Antimicrobial effect of Baccaurea angulata fruit extracts against human pathogenic microorganisms

The research application for drugs and food supplements derived from plants extracts have increased in recent years. Plants extract and their constituents are recognized to be safe, either because of their traditional use without any documented detrimental impact or because of dedicated toxicologic...

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Main Authors: Momand, Lailuma, Zakaria, Robaiza, Mikail, Maryam Abimbola, Kamal, Tara, Ibrahim, Muhammad, Abdul Wahab, Ridhwan
Format: Article
Language:English
Published: Merit Research Journals 2014
Subjects:
Online Access:http://irep.iium.edu.my/43509/
http://irep.iium.edu.my/43509/1/Laila_Publication__1_2014.pdf
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author Momand, Lailuma
Zakaria, Robaiza
Mikail, Maryam Abimbola
Kamal, Tara
Ibrahim, Muhammad
Abdul Wahab, Ridhwan
author_facet Momand, Lailuma
Zakaria, Robaiza
Mikail, Maryam Abimbola
Kamal, Tara
Ibrahim, Muhammad
Abdul Wahab, Ridhwan
author_sort Momand, Lailuma
building IIUM Repository
collection Online Access
description The research application for drugs and food supplements derived from plants extracts have increased in recent years. Plants extract and their constituents are recognized to be safe, either because of their traditional use without any documented detrimental impact or because of dedicated toxicological studies. The potential of higher plants as a source for new drugs is largely unexplored. Thus, a systematic investigation was undertaken to screen for antibacterial activity from Baccaurea angulata. Plant that belongs to the family is used as food as well as treatment of infectious diseases such as diarrhoea, skin infections and gonorrhoea. The anti-microbial activity of the B. angulata fruit extracts have revealed different antimicrobial properties, that vary between three parts (whole fruit, fruit skin, and berry), three solvents (methanol, ethanol and aqueous), using agar well diffusion, and microdilution methods and different pathogens (Streptococcus pneumoniae, Staphylococcus epidermidis, Klebsiella pneumoniae and Pseudomonas aeruginosa). The highest observed antimicrobial activity was in ethanol extract of fruit skin using agar well diffusion against S. pneumoniae. Among tested Gram negative bacteria, K. pneumoniae was the most susceptible bacterium which showed the highest bacteriostatic and bactericidal activity using microdilution method. All parts of fruit extracts poses the antimicrobial activities against all human pathogenic microorganisms used in this study.
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spelling iium-435092018-01-03T09:26:03Z http://irep.iium.edu.my/43509/ Antimicrobial effect of Baccaurea angulata fruit extracts against human pathogenic microorganisms Momand, Lailuma Zakaria, Robaiza Mikail, Maryam Abimbola Kamal, Tara Ibrahim, Muhammad Abdul Wahab, Ridhwan QK Botany QR Microbiology The research application for drugs and food supplements derived from plants extracts have increased in recent years. Plants extract and their constituents are recognized to be safe, either because of their traditional use without any documented detrimental impact or because of dedicated toxicological studies. The potential of higher plants as a source for new drugs is largely unexplored. Thus, a systematic investigation was undertaken to screen for antibacterial activity from Baccaurea angulata. Plant that belongs to the family is used as food as well as treatment of infectious diseases such as diarrhoea, skin infections and gonorrhoea. The anti-microbial activity of the B. angulata fruit extracts have revealed different antimicrobial properties, that vary between three parts (whole fruit, fruit skin, and berry), three solvents (methanol, ethanol and aqueous), using agar well diffusion, and microdilution methods and different pathogens (Streptococcus pneumoniae, Staphylococcus epidermidis, Klebsiella pneumoniae and Pseudomonas aeruginosa). The highest observed antimicrobial activity was in ethanol extract of fruit skin using agar well diffusion against S. pneumoniae. Among tested Gram negative bacteria, K. pneumoniae was the most susceptible bacterium which showed the highest bacteriostatic and bactericidal activity using microdilution method. All parts of fruit extracts poses the antimicrobial activities against all human pathogenic microorganisms used in this study. Merit Research Journals 2014-10 Article PeerReviewed application/pdf en http://irep.iium.edu.my/43509/1/Laila_Publication__1_2014.pdf Momand, Lailuma and Zakaria, Robaiza and Mikail, Maryam Abimbola and Kamal, Tara and Ibrahim, Muhammad and Abdul Wahab, Ridhwan (2014) Antimicrobial effect of Baccaurea angulata fruit extracts against human pathogenic microorganisms. Merit Research Journal of Medicine and Medical Sciences, 2 (10). pp. 229-237. ISSN 2354-323X http://meritresearchjournals.org/mms/content/2014/October/Momand%20et%20al.pdf
spellingShingle QK Botany
QR Microbiology
Momand, Lailuma
Zakaria, Robaiza
Mikail, Maryam Abimbola
Kamal, Tara
Ibrahim, Muhammad
Abdul Wahab, Ridhwan
Antimicrobial effect of Baccaurea angulata fruit extracts against human pathogenic microorganisms
title Antimicrobial effect of Baccaurea angulata fruit extracts against human pathogenic microorganisms
title_full Antimicrobial effect of Baccaurea angulata fruit extracts against human pathogenic microorganisms
title_fullStr Antimicrobial effect of Baccaurea angulata fruit extracts against human pathogenic microorganisms
title_full_unstemmed Antimicrobial effect of Baccaurea angulata fruit extracts against human pathogenic microorganisms
title_short Antimicrobial effect of Baccaurea angulata fruit extracts against human pathogenic microorganisms
title_sort antimicrobial effect of baccaurea angulata fruit extracts against human pathogenic microorganisms
topic QK Botany
QR Microbiology
url http://irep.iium.edu.my/43509/
http://irep.iium.edu.my/43509/
http://irep.iium.edu.my/43509/1/Laila_Publication__1_2014.pdf