The mode of antimicrobial action of Cinnamomum burmannii’s essential oil & cinnamaldehyde
The incidence of antibiotic resistance and its side effect have urged scientist to search for new antimicrobial substances. Cinnamons are rich in essential oils which mainly consist of cinnamaldehyde as its bioactive compounds. The present study was designed to postulate the mode of antimicrobial ac...
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| Format: | Proceeding Paper |
| Language: | English |
| Published: |
2015
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| Online Access: | http://irep.iium.edu.my/44303/ http://irep.iium.edu.my/44303/1/44303.pdf |
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| author | Darnis, Deny Susanti Awang, Anis Fadhlina Izyani Bakhtiar, M. Taher |
| author_facet | Darnis, Deny Susanti Awang, Anis Fadhlina Izyani Bakhtiar, M. Taher |
| author_sort | Darnis, Deny Susanti |
| building | IIUM Repository |
| collection | Online Access |
| description | The incidence of antibiotic resistance and its side effect have urged scientist to search for new antimicrobial substances. Cinnamons are rich in essential oils which mainly consist of cinnamaldehyde as its bioactive compounds. The present study was designed to postulate the mode of antimicrobial actions of both essential oil and cinnamaldehyde against E. coli, S. aureus and C. albicans. The essential oil was extracted by steam distillation. Column chromatography was carried out in order to isolate cinnamaldehyde from the essential oil. Spectroscopic technique was used to characterize the isolated compound, cinnamaldehyde. There were four modes of action tested which included time-killing assay, salt tolerance assay, crystal violet assay and leakage of cellular metabolites. All of the tests were done in triplicate. The antimicrobial effect on the cell membrane was dose-dependent whereby stronger antimicrobial action was observed by cinnamaldehyde at concentration equal to 4×MIC (1.33 mg/mL) as compared to the essential oil. The potential of cinnamaldehyde as a potent antimicrobial compound of the cinnamon essential oil was discovered and proven to act on the cell membrane of microorganisms tested particularly against C. albicans. |
| first_indexed | 2025-11-14T16:07:49Z |
| format | Proceeding Paper |
| id | iium-44303 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T16:07:49Z |
| publishDate | 2015 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-443032022-11-08T05:11:23Z http://irep.iium.edu.my/44303/ The mode of antimicrobial action of Cinnamomum burmannii’s essential oil & cinnamaldehyde Darnis, Deny Susanti Awang, Anis Fadhlina Izyani Bakhtiar, M. Taher QD Chemistry The incidence of antibiotic resistance and its side effect have urged scientist to search for new antimicrobial substances. Cinnamons are rich in essential oils which mainly consist of cinnamaldehyde as its bioactive compounds. The present study was designed to postulate the mode of antimicrobial actions of both essential oil and cinnamaldehyde against E. coli, S. aureus and C. albicans. The essential oil was extracted by steam distillation. Column chromatography was carried out in order to isolate cinnamaldehyde from the essential oil. Spectroscopic technique was used to characterize the isolated compound, cinnamaldehyde. There were four modes of action tested which included time-killing assay, salt tolerance assay, crystal violet assay and leakage of cellular metabolites. All of the tests were done in triplicate. The antimicrobial effect on the cell membrane was dose-dependent whereby stronger antimicrobial action was observed by cinnamaldehyde at concentration equal to 4×MIC (1.33 mg/mL) as compared to the essential oil. The potential of cinnamaldehyde as a potent antimicrobial compound of the cinnamon essential oil was discovered and proven to act on the cell membrane of microorganisms tested particularly against C. albicans. 2015-08 Proceeding Paper NonPeerReviewed application/pdf en http://irep.iium.edu.my/44303/1/44303.pdf Darnis, Deny Susanti and Awang, Anis Fadhlina Izyani and Bakhtiar, M. Taher (2015) The mode of antimicrobial action of Cinnamomum burmannii’s essential oil & cinnamaldehyde. In: 5th International Conference on Advancement in Science and Technology (iCAST 2015), 10th-12th August 2015, Impiana Resort Cherating, Kuantan, Pahang. (Unpublished) http://www.iium.edu.my/icast |
| spellingShingle | QD Chemistry Darnis, Deny Susanti Awang, Anis Fadhlina Izyani Bakhtiar, M. Taher The mode of antimicrobial action of Cinnamomum burmannii’s essential oil & cinnamaldehyde |
| title | The mode of antimicrobial action of Cinnamomum burmannii’s essential oil & cinnamaldehyde |
| title_full | The mode of antimicrobial action of Cinnamomum burmannii’s essential oil & cinnamaldehyde |
| title_fullStr | The mode of antimicrobial action of Cinnamomum burmannii’s essential oil & cinnamaldehyde |
| title_full_unstemmed | The mode of antimicrobial action of Cinnamomum burmannii’s essential oil & cinnamaldehyde |
| title_short | The mode of antimicrobial action of Cinnamomum burmannii’s essential oil & cinnamaldehyde |
| title_sort | mode of antimicrobial action of cinnamomum burmannii’s essential oil & cinnamaldehyde |
| topic | QD Chemistry |
| url | http://irep.iium.edu.my/44303/ http://irep.iium.edu.my/44303/ http://irep.iium.edu.my/44303/1/44303.pdf |