Isolation of secondary metabolites from quercus infectoria galls and their antimicrobial activity
The evolution of resistant microorganism towards available antibiotics has gain interest among scientists to search for more effective antimicrobial compounds. Plant is believe to have antimicrobial properties as the extract is used in food industry, pharmaceuticals and alternative medicine. The aim...
| Main Authors: | , , , |
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| Format: | Proceeding Paper |
| Language: | English |
| Published: |
2015
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/44394/ http://irep.iium.edu.my/44394/6/fatimatulakmal.pdf |
| _version_ | 1848782599732854784 |
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| author | Sulaiman, Fatimatul Akma Darnis, Deny Susanti Mohamed Iqbal, Mohammad Anwar Miskam, Mazidatulakmam Akmam |
| author_facet | Sulaiman, Fatimatul Akma Darnis, Deny Susanti Mohamed Iqbal, Mohammad Anwar Miskam, Mazidatulakmam Akmam |
| author_sort | Sulaiman, Fatimatul Akma |
| building | IIUM Repository |
| collection | Online Access |
| description | The evolution of resistant microorganism towards available antibiotics has gain interest among scientists to search for more effective antimicrobial compounds. Plant is believe to have antimicrobial properties as the extract is used in food industry, pharmaceuticals and alternative medicine. The aims of this study are to isolate secondary metabolites from Q. infectoria galls and to elucidate structure of the isolated compound using spectroscopic techniques and determination of antimicrobial activity. The galls were extracted with organic solvent using soxhlet apparatus and fractionated using chromatographic techniques. The isolated compounds were characterized using spectroscopic techniques such as UV spectrophotometer, Fourier Transform Infrared Spectroscopy (FTIR), Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (MS). The antimicrobial activities are determined using disc diffusion method, determination of MIC, MBC, MFC and synergistic effect. The disc diffusion test against Staphylococcus aureus showed zone of inhibition 7 mm (n-hexane extract) and 9 mm (methanol extract). Meanwhile, dichloromethane extract showed no inhibition against S. aureus. It is expected that the isolated compound have antimicrobial properties and synergistic effect in combination with standard antibiotic. |
| first_indexed | 2025-11-14T16:08:01Z |
| format | Proceeding Paper |
| id | iium-44394 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T16:08:01Z |
| publishDate | 2015 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-443942018-05-22T03:44:25Z http://irep.iium.edu.my/44394/ Isolation of secondary metabolites from quercus infectoria galls and their antimicrobial activity Sulaiman, Fatimatul Akma Darnis, Deny Susanti Mohamed Iqbal, Mohammad Anwar Miskam, Mazidatulakmam Akmam QD Chemistry The evolution of resistant microorganism towards available antibiotics has gain interest among scientists to search for more effective antimicrobial compounds. Plant is believe to have antimicrobial properties as the extract is used in food industry, pharmaceuticals and alternative medicine. The aims of this study are to isolate secondary metabolites from Q. infectoria galls and to elucidate structure of the isolated compound using spectroscopic techniques and determination of antimicrobial activity. The galls were extracted with organic solvent using soxhlet apparatus and fractionated using chromatographic techniques. The isolated compounds were characterized using spectroscopic techniques such as UV spectrophotometer, Fourier Transform Infrared Spectroscopy (FTIR), Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (MS). The antimicrobial activities are determined using disc diffusion method, determination of MIC, MBC, MFC and synergistic effect. The disc diffusion test against Staphylococcus aureus showed zone of inhibition 7 mm (n-hexane extract) and 9 mm (methanol extract). Meanwhile, dichloromethane extract showed no inhibition against S. aureus. It is expected that the isolated compound have antimicrobial properties and synergistic effect in combination with standard antibiotic. 2015 Proceeding Paper NonPeerReviewed application/pdf en http://irep.iium.edu.my/44394/6/fatimatulakmal.pdf Sulaiman, Fatimatul Akma and Darnis, Deny Susanti and Mohamed Iqbal, Mohammad Anwar and Miskam, Mazidatulakmam Akmam (2015) Isolation of secondary metabolites from quercus infectoria galls and their antimicrobial activity. In: 5th International Conference on Advancement in Science and Technology (iCAST 2015), 10-12 August 2015, Impiana Resort Cherating. (Unpublished) http://www.iium.edu.my/icast |
| spellingShingle | QD Chemistry Sulaiman, Fatimatul Akma Darnis, Deny Susanti Mohamed Iqbal, Mohammad Anwar Miskam, Mazidatulakmam Akmam Isolation of secondary metabolites from quercus infectoria galls and their antimicrobial activity |
| title | Isolation of secondary metabolites from quercus infectoria galls and their antimicrobial activity |
| title_full | Isolation of secondary metabolites from quercus infectoria galls and their antimicrobial activity |
| title_fullStr | Isolation of secondary metabolites from quercus infectoria galls and their antimicrobial activity |
| title_full_unstemmed | Isolation of secondary metabolites from quercus infectoria galls and their antimicrobial activity |
| title_short | Isolation of secondary metabolites from quercus infectoria galls and their antimicrobial activity |
| title_sort | isolation of secondary metabolites from quercus infectoria galls and their antimicrobial activity |
| topic | QD Chemistry |
| url | http://irep.iium.edu.my/44394/ http://irep.iium.edu.my/44394/ http://irep.iium.edu.my/44394/6/fatimatulakmal.pdf |