracts on mcf-7 cell line (comparative study) |
| topic | Q Science (General) RK Dentistry |
| url | http://irep.iium.edu.my/44448/ http://irep.iium.edu.my/44448/ http://irep.iium.edu.my/44448/3/ICAST_PROGRAMME_BOOK_2015.pdf http://irep.iium.edu.my/44448/4/MED-MEP21..pdf |