Rice husk ash silica as a potential drug carrier

Rice husk is a by-product from rice mills that are often regarded as an agricultural waste and practically has no commercial value. However, rice husk ash (RHA) obtained from the calcination of rice husk at elevated temperature offers a greener, safer and cheaper source of silica precursor. Currentl...

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Main Authors: Muhammad Shuib, Nur Azfa, Darnis, Deny Susanti, Mohamed Iqbal, Mohammad Anwar, Miskam, Mazidatulakmam
Format: Proceeding Paper
Language:English
Published: 2015
Subjects:
Online Access:http://irep.iium.edu.my/44395/
http://irep.iium.edu.my/44395/8/Nurazfa.pdf
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author Muhammad Shuib, Nur Azfa
Darnis, Deny Susanti
Mohamed Iqbal, Mohammad Anwar
Miskam, Mazidatulakmam
author_facet Muhammad Shuib, Nur Azfa
Darnis, Deny Susanti
Mohamed Iqbal, Mohammad Anwar
Miskam, Mazidatulakmam
author_sort Muhammad Shuib, Nur Azfa
building IIUM Repository
collection Online Access
description Rice husk is a by-product from rice mills that are often regarded as an agricultural waste and practically has no commercial value. However, rice husk ash (RHA) obtained from the calcination of rice husk at elevated temperature offers a greener, safer and cheaper source of silica precursor. Currently used silica precursor such as tetraethyl ortosilicate (TEOS) and sodium silicate are relative expensive and dangerous to human and environmental. RHA has been widely used as a silica support in heterogeneous catalysis but its capability as a drug carrier has not been explored. Thus, in this study we intended to investigate the properties of RHA-silica prepared via sol-gel as a potential drug carrier. The BET surface analysis measured the surface area to be 589 m2/g and the pore diameter as 5.1 nm. Based on the pore diameter, the RHA-silica is classified as mesoporous. The X-ray powder diffraction (XRD) showed that the RHA-silica is in amorphous form. The Fourier Transform Infrared Spectroscopy did not detect the presence of any organic moieties that are not related to silica which indicated the RHA-silica obtained is a pure silica. Based on these preliminary results, it can be said that the RHA-silica has potential to be used as a drug carrier.
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format Proceeding Paper
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institution International Islamic University Malaysia
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language English
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publishDate 2015
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spelling iium-443952015-11-16T03:53:12Z http://irep.iium.edu.my/44395/ Rice husk ash silica as a potential drug carrier Muhammad Shuib, Nur Azfa Darnis, Deny Susanti Mohamed Iqbal, Mohammad Anwar Miskam, Mazidatulakmam QD Chemistry Rice husk is a by-product from rice mills that are often regarded as an agricultural waste and practically has no commercial value. However, rice husk ash (RHA) obtained from the calcination of rice husk at elevated temperature offers a greener, safer and cheaper source of silica precursor. Currently used silica precursor such as tetraethyl ortosilicate (TEOS) and sodium silicate are relative expensive and dangerous to human and environmental. RHA has been widely used as a silica support in heterogeneous catalysis but its capability as a drug carrier has not been explored. Thus, in this study we intended to investigate the properties of RHA-silica prepared via sol-gel as a potential drug carrier. The BET surface analysis measured the surface area to be 589 m2/g and the pore diameter as 5.1 nm. Based on the pore diameter, the RHA-silica is classified as mesoporous. The X-ray powder diffraction (XRD) showed that the RHA-silica is in amorphous form. The Fourier Transform Infrared Spectroscopy did not detect the presence of any organic moieties that are not related to silica which indicated the RHA-silica obtained is a pure silica. Based on these preliminary results, it can be said that the RHA-silica has potential to be used as a drug carrier. 2015 Proceeding Paper NonPeerReviewed application/pdf en http://irep.iium.edu.my/44395/8/Nurazfa.pdf Muhammad Shuib, Nur Azfa and Darnis, Deny Susanti and Mohamed Iqbal, Mohammad Anwar and Miskam, Mazidatulakmam (2015) Rice husk ash silica as a potential drug carrier. In: International Conference on Advancement in Science and Technology (iCAST 2015) - ‘Frontiers in Biotechnology’, 10-12 August 2015, Impiana Resort Cherating, Pahang, Malaysia. (Unpublished) http://www.iium.edu.my/icast
spellingShingle QD Chemistry
Muhammad Shuib, Nur Azfa
Darnis, Deny Susanti
Mohamed Iqbal, Mohammad Anwar
Miskam, Mazidatulakmam
Rice husk ash silica as a potential drug carrier
title Rice husk ash silica as a potential drug carrier
title_full Rice husk ash silica as a potential drug carrier
title_fullStr Rice husk ash silica as a potential drug carrier
title_full_unstemmed Rice husk ash silica as a potential drug carrier
title_short Rice husk ash silica as a potential drug carrier
title_sort rice husk ash silica as a potential drug carrier
topic QD Chemistry
url http://irep.iium.edu.my/44395/
http://irep.iium.edu.my/44395/
http://irep.iium.edu.my/44395/8/Nurazfa.pdf